[1] METSEMAKERS WJ, MORGENSTERN M, SENNEVILLE E, et al. General treatment principles for fracture-related infection: recommendations from an international expert group. Arch Orthop Trauma Surg. 2020;140(8):1013-1027.
[2] 化昊天,王新卫,张磊,等.慢性骨髓炎的诊疗研究进展[J].中国骨与关节杂志,2022,11(2): 132-136.
[3] 郝建强,韩涛,李闯兵,等.四肢长骨慢性骨髓炎清创研究进展[J].中国医学创新,2023, 20(13):179-182.
[4] LIU Y, YUSHAN M, LIU Z, et al. Complications of bone transport technique using the Ilizarov method in the lower extremity: a retrospective analysis of 282 consecutive cases over 10 years. BMC Musculoskelet Disord. 2020;21(1):354.
[5] 金磊,艾合买提江•玉素甫.长骨骨缺损手术治疗进展[J].中国骨与关节杂志,2021,10(9): 673-677.
[6] 邢浩,张永红,王栋.长骨大段骨缺损修复方法的优势与不足[J].中国组织工程研究,2021, 25(3):426-430.
[7] 李德满.负压封闭引流术治疗慢性化脓性骨髓炎患者的临床疗效观察[J].中国药物经济学,2018,13(8):106-108.
[8] WANG X, WEI F, LUO F, et al. Induction of granulation tissue for the secretion of growth factors and the promotion of bone defect repair. J Orthop Surg Res. 2015;10:147.
[9] 陈英华,黄巍峰,韦武,等.膜诱导技术在慢性创伤性骨髓炎中的应用进展[J].中外医疗, 2023,42(14):194-198.
[10] ALFORD AI, NICOLAOU D, HAKE M, et al. Masquelet’s induced membrane technique: Review of current concepts and future directions. J Orthop Res. 2021;39(4):707-718.
[11] LIODAKIS E, PACHA TO, AKTAS G, et al. [Biological reconstruction of large bone defects : Masquelet technique and new procedures]. Unfallchirurgie (Heidelb). 2023;126(3):184-189.
[12] HSU CA, CHEN SH, CHAN SY, et al. The Induced Membrane Technique for the Management of Segmental Tibial Defect or Nonunion: A Systematic Review and Meta-Analysis. Biomed Res Int. 2020;2020:5893642.
[13] 中华医学会骨科学分会,沈杰,陈林,等.膜诱导技术治疗感染性骨缺损临床循证指南(2023版)[J]. 中华创伤杂志,2023,39(2):107-120.
[14] GEURTS JAP, VAN VUGT TAG, ARTS JJC. Use of contemporary biomaterials in chronic osteomyelitis treatment: Clinical lessons learned and literature review. J Orthop Res. 2021; 39(2):258-264.
[15] WASSIF RK, ELKAYAL M, SHAMMA RN, et al. Recent advances in the local antibiotics delivery systems for management of osteomyelitis. Drug Deliv. 2021;28(1):2392-2414.
[16] SHI X, WU Y, NI H, et al. Antibiotic-loaded calcium sulfate in clinical treatment of chronic osteomyelitis: a systematic review and meta-analysis. J Orthop Surg Res. 2022;17(1): 104.
[17] MEREDDY P, NALLAMILLI SR, GOWDA VP, et al. The use of Stimulan in bone and joint infections. Bone Jt Open. 2023;4(7):516-522.
[18] SAMELIS PV, PAPAGRIGORAKIS E, SAMELI E, et al. Current Concepts on the Application, Pharmacokinetics and Complications of Antibiotic-Loaded Cement Spacers in the Treatment of Prosthetic Joint Infections. Cureus. 2022;14(1):e20968.
[19] VAN VUGT TAG, ARTS JJ, GEURTS JAP. Antibiotic-Loaded Polymethylmethacrylate Beads and Spacers in Treatment of Orthopedic Infections and the Role of Biofilm Formation. Front Microbiol. 2019;10:1626.
