中国组织工程研究 ›› 2023, Vol. 27 ›› Issue (9): 1396-1402.doi: 10.12307/2023.205

• 骨与关节图像与影像 bone and joint imaging • 上一篇    下一篇

压缩感知技术在踝关节2D MR成像中的应用

杜雪婷1,张晓东2,陈焱君2,王  梅3,陈武标1,黄文华4,5   

  1. 广东医科大学附属医院,1放射科,4骨科,广东省湛江市   524001;2南方医科大学第三附属医院放射科,广东省广州市   510000;3广州市第一人民医院南沙医院放射科,广东省广州市   511458;5南方医科大学基础医学院人体解剖学国家重点学科,广东省医学生物力学重点实验室,广东省医学3D打印应用转化工程技术研究中心,广东省广州市   510515
  • 收稿日期:2021-12-23 接受日期:2022-01-22 出版日期:2023-03-28 发布日期:2022-07-01
  • 通讯作者: 黄文华,博士,博士生导师,教授,广东医科大学附属医院骨科,广东省湛江市 524001;南方医科大学基础医学院人体解剖学国家重点学科,广东省医学生物力学重点实验室,广东省医学3D打印应用转化工程技术研究中心,广东省广州市 510515 陈武标,主任医师,硕士生导师,广东医科大学附属医院放射科,广东省湛江市 524001
  • 作者简介:杜雪婷,女,1997 年生,河南省驻马店市人,汉族,硕士,放射技师,主要从事磁共振方面的研究。
  • 基金资助:
    广东省科技计划项目(2016B090917001),项目负责人:黄文华;广东省科技计划项目(2017B090912006),项目负责人:张晓东;深圳市医疗卫生“三名工程”高层次医学团队(SZSM201612019),项目负责人:黄文华;广东省基础与应用基础研究基金(2020B1515120001),项目参与人:黄文华

Application of compressed sensing technology in two-dimensional magnetic resonance imaging of the ankle joint

Du Xueting1, Zhang Xiaodong2, Chen Yanjun2, Wang Mei3, Chen Wubiao1, Huang Wenhua4, 5   

  1. 1Department of Radiology, 4Department of Orthopedics, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001; 2Department of Radiology, Third Affiliated Hospital of Southern Medical University, Guangzhou 510000; 3Department of Radiology, Nansha Hosptial, Guangzhou First People’s Hosptial, Guangzhou 511458; 5Guangdong Engineering Research Center for Translation of Medical 3D Printing Application, Guangzhou 510515
  • Received:2021-12-23 Accepted:2022-01-22 Online:2023-03-28 Published:2022-07-01
  • Contact: Huang Wenhua, MD, Doctoral supervisor, Professor, Department of Orthopedics, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, Guangdong Province, China; Guangdong Engineering Research Center for Translation of Medical 3D Printing Application, Guangdong Provincial Key Laboratory of Medical Biomechanics, National Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, Guangdong Province, China Chen Wubiao, Chief physician, Master’s supervisor, Department of Radiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, Guangdong Province, China
  • About author:Du Xueting, Master, Technician, Department of Radiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, Guangdong Province, China
  • Supported by:
    Science and Technology Planning Project of Guangdong Province, No. 2016B090917001 (to HWH), No. 2017B090912006 (to ZXD); “Sanming Project” of Medicine in Shenzhen, No. SZSM201612019 (to HWH); Fundamental and Applied Basic Research Fund of Guangdong Province, No. 2020B1515120001 (to HWH)

摘要:

文题释义:
并行成像技术:采用等间隔性采样,利用相控线圈多通道接受信号的独立性和空间位置上灵敏度的差异性,减少相位编码采集从而减少了采样数据量,而提高成像速度。该文敏感度编码SENSE技术是利用SENSE算法的并行成像采集技术,对采集数据通过傅里叶转换后再去卷褶伪影的成像技术。
压缩感知技术:在2006年由DONOHO等学者提出压缩感知理论,2007年首次在MRI中应用,与并行成像技术的等间隔性采集方式不同,压缩感知技术成像时对K空间采用随机欠采样,使用低于奈奎斯特采样定律的频率获取K空间数据,后用非线性迭代重建算法修复欠采样的K空间数据得到图像,提高了传统全采样方法的成像速度。

