中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (16): 2935-2938.doi: 10.3969/j.issn.1673-8225.2012.16.020

• 材料力学及表面改性 material mechanics and surface modification • 上一篇    下一篇

聚甲基丙烯酸甲酯骨水泥与Cortoss骨水泥生物力学性能及聚合温度比较★

钱  明,潘  俊,孟  斌,张  文,朱法豪,曹  成,罗宗平,杨惠林   

  1. 苏州大学附属第一医院骨科,江苏省苏州市   215006
  • 收稿日期:2011-10-05 修回日期:2012-01-12 出版日期:2012-04-15 发布日期:2012-04-15
  • 通讯作者: 杨惠林,博士,博士生导师、主任医师,苏州大学附属第一医院骨科,江苏省苏州市 215006 suzhouspine@ 163.com
  • 作者简介:钱明★,男,1985年生,江苏省南通市人,汉族,苏州大学附属第一医院在读硕士,主要从事脊柱外科方面的研究。 qianming85@ 163.com

Comparison of biomechanics property and exotherm between polymethylmethacrylate bone cement and Cortoss bone cement  

Qian Ming, Pan Jun, Meng Bin, Zhang Wen, Zhu Fa-hao, Cao Cheng, Luo Zong-ping, Yang Hui-lin   

  1. Department of Orthopedics, First Affiliated Hospital of Soochow University, Suzhou  215006, Jiangsu Province, China
  • Received:2011-10-05 Revised:2012-01-12 Online:2012-04-15 Published:2012-04-15
  • Contact: author: Yang Hui-lin, Doctor, Chief physician, Department of Orthopedics, First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China suzhouspine@ 163.com
  • About author:Qian Ming★, Studying for master’s degree, Department of Orthopedics, First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China qianming85@ 163.com

摘要:

背景:聚甲基丙烯酸甲酯骨水泥是其最常用的一种填充材料,但由于其存在聚合时放热、单体毒性等缺点,所以目前出现了以Cortoss为代表的生物新型骨水泥。
目的:对比两种骨水泥在体外的力学性能。
方法:将聚甲基丙烯酸甲酯与新型骨水泥Cortoss按照ISO5833:2002标准分别制作成抗压及抗弯模型,将制作的模型使用生物力学机测试两种骨水泥的抗弯及抗压模量,同时在制模过程中测量骨水泥聚合温度。
结果与结论:与聚甲基丙烯酸甲酯骨水泥比较,Cortoss骨水泥在聚合过程中最高温度较低、抗压强度较强、抗弯模量降低,差异均有显著性意义(P < 0.05),而抗弯强度间差异无显著性意义(P > 0.05)。说明Cortoss生物力学强度优于聚甲基丙烯酸甲酯骨水泥,由于Cortoss在聚合时放热较少,所以其用于手术时有较好的安全性。
 

关键词: 聚甲基丙烯酸甲酯, 骨水泥, 生物力学, Cortoss, 经皮椎体后凸成形

Abstract:

BACKGROUND: Polymethylmethacrylate (PMMA) is a kind of bone cement commonly used for percutaneous kyphoplasty (PKP). However, it has inherent drawbacks, including a high curing exotherm and the incorporation of toxic components in their formulations. Now, there are some new biological bone cements, for example, Cortoss.
OBJECTIVE: To compare the in vitro biomechanical properties of PMMA bone cement and Cortoss bone cement.
METHODS: Both PMMA bone cement and Cortoss bone cement were used to make the anti-compression and anti-bending models according to ISO 5833:2002. Then, the compressive load strength and bending load strength were tested using mechanical testing machine. During the modeling process, the polymerization temperature was tested in their formulations.
RESULTS AND CONCLUSION: The peak exotherm and bending modulus of Cortoss were significantly lower than those of PMMA, and the compressive strength was stronger than that of PMMA (P < 0.05). However, there was no significant difference in bending strength (P < 0.05 ). The biomechanical strength of Cortoss bone cement was better than that of PMMA bone cement. Due to its lower exotherm, Cortoss bone cement was safer during the operation.

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