[20] XU T, WU KL, JIE K. Comprehensive meta-analysis of antibiotic-impregnated bone cement versus plain bone cement in primary total knee arthroplasty for preventing periprosthetic joint infection. Chin J Traumatol. 2022;25(6):325-330.
[21] LIU Y, LI X, LIANG A. Current research progress of local drug delivery systems based on biodegradable polymers in treating chronic osteomyelitis. Front Bioeng Biotechnol. 2022;10:1042128.
[22] COBB LH, MCCABE EM, PRIDDY LB. Therapeutics and delivery vehicles for local treatment of osteomyelitis. J Orthop Res. 2020;38(10): 2091-2103.
[23] GUILLÉN-CARVAJAL K, VALDEZ-SALAS B, BELTRÁN-PARTIDA E, et al. Chitosan, Gelatin, and Collagen Hydrogels for Bone Regeneration. Polymers (Basel). 2023;15(13):2762.
[24] SMITH M, ROBERTS M, AL-KASSAS R. Implantable drug delivery systems for the treatment of osteomyelitis. Drug Dev Ind Pharm. 2022;48(10):511-527.
[25] KRISHNAN AG, BISWAS R, MENON D, et al. Biodegradable nanocomposite fibrous scaffold mediated local delivery of vancomycin for the treatment of MRSA infected experimental osteomyelitis. Biomater Sci. 2020;8(9):2653-2665.
[26] YE B, WU B, SU Y, et al. Recent Advances in the Application of Natural and Synthetic Polymer-Based Scaffolds in Musculoskeletal Regeneration. Polymers (Basel). 2022;14(21):4566.
[27] FAN J, ABEDI-DORCHEH K, SADAT VAZIRI A, et al. A Review of Recent Advances in Natural Polymer-Based Scaffolds for Musculoskeletal Tissue Engineering. Polymers (Basel). 2022; 14(10):2097.
[28] DESAI N, RANA D, SALAVE S, et al. Chitosan: A Potential Biopolymer in Drug Delivery and Biomedical Applications. Pharmaceutics. 2023;15(4):1313.
[29] TAO F, MA S, TAO H, et al. Chitosan-based drug delivery systems: From synthesis strategy to osteomyelitis treatment - A review. Carbohydr Polym. 2021;251:117063.
[30] QIN Y, LI P. Antimicrobial Chitosan Conjugates: Current Synthetic Strategies and Potential Applications. Int J Mol Sci. 2020;21(2):499.
[31] CONFEDERAT LG, TUCHILUS CG, DRAGAN M, et al. Preparation and Antimicrobial Activity of Chitosan and Its Derivatives: A Concise Review. Molecules. 2021;26(12):3694.
[32] KONG M, CHEN X G, XING K, et al. Antimicrobial properties of chitosan and mode of action: a state of the art review. Int J Food Microbiol. 2010;144(1):51-63.
[33] TAO J, ZHANG Y, SHEN A, et al. Injectable Chitosan-Based Thermosensitive Hydrogel/Nanoparticle-Loaded System for Local Delivery of Vancomycin in the Treatment of Osteomyelitis. Int J Nanomedicine. 2020;15:5855-5871.
[34] YANG Y, CHU L, YANG S, et al. Dual-functional 3D-printed composite scaffold for inhibiting bacterial infection and promoting bone regeneration in infected bone defect models. Acta Biomater. 2018;79:265-275.
[35] ZHENG M, WANG X, CHEN Y, et al. A Review of Recent Progress on Collagen-Based Biomaterials. Adv Healthc Mater. 2023;12(16):e2202042.
[36] GRABSKA-ZIELIŃSKA S, SIONKOWSKA A, CARVALHO Â, et al. Biomaterials with Potential Use in Bone Tissue Regeneration-Collagen/Ch:itosan/Silk Fibroin Scaffolds Cross-Linked by EDC/NHS. Materials (Basel). 2021;14(5):1105.