背景:目前压缩感知技术用于踝关节MRI应用的报道较少。
目的:探讨不同加速因子的压缩感知技术对踝关节常规2D-MRI图像质量和扫描时间的影响。
方法:对24名健康志愿者(38个踝关节)在3.0T MR行常规2D-TSE序列扫描,基于敏感编码SENSE并行成像(S组)和压缩感知技术(CS组),分别获取轴位T1WI(加速因子分别为S1.3、CS1.3、CS1.9、CS2.7)、矢状位PDWI加速因子分别为S1.8、CS1.8、CS2.6、CS3.2)、冠状位PDWI(加速因子分别为S1.3、CS1.3、CS1.6、CS2.0)序列图像,每个序列的其他扫描参数保持一致。对踝关节图像的肌腱、软骨、韧带和肌肉结构进行5分主观评分,测量骨、软骨、韧带、肌腱、肌肉、积液、脂肪结构的背景噪声标准差和信号强度,计算其信噪比和对比噪声比,对不同加速因子成像的主观评分和客观评价进行统计学分析,每个序列图像质量以SENSE组(S组)为标准参考。
结果与结论:①当加速因子相同时,常规序列S组和CS组的主观评分、信噪比和对比噪声比差异均无显著性意义(P > 0.05);②当CS(轴位T1WIA)、CS(矢状位PDWI)、CS(冠状位PDWI)序列的加速因子分别在1.9、2.6、1.6时,软骨、肌腱、韧带等踝关节主要观察结构的图像质量均无明显差异(P > 0.05),扫描时间分别是1 min 32 s、1 min 42 s、1 min 48 s;当CS(轴位T1WI)、CS(矢状位PDWI)、CS(冠状位PDWI)序列的加速因子分别增加至2.7、3.2、2.0时,所有解剖结构的主观评分分数仍大于3分,但每个序列均出现信噪比和对比噪声比显著下降(P < 0.05);③结果提示,当加速因子相同时,CS组获取的图像质量总体高于S组;当加速因子增大时,CS序列的扫描时间逐渐减少,图像质量也随之降低;在3.0T MR仪上,压缩感知技术应用在常规2D序列轴位T1WI、矢状位PDWI和冠状位PDWI时,分别推荐1.9、2.6、1.6加速因子,整体时间可减少约27%(1 min 53 s)。

https://orcid.org/0000-0002-1947-7488 (杜雪婷)

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱;骨折;内固定;数字化骨科;组织工程

关键词: 磁共振成像, 踝关节, 压缩感知, 加速因子, 图像质量

Abstract: BACKGROUND: At present, there are few reports on the application of compressed sensing technology in ankle MRI. 
OBJECTIVE: To investigate the effect of different acceleration factors in compressed sensing (CS) on image quality and scanning time of conventional 2D-MRI of the ankle joint. 
METHODS: Totally 24 healthy volunteers (38 ankles) underwent conventional 2D-TSE sequence scanning at 3.0T MR. Based on SENSE parallel imaging (S group) and compressed sensing technique (CS group), sequence images of T1WI-TRA (S1.3, CS1.3, CS1.9, CS2.7), PDWI-Dixon-SAG (S1.8, CS1.8, CS2.6, CS3.2) and PDWI-SPAIR-COR (S1.3, CS1.3, CS1.6, CS2.0) were obtained separately. Other scan parameters of each sequence remained consistent. The tendon, cartilage, ligament and muscle structures of the ankle joint images were subjectively scored by 5 points. The standard deviation of background noise and signal intensity of bone, cartilage, ligament, tendon, muscle, effusion and fat structures were measured, and the signal-to-noise ratio and contrast-to-noise ratio were calculated. The subjective score and objective evaluation of different acceleration factor images were statistically analyzed. SENSE group was used as the standard reference for the image quality of each sequence. 
RESULTS AND CONCLUSION: (1) When acceleration factor was the same, there were no statistically significant differences in subjective score, signal-to-noise ratio and contrast-to-noise ratio between the S group and the CS group (P > 0.05). (2) The acceleration factor of CS (TRA), CS (SAG) and CS (COR) sequences at CS1.9, CS2.6 and CS1.6 showed no significant difference in the image quality of cartilage, tendon, ligament and other main observed structures of the ankle joint (P > 0.05), and the scanning time was 1 minute and 32 seconds, 1 minute and 42 seconds, 1 minute and 48 seconds, respectively. When the acceleration factor of CS (TRA), CS (SAG) and CS (COR) sequences increased to CS2.7, CS3.2 and CS2.0, respectively, the subjective scores of all anatomical structures were still greater than 3, but signal-to-noise ratio and contrast-to-noise ratio of each sequence decreased significantly (P < 0.05). (3) These findings confirm that when acceleration factor is the same, compared with CS group, the image quality obtained by CS group is generally higher than that of S group. When acceleration factor increases, the scanning time of CS sequence decreases gradually, and the image quality also decreases. On a 3.0T MR, CS technology recommended CS1.9, CS2.6, and CS1.6 accelerators for conventional 2D sequences T1WI-TRA, PDWI-Dixon-SAG, and PDWI-SPAIR-COR, respectively, reducing the overall time by about 27% (1 minute and 53 seconds).

Key words: magnetic resonance imaging, ankle joint, compressed sensing, acceleration factor, image quality

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