中国组织工程研究 ›› 2019, Vol. 23 ›› Issue (35): 5582-5586.doi: 10.3969/j.issn.2095-4344.1902

• 骨组织构建 bone tissue construction • 上一篇    下一篇

不同年龄段中、晚期孕妇骨密度水平的差异性比较

黄丽仟,孔存青,舒文博,周  鹤,赖秋荣,陈  润,唐  成,杨雅茱,张文海,刘  鹏   

  1. (广西医科大学基础医学院解剖教研室,广西壮族自治区南宁市  530021)
  • 收稿日期:2019-06-14 出版日期:2019-12-18 发布日期:2019-12-18
  • 通讯作者: 刘鹏,硕士,副教授,广西医科大学基础医学院解剖教研室,广西壮族自治区南宁市 530021
  • 作者简介:黄丽仟,女,1994年生,广西壮族自治区德保县人,壮族,广西医科大学在读硕士,主要从事体质人类学研究。
  • 基金资助:

    广西高校科学技术研究重点项目(KY2015ZD024),项目负责人:刘鹏;广西医科大学大学生创新创业训练计划项目(2018009,2018112),项目负责人:刘鹏

Comparison of bone mineral density levels in women of different ages during middle and late pregnancies

Huang Liqian, Kong Cunqing, Shu Wenbo, Zhou He, Lai Qiurong, Chen Run, Tang Cheng, Yang Yazhu,
Zhang Wenhai, Liu Peng   

  1.  (Department of Anatomy, School of Preclinical Medicine, Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China)
  • Received:2019-06-14 Online:2019-12-18 Published:2019-12-18
  • Contact: Liu Peng, Master, Associate professor, Department of Anatomy, School of Preclinical Medicine, Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China
  • About author:Huang Liqian, Master candidate, Department of Anatomy, School of Preclinical Medicine, Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China
  • Supported by:

    the Key Project of Science and Technology Research of Guangxi Universities, No. KY2015ZD024 (to LP); the Innovation and Entrepreneurship Training Program for College Students of Guangxi Medical University, No. 2018009 and 2018112 (to LP)

摘要:

文章快速阅读:

文题释义:

超声定量骨密度仪:是通过被测物体对超声波的吸收、振幅衰减以及超声波的反射来反映骨矿含量多少和骨结构及骨强度的情况,可较全面地客观评价骨的营养状况。超声骨密度仪无创伤性,无电离辐射,操作方便简单,且可重复进行,孕妇易于接受。
骨质疏松:即骨质疏松症,是多种原因引起的一组骨病,骨组织有正常的钙化,钙盐与基质呈正常比例,以单位体积内骨组织量减少为特点的代谢性骨病变。
摘要
背景:
随着优生优育意识的增强和国家二胎政策的开放,人们对于孕期保健也日益重视,尤其是妊娠期营养的摄入和骨质健康状况越来越受社会的关注。
目的:通过比较和分析不同年龄、不同孕期妇女骨密度的变化情况,为孕产妇保健工作提供科学合理营养指导,预防孕期骨密度下降。
方法:选择2017年6月至2018年4月在南宁市第八人民医院产检的不同孕期孕妇531例,均为广西籍贯原住居民,均自愿参加检测,并签署知情同意书。将其按照孕周和年龄进行分组,并对各组孕妇的桡骨骨密度进行超声检测,并对孕期年龄、孕周与骨密度进行相关性分析。
结果与结论:①中、晚孕期女性骨密度降低情况差异无显著性意义(P > 0.05);②不同年龄孕期女性的声速值和T值差异有显著性意义,且随年龄增加呈上升趋势(P < 0.05);③孕中期女性的声速值和T值均随年龄增加呈上升趋势,差异有显著性意义(P < 0.05),而孕晚期女性的骨密度指标在不同年龄组之间差异无显著性意义(P > 0.05);④提示孕中期和孕晚期女性的骨密度差异不显著,但年龄是影响孕妇骨密度的因素之一;关注孕期骨密度变化,对增强母体的骨质健康和保证胎儿正常发育有重要意义。 ORCID: 0000-0002-0160-9526(黄丽仟)

关键词: 孕妇, 年龄, 骨密度, 桡骨, 超声, 孕中期, 孕晚期

Abstract:

BACKGROUND: With the increasing awareness of eugenics and the opening up of the National Policy of Second Child, people pay more and more attention to health care during pregnancy, especially nutrition intake and bone health status during pregnancy.
OBJECTIVE: To provide scientific and rational nutrition guidance for maternal health care and prevent bone mineral density from decreasing during pregnancy by comparing and analyzing the changes of bone mineral density in women of different ages and gestational periods.
METHODS: Totally 531 pregnant women admitted to the hospital from June 2017 to April 2018 were selected. All participants were native residents of Guangxi Zhuang Autonomous Region, volunteered to the trial, and signed the informed consents. They were signed by pregnancy week and age. The bone mineral density of radius of pregnant women in each group was measured by ultrasound. Correlation analysis of age, pregnancy week and bone mineral density was conducted.
RESULTS AND CONCLUSION: (1) There was no significant difference in the bone mineral density decrease between middle and late pregnant women (P > 0.05). (2) The speed of sound and T values of pregnant women of different ages had significant difference, and increased with age (P < 0.05). (3) The speed of sound and T values in the second trimester increased with age, and there was a significant difference (P < 0.05). There was no significant difference in the bone mineral density between the different age groups in the third trimester (P > 0.05). (4) These results indicate that bone mineral density changes should be regularly detected in the middle and late pregnancies, and the calcium deficiency and bone condition of pregnant women should be known in time. Nutritional intervention should be carried out in the early stage to ensure maternal bone health and normal fetal development.

Key words: pregnant women, age, bone mineral density, radius, ultrasound, middle pregnancy, late pregnancy

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