中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (9): 1669-1672.doi: 10.3969/j.issn.1673-8225.2010.09.035

• 干细胞综述 • 上一篇    下一篇

胆道金属支架再狭窄原因及支架置入的治疗展望

谭志刚1，郭奕彤2   

  1. 1沈阳医学院奉天医院急诊科，辽宁省沈阳市 110024；
    2沈阳市第九人民医院内六科，辽宁省沈阳市  110024
  • 出版日期:2010-02-26 发布日期:2010-02-26
  • 作者简介:谭志刚，男，1970年生，辽宁省沈阳市人，汉族，2006年吉林大学毕业，硕士，副主任医师，副教授，主要从事普外科肝胆疾病研究。 zhigangtan@sohu.com

Reasons for restenosis and treatment progress of biliary metal stent implantation

Tan Zhi-gang1, Guo Yi-tong2   

  1. 1Department of Emergency, Affiliated Fengtian Hospital of Shenyang Medical College, Shenyang  110024, Liaoning Province, China;
    2Sixth Department of Internal Medicine, Ninth People’s Hospital of Shenyang, Shenyang  110024,  Liaoning Province, China
  • Online:2010-02-26 Published:2010-02-26
  • About author:Tan Zhi-gang, Master, Associate chief physician, Associate professor, Department of Emergency, Affiliated Fengtian Hospital of Shenyang Medical College, Shenyang 110024, Liaoning Province, China zhigangtan@sohu.com

PDF

695

被引次数

23

摘要：

背景：胆管支架再狭窄是胆管支架置入后主要的远期并发症，成为影响其应用的关键问题。.
目的：旨在通过支架置入方法探讨导致胆道金属支架再狭窄的原因，同时评价支架置入方法治疗支架再狭窄的效果，寻找预防支架再狭窄的对策。
方法：由第一作者应用计算机检索PubMed、Cochrane图书馆、CNKI和维普数据库1989-01/2009-08相关文献。在标题和摘要中以“biliary metal stent ,reobstruction interventional therapy”或“胆管支架，再狭窄，介入治疗” 为检索词进行检索。选择文章内容与胆管支架再狭窄有关者，同一领域文献则选择近期发表或发表在权威杂志文章。初检得到171篇文献，根据纳入标准选择关于胆管支架再狭窄分析及处理的22篇文献进行综述。
结果与结论：肿瘤生长、胆砂形成及炎性增生为引起胆道金属支架再狭窄的主要原因。经皮经肝穿刺胆道引流术及胆道内支架置入为治疗支架再狭窄有效、安全的方法。同时注意术前患者一般状况的改善，及时发现和控制胆系感染，减少并发症，加强术后综合治疗，有望使支架开通时间延长，进一步提高治疗效果和改善患者的生活质量。

关键词: 胆管支架, 再狭窄, 支架置入治疗, 医学植入体, 综述文献

Abstract:

BACKGROUND: Biliary stent restenosis is one of the main long-term complications following biliary stent restenosis implantation, which affects its application. 
OBJECTIVE: To evaluate the reasons for the biliary stent restenosis and to explore corresponding prevention methods. 
METHODS: A computer-based online search of MEDLINE, Cochrane library, CNKI and VIP between January 1989 and August 2009 was performed to search related articles with the key words of “biliary metal stent, reobstruction, and interventional therapy”. Literatures related to biliary stent restenosis were selected, in the same field, the articles published lately or published by authoritative journals were preferred. A total of 171 articles were searched and 22 documents were included according to inclusion and exclusion criteria. 
RESULTS AND CONCLUSION: Tumor growth, gallstone formation and inflammatory hyperplasia are the main reasons for restenosis following biliary metal stent implantation. The interventional therapy is an effective way for the patients of stent restenosis. Simultaneously, the therapeutic efficacy and living quality of patients can be improved by noticing preoperative conditions, in-time detecting and controlling biliary infection, reducing complications as well as strengthening postoperative combined therapy.

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