中国组织工程研究

中国组织工程研究 ›› 2014, Vol. 18 ›› Issue (47): 7545-7549.doi: 10.3969/j.issn.2095-4344.2014.47.001

• 组织工程骨及软骨材料 tissue-engineered bone and cartilage materials •    下一篇

骨填充网袋修复椎体后壁破损骨质疏松性椎体骨折：可有效防止骨水泥渗漏

白  明，银和平，李树文，杜志才   

  1. 内蒙古医科大学第二附属医院微创脊柱外科，内蒙古自治区呼和浩特市  010030
  • 修回日期:2014-10-19 出版日期:2014-11-19 发布日期:2014-11-19
  • 通讯作者: 银和平，主任医师，内蒙古医科大学第二附属医院微创脊柱外科，内蒙古自治区呼和浩特市 010030
  • 作者简介:白明，男，1981年生，内蒙古自治区呼和浩特市人，蒙古族，在读博士，主治医师，主要从事脊柱外科微创技术研究。

Bone filling mesh container for osteoporotic vertebral fractures with posterior vertebral wall breakage: it is effective for prevention of bone cement leakage

Bai Ming, Yin He-ping, Li Shu-wen, Du Zhi-cai   

  1. Department of Minimally Invasive Spine Surgery, Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010030, Inner Mongolia Autonomous Region, China
  • Revised:2014-10-19 Online:2014-11-19 Published:2014-11-19
  • Contact: Yin He-ping, Chief physician, Department of Minimally Invasive Spine Surgery, Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010030, Inner Mongolia Autonomous Region, China
  • About author:Bai Ming, Studying for doctorate, Attending physician, Department of Minimally Invasive Spine Surgery, Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010030, Inner Mongolia Autonomous Region, China

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摘要：

背景：椎体后凸成形治疗合并椎体后壁破裂的骨质疏松性椎体压缩性骨折能迅速缓解疼痛，但较易发生骨水泥渗漏，引起相关并发症。
目的：观察在椎体后凸成形治疗椎体后壁破损骨质疏松性椎体骨折中使用骨填充网袋预防骨水泥渗漏的作用。
方法：纳入40例骨质疏松性椎体压缩骨折患者，CT及MRI显示所有椎体后壁有不同程度破损，其中男19例21个椎体，女21例28个椎体，年龄50-87岁；对40例患者进行经皮椎体后凸成形治疗，治疗过程中采用骨填充网袋推送骨水泥，观察治疗前后患者目测类比评分变化、椎体高度恢复及骨水泥渗漏情况。
结果与结论：40例患者均顺利完成手术，无肺栓塞发生，