[37] ALEGRETE N, SOUSA SR, PADRÃO T, et al. Vancomycin-Loaded, Nanohydroxyapatite-Based Scaffold for Osteomyelitis Treatment: In Vivo Rabbit Toxicological Tests and In Vivo Efficacy Tests in a Sheep Model. Bioengineering (Basel). 2023;10(2):206.
[38] WU H, LIN K, ZHAO C, et al. Silk fibroin scaffolds: A promising candidate for bone regeneration. Front Bioeng Biotechnol. 2022;10:1054379.
[39] ZHANG L, ZHANG W, HU Y, et al. Systematic Review of Silk Scaffolds in Musculoskeletal Tissue Engineering Applications in the Recent Decade. ACS Biomater Sci Eng. 2021;7(3):817-840.
[40] SHABBIRAHMED AM, SEKAR R, GOMEZ LA, et al. Recent Developments of Silk-Based Scaffolds for Tissue Engineering and Regenerative Medicine Applications: A Special Focus on the Advancement of 3D Printing. Biomimetics (Basel). 2023;8(1):16.
[41] LI M, YOU J, QIN Q, et al. A Comprehensive Review on Silk Fibroin as a Persuasive Biomaterial for Bone Tissue Engineering. Int J Mol Sci. 2023;24(3):2660.
[42] ZHAI X, WU Y, TAN H. Gelatin-based Targeted Delivery Systems for Tissue Engineering. Curr Drug Targets. 2023;24(8):673-687.
[43] BELLO AB, KIM D, KIM D, et al. Engineering and Functionalization of Gelatin Biomaterials: From Cell Culture to Medical Applications. Tissue Eng Part B Rev. 2020;26(2):164-180.
[44] BAYER IS. Hyaluronic Acid and Controlled Release: A Review. Molecules. 2020;25(11):2649.
[45] HWANG HS, LEE CS. Recent Progress in Hyaluronic-Acid-Based Hydrogels for Bone Tissue Engineering. Gels. 2023;9(7):588.
[46] ZHANG H, CHENG J, AO Q. Preparation of Alginate-Based Biomaterials and Their Applications in Biomedicine. Mar Drugs. 2021;19(5):264.
[47] FARSHIDFAR N, IRAVANI S, VARMA RS. Alginate-Based Biomaterials in Tissue Engineering and Regenerative Medicine. Mar Drugs. 2023;21(3):189.
[48] SHARMA S, SUDHAKARA P, SINGH J, et al. Critical Review of Biodegradable and Bioactive Polymer Composites for Bone Tissue Engineering and Drug Delivery Applications. Polymers (Basel). 2021;13(16):2623.
[49] BHARADWAZ A, JAYASURIYA AC. Recent trends in the application of widely used natural and synthetic polymer nanocomposites in bone tissue regeneration. Mater Sci Eng C Mater Biol Appl. 2020;110:110698.
[50] LV XF, ZHOU DM, SUN XH, et al. Nano Sized Hydroxyapatite-Polylactic Acid-Vancomycin in Alleviation of Chronic Osteomyelitis. Drug Des Devel Ther. 2022;16:1983-1993.
[51] LI G, ZHAO M, XU F, et al. Synthesis and Biological Application of Polylactic Acid. Molecules. 2020;25(21):5023.
[52] SU Y, ZHANG B, SUN R, et al. PLGA-based biodegradable microspheres in drug delivery: recent advances in research and application. Drug Deliv. 2021;28(1):1397-1418.
[53] ZHOU S, LIU S, WANG Y, et al. Advances in the Study of Bionic Mineralized Collagen, PLGA, Magnesium Ionomer Materials, and Their Composite Scaffolds for Bone Defect Treatment. J Funct Biomater. 2023;14(8):406.
[54] JIN S, XIA X, HUANG J, et al. Recent advances in PLGA-based biomaterials for bone tissue regeneration. Acta Biomater. 2021;127:56-79.
