中国组织工程研究

中国组织工程研究 ›› 2016, Vol. 20 ›› Issue (8): 1126-1132.doi: 10.3969/j.issn.2095-4344.2016.08.009

• 组织工程骨及软骨材料 tissue-engineered bone and cartilage materials • 上一篇    下一篇

可吸收内固定材料修复髌骨横断性骨折

王 峰1，贾金领2   

  1. 1南阳市中心医院骨二科，河南省南阳市 473000；2新乡医学院第一附属医院，河南省新乡市 453100
  • 收稿日期:2016-01-07 出版日期:2016-02-19 发布日期:2016-02-19
  • 作者简介:王峰，男，1980年生，河南省邓州市人，汉族，2010年新乡医学院毕业，硕士，主治医师，主要从事关节、关节微创研究

Absorbable internal fixation materials in the repair of patellar transverse fractures

Wang Feng1, Jia Jin-ling2   

  1. 1Second Department of Orthopedics, Nanyang City Central Hospital, Nanyang 473000, Henan Province, China; 2First Affiliated Hospital of Xinxiang Medical University, Xinxiang  453100, Henan Province, China
  • Received:2016-01-07 Online:2016-02-19 Published:2016-02-19
  • About author:Wang Feng, Master, Attending physician, Second Department of Orthopedics, Nanyang City Central Hospital, Nanyang 473000, Henan Province, China

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摘要：

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文题释义：

骨折内固定可吸收材料：具有良好的生物相容性，对组织无刺激，可被人体完全吸收，在体内缓慢降解，强度逐渐降低，最终降解为二氧化碳和水。随着植入物的降解，反应逐渐转移至愈合的骨折面上，增加骨密度，防止骨质疏松，克服骨折愈合后的局部应力遮挡与再骨折。

可吸收螺钉的优点：免除了二次手术痛苦，减少住院费用；避免骨质疏松危险，解决应力遮挡问题；无金属刺激反应，不形成任何金属锈渍物；允许骨折局部产生微小活动；不会形成纤维小囊；创面感染机会小；不干扰磁性影像；手术操作简单。

 

背景：近几年来，各种可吸收内固定材料开始被积极应用于各种髌骨横断性骨折的临床治疗中。
目的：探讨可吸收内固定材料修复髌骨横断性骨折的效果。
方法：纳入102例新鲜髌骨横断性骨折患者，其中男62例，女40例，年龄(41.85±11.15)岁，按治疗方法分为2组，观察组(n=52)采用可吸收螺钉修复，对照组(n=50)采用改良张力带钢丝内固定修复。修复后12个月，进行Lysholm膝关节功能评分与评估，记录不良事件的发生情况。
结果与结论：修复后12个月，观察组膝关节功能评分与优良率均高于对照组(P均 < 0.05)，观察组有4例出现骨折移位，未出现内固定物对皮肤产生刺激等不良事件；对照组有2例出现骨折移位，5例出现内固定物对皮肤产生刺激或者内固定滑脱松动，对照组不良事件发生率高于观察组(P < 0.05)。结果表明，利用可吸收螺钉修复髌骨横断性骨折，可促进膝关节功能恢复，并具有良好的生物相容性。 
ORCID: 0000-0001-5400-3985(王峰)

关键词: 生物材料, 骨生物材料, 可吸收材料, 髌骨骨折, 横断性骨折, 内固定, 生物相容性

Abstract:

BACKGROUND: In recent years, all kinds of absorbable internal fixation materials have been used in the clinical treatment of patellar transverse fractures.
OBJECTIVE: To investigate the repairing effect of absorbable internal fixation materials on patellar transverse fractures.
METHODS: Totally 102 cases of fresh patellar transverse fractures were included 62 males and 40 females cases, with a mean age of (41.85±11.15) years, and according to treatment methods, they were divided into two groups: observation group (n=52) using absorbable screws for reconstruction and control group (n=50) using Kirschner wire repair. At 12 months after repair, Lysholm knee function score were measured and evaluated, and the occurrence of adverse events was recorded.
RESULTS AND CONCLUSION: The knee function score and excellent rate of the observation group were significantly higher than those of the control group (both P < 0.05). In the observation group, there were four cases of fracture displacement, but no skin irritation and other adverse events occurred; in the control group, there were two cases of nonunion and five cases of skin irritation or internal fixation loosening and slippage. Therefore, there was a higher incidence of adverse events in the control group compared with the observation group (P < 0.05). These experimental results show that the use of absorbable screws in the repair of patellar transverse fracture can promote the functional recovery of the knee joint, with good biocompatibility.