中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (25): 4726-4730.doi: 10.3969/j.issn.1673-8225.2011.25.041

• 生物材料临床实践 clinical practice of biomaterials • 上一篇    下一篇

关节镜下自体肌腱及同种异体肌腱重建膝关节前后交叉韧带

马业涛,宋世锋,曾  凡,陈世强,肖海涛,刘福存,张熙民,许世忠,姚理阳   

  1. 海南省人民医院创伤骨科,海南省海口市  570311
  • 收稿日期:2011-03-23 修回日期:2011-05-17 出版日期:2011-06-18 发布日期:2014-01-10
  • 通讯作者: 宋世锋,主任医师,教授,海南省人民医院创伤骨科,海南省海口市 570311 songshif@126.com
  • 作者简介:马业涛,男,1967年生,海南省琼海市人,汉族,1991年海南医学院毕业,副主任医师,主要从事骨与关节创伤及矫形的研究。 mytzymz@163.com
  • 基金资助:

    海南省自然科学基金项目(2011-5-12)。

Arthroscopic anterior and posterior cruciate ligament reconstruction: Autograft versus allograft

Ma Ye-tao, Song Shi-feng, Zeng Fan, Chen Shi-qiang, Xiao Hai-tao, Liu Fu-cun, Zhang Xi-min, Xu Shi-zhong, Yao Li-yang   

  1. Department of Orthopaedics, Hainan Provincial People’s Hospital, Haikou  570311, Hainan Province, China
  • Received:2011-03-23 Revised:2011-05-17 Online:2011-06-18 Published:2014-01-10
  • Contact: Song Shi-feng, Chief physician, Professor, Department of Orthopaedics, Hainan Provincial People’s Hospital, Haikou 570311, Hainan Province, China songshif@126.com
  • About author:Ma Ye-tao, Associate chief physician, Department of Orthopaedics, Hainan Provincial People’s Hospital, Haikou 570311, Hainan Province, China mytzymz@163.com
  • Supported by:

    the Natural Science Foundation of Hainan Province, No. 2011-5-12*

摘要:

背景:自体肌腱移植重建膝关节前后交叉韧带已广泛应用,但是供区容易出现并发症,同种异体肌腱移植越来越多应用于重建膝关节前后交叉韧带,是一种重要的替代材料。
目的:比较关节镜下自体肌腱及同种异体肌腱移植重建膝关节前后交叉韧带的临床疗效差异。
方法:40 例前后交叉韧带损伤患者分为2组:自体肌腱组为自体半腱肌及股薄肌重建膝关节前后交叉韧带,异体肌腱组为应用由山西骨组织库提供的同种异体肌腱重建膝关节前后交叉韧带。
结果与结论:全部病例均获得6个月以上随访,最长随访时间36个月。重建前后两组大腿周径患健侧差值、Lachman 试验、中立位前抽屉试验(ADT)和国际膝关节评分委员会(IKDC)、Lysholm 及Tegner 评分差异均有显著性意义(P < 0.01),两组间术后各项指标差异均无显著性意义(P > 0.05)。结果表明,自体肌腱与单纯深低温冷冻同种异体肌腱移植在重建膝关节前后交叉韧带疗效无明显差异。

关键词: 前后交叉韧带, 关节镜, 自体肌腱, 同种异体肌腱, 移植

Abstract:

BACKGROUND: Using autologous tendon graft to reconstruct the knee cruciate ligament has been widely applied, but the technique has shortages such as donor site prone to complications, relatively longer operation time and greater trauma. So allogeneic tendon grafts have been applied as an important alternative materials in reconstructing knee cruciate ligament more and more frequently.
OBJECTIVE: To compare the clinical efficacy difference between using autologous tendon and allograft tendon to reconstruct knee cruciate ligament under arthroscopy.
METHODS: We had divided 40 cases of cruciate ligament injury into two groups: Group autologous tendon of 21 cases in which autogenous semitendinosus and gracilis muscle was used to reconstruct knee anterior and posterior cruciate ligament, while Group allograft tendon of 19 cases receiving allograft tendon provided by the Shanxi Province Bone Allograft Tendon Tissue Bank.
RESULTS AND CONCLUSION: All the patients were followed up for 6 to 36 months. There was statistical significance in contralateral thigh circumference difference, Lachman test, anterior drawer test in neutral position and the International Knee Documentation Committee scoring, Lysholm and Tegner scores between the two groups before and after surgery (P < 0.01). All the indexes showed no significant difference in the same group after surgery (P > 0.05). There was no significant difference in clinical efficacy between autologous tendon and allograft tendon with a simple deep-frozen tendon in anterior and posterior cruciate ligament reconstruction.

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