[55] ESSA D, KONDIAH PPD, CHOONARA YE, et al. The Design of Poly(lactide-co-glycolide) Nanocarriers for Medical Applications. Front Bioeng Biotechnol. 2020;8:48.
[56] LU Y, CHENG D, NIU B, et al. Properties of Poly (Lactic-co-Glycolic Acid) and Progress of Poly (Lactic-co-Glycolic Acid)-Based Biodegradable Materials in Biomedical Research. Pharmaceuticals (Basel). 2023;16(3):454.
[57] CHAVAN YR, TAMBE SM, JAIN DD, et al. Redefining the importance of polylactide-co-glycolide acid (PLGA) in drug delivery. Ann Pharm Fr. 2022;80(5): 603-616.
[58] LI J, LI K, DU Y, et al. Dual-Nozzle 3D Printed Nano-Hydroxyapatite Scaffold Loaded with Vancomycin Sustained-Release Microspheres for Enhancing Bone Regeneration. Int J Nanomedicine. 2023;18:307-322.
[59] MISTRY S, ROY R, JHA AK, et al. Treatment of long bone infection by a biodegradable bone cement releasing antibiotics in human. J Control Release. 2022;346:180-192.
[60] SUN F, SUN X, WANG H, et al. Application of 3D-Printed, PLGA-Based Scaffolds in Bone Tissue Engineering. Int J Mol Sci. 2022;23(10):5831.
[61] LI S, SHI X, XU B, et al. In vitro drug release and antibacterial activity evaluation of silk fibroin coated vancomycin hydrochloride loaded poly (lactic-co-glycolic acid) (PLGA) sustained release microspheres. J Biomater Appl. 2022;36(9):1676-1688.
[62] DWIVEDI R, KUMAR S, PANDEY R, et al. Polycaprolactone as biomaterial for bone scaffolds: Review of literature. J Oral Biol Craniofac Res. 2020;10(1):381-388.
[63] GHARIBSHAHIAN M, SALEHI M, BEHESHTIZADEH N, et al. Recent advances on 3D-printed PCL-based composite scaffolds for bone tissue engineering. Front Bioeng Biotechnol. 2023;11:1168504.
[64] YANG X, WANG Y, ZHOU Y, et al. The Application of Polycaprolactone in Three-Dimensional Printing Scaffolds for Bone Tissue Engineering. Polymers (Basel). 2021;13(16):2754.
[65] WANG Q, YE W, MA Z, et al. 3D printed PCL/β-TCP cross-scale scaffold with high-precision fiber for providing cell growth and forming bones in the pores. Mater Sci Eng C Mater Biol Appl. 2021;127:112197.
[66] LÓPEZ-GONZÁLEZ I, HERNÁNDEZ-HEREDIA AB, RODRÍGUEZ-LÓPEZ MI, et al. Evaluation of the In Vitro Antimicrobial Efficacy against Staphylococcus aureus and epidermidis of a Novel 3D-Printed Degradable Drug Delivery System Based on Polycaprolactone/Chitosan/Vancomycin-Preclinical Study. Pharmaceutics. 2023;15(6):1763.
[67] CAI Z, WAN Y, BECKER ML, et al. Poly(propylene fumarate)-based materials: Synthesis, functionalization, properties, device fabrication and biomedical applications. Biomaterials. 2019;208:45-71.
[68] 杨峰,马春蒙,王靖,等.可注射PPF骨水泥的制备与固化性能[J].功能高分子学报, 2018,31(1):51-56.
[69] GAO J, LIU X, CHENG J, et al. Application of photocrosslinkable hydrogels based on photolithography 3D bioprinting technology in bone tissue engineering. Regen Biomater. 2023; 10: rbad037.doi: 10.1093/rb/rbad037.
[70] LUO Y, LE FER G, DEAN D, et al. 3D Printing of Poly(propylene fumarate) Oligomers: Evaluation of Resin Viscosity, Printing Characteristics and Mechanical Properties. Biomacromolecules. 2019;20(4):1699-1708.
