中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (26): 4770-4773.doi: 10.3969/j.issn.1673-8225.2010.26.005

• 数字化骨科 digital orthopedics • 上一篇    下一篇

个体化钛合金掌指关节假体的生物力学研究

王 鹏1，宣昭鹏2，赵承斌1，张 军1， 钱贵宾1，刘 灿3，路来金2   

  1. 1哈尔滨医科大学附属第四医院骨二科，黑龙江省哈尔滨市 154001；
    2吉林大学第一医院手外科，吉林省长春市 130021；
    3北京吉马飞科技发展有限公司，北京市100085
  • 出版日期:2010-06-25 发布日期:2010-06-25
  • 通讯作者: 路来金，教授，吉林大学第一医院手外科，吉林省长春市 130021 Lulaijin@ hotmail.com
  • 作者简介:王 鹏，男，1978年生，黑龙江省北安市人，汉族，吉林大学第一医院外科学毕业，博士，主治医师，主要从事个体化假体的设计与制造研究。 wangpengjms@ 163.com
  • 基金资助:

    吉林省科技厅科技发展计划项目资助课题(20060414-1)

Biomechanical changes in individualized metacarpophalangeal joint titanium alloy prosthesis

Wang Peng1, Xuan Zhao-peng 2, Zhao Cheng-bin1, Zhang Jun1, Qian Gui-bin1, Liu Can3, Lu Lai-jin 2   

  1. 1Second Department of Orthopaedics, Fourth Hospital of Harbin Medical University, Harbin   154001, Heilongjiang Province, China;
    2Department of Hand Surgery, First Hospital of Jilin University, Changchun  130021, Jilin Province, China; 3Beijing Jimafei Company, Beijing   100085, China
  • Online:2010-06-25 Published:2010-06-25
  • Contact: Lu Lai-jin, Professor, Department of Hand Surgery, First Hospital of Jilin University, Changchun 130021, Jilin Province, China Lulaijin@hotmail.com
  • About author:Wang Peng, Doctor, Attending physician, Second Department of Orthopaedics, Fourth Hospital of Harbin Medical University, Harbin 154001, Heilongjiang Province, China wangpengjms@163.com
  • Supported by:

    the Science and Technology Development Program of Jilin Science and Technology Department, No. 20060414-1*

PDF

419

被引次数

18

摘要：

背景：目前国内外对非个体化假体的生物力学研究较多，而对个体化假体的生物力学资料尚缺乏。
目的：探讨运用生物力学实验方法观测个体化假体生物力学的优越性。
方法： ①实验将经重建及快速成形制造的人个体化钛合金示指掌指关节标本设为个体化假体组；其对侧手标本的示指掌指关节为对照组；取5侧正常人手标本为正常对照组。在个体化假体组掌指关节植入个体化假体；对照组掌指关节植入Swanson假体。②利用CSS-44020试验机来模拟对3组标本分别以50，100，150，200，250，300，350 N施加垂直载荷。③观察相应掌、指骨所受的应变变化，并绘制相应的载荷－应变曲线，观察和对比个体化假体、Swanson假体和正常掌指关节的生物力学特点。
结果与结论：掌、指骨被垂直加压后，所受应变随着载荷加大而逐渐增大，观察各组数据，在实验测试范围内各应变片所测得应变值基本呈正态分布；掌骨在不同载荷下的应变要大于近节指骨。掌骨与近节指骨的应变变化在300~350 N出现了“平台期”。在压力为50 N时，各组掌、指骨所受的应变没有差别。大于100 N时，对照组与个体化假体、正常对照组应变相比差异均有显著性意义，而个体化假体、正常对照组间应变差异无显著性意义。说明个体化钛合金假体更符合掌指关节的解剖学形状，也就更符合正常掌指关节的生物力学，因此个体化钛合金假体要优于Swanson假体，为临床提供了一种新型理想的掌指关节假体。

关键词: 掌指关节, 个体化, 人工假体, 钛合金假体, 生物力学

Abstract:

BACKGROUND: Studies have been conducted regarding biomechanics of non-individualized prosthesis. But biomechanical data of individualized metacarpophalangeal (MP) joint prosthesis are few.
OBJECTIVE: To explore the superiority of biomechanical characters to detect biomechanics of individualized prosthesis.
METHODS: The experimental specimens were divided into three groups. Individualized prosthesis group (MP joints were replaced by individualized titanium alloy prosthesis), control group (MP joints were replaced by Swanson prosthesis) and normal group (normal human hand). Every group was subjected to vertical loading of 50, 100, 150, 200, 250, 300, and 350 N by CSS-44020 machine. The strain changes of metacarpal and phalanx bone were observed and the loading-strain curves were drawn. The biomechanics of individualized Titanium alloy prosthesis, Swanson prosthesis and normal MP joints were analyzed and compared.
RESULTS AND CONCLUSION: The strain of metacarpal and proximal phalanx bones was increased with increasing loadings. The strain of each test displayed normal distribution. The strain changes of metacarpal bones were greater than proximal phalanx bones at different loading. They all had “platform” period at 300-350 N. No significant strain changes were observed in each group under 50 N loading. The straining changes of control group were significantly different from the other groups when the loading was larger than 100 N. But no differences were observed between individualized prosthesis and normal groups. Results show that individualized titanium alloy prosthesis well matched anatomy of MP joint, and displayed better biomechanics compared with Swanson prosthesis. It provides a novel ideal MP joint for clinical application.

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