[71] GUERRA AJ, LARA-PADILLA H, BECKER ML, et al. Photopolymerizable Resins for 3D-Printing Solid-Cured Tissue Engineered Implants. Curr Drug Targets. 2019;20(8):823-838.
[72] CHENG T, QU H, ZHANG G, et al. Osteogenic and antibacterial properties of vancomycin-laden mesoporous bioglass/PLGA composite scaffolds for bone regeneration in infected bone defects. Artif Cells Nanomed Biotechnol. 2018;46(8):1935-1947.
[73] KAUR G, KUMAR V, BAINO F, et al. Mechanical properties of bioactive glasses, ceramics, glass-ceramics and composites: State-of-the-art review and future challenges. Mater Sci Eng C Mater Biol Appl. 2019;104:109895.
[74] ZENG M, XU Z, SONG ZQ, et al. Diagnosis and treatment of chronic osteomyelitis based on nanomaterials. World J Orthop. 2023;14(2):42-54.
[75] 马士卿,王洁,高平,等.生物降解微球在骨组织再生中的生物学优势[J].中国组织工程研究,2021,25(34):5517-5522.
[76] ZHU H, ZHENG K, BOCCACCINI AR. Multi-functional silica-based mesoporous materials for simultaneous delivery of biologically active ions and therapeutic biomolecules. Acta Biomater. 2021;129:1-17.
[77] BURDUȘEL AC, GHERASIM O, ANDRONESCU E, et al. Inorganic Nanoparticles in Bone Healing Applications. Pharmaceutics. 2022;14(4):770.
[78] KIM SK, MURUGAN SS, DALAVI PA, et al. Biomimetic chitosan with biocomposite nanomaterials for bone tissue repair and regeneration. Beilstein J Nanotechnol. 2022;13:1051-1067.
[79] V K AD, RAY S, ARORA U, et al. Dual drug delivery platforms for bone tissue engineering. Front Bioeng Biotechnol. 2022;10:969843.
[80] RITSCHL L, SCHILLING P, WITTMER A, et al. Composite material consisting of microporous beta-TCP ceramic and alginate-dialdehyde-gelatin for controlled dual release of clindamycin and bone morphogenetic protein 2. J Mater Sci Mater Med. 2023;34(8):39.
[81] YAZDANPANAH Z, JOHNSTON JD, COOPER DML, et al. 3D Bioprinted Scaffolds for Bone Tissue Engineering: State-Of-The-Art and Emerging Technologies. Front Bioeng Biotechnol. 2022;10: 824156.
[82] ABDELAZIZ AG, NAGEH H, ABDO SM, et al. A Review of 3D Polymeric Scaffolds for Bone Tissue Engineering: Principles, Fabrication Techniques, Immunomodulatory Roles, and Challenges. Bioengineering (Basel). 2023;10(2):204.
[83] TEWARI AK, UPADHYAY SC, KUMAR M, et al. Insights on Development Aspects of Polymeric Nanocarriers: The Translation from Bench to Clinic. Polymers (Basel). 2022;14(17):3545.
[84] BIRK SE, BOISEN A, NIELSEN LH. Polymeric nano- and microparticulate drug delivery systems for treatment of biofilms. Adv Drug Deliv Rev. 2021;174:30-52.
[85] YANG J, YAO JL, WU ZQ, et al. Current opinions on the mechanism, classification, imaging diagnosis and treatment of post-traumatic osteomyelitis. Chin J Traumatol. 2021;24(6): 320-327.
[86] WANG X, ZHANG M, ZHU T, et al. Flourishing Antibacterial Strategies for Osteomyelitis Therapy. Adv Sci (Weinh). 2023;10(11): e2206154.
[87] WENHAO Z, ZHANG T, YAN J, et al. In vitro and in vivo evaluation of structurally-controlled silk fibroin coatings for orthopedic infection and in-situ osteogenesis. Acta Biomater. 2020;116:223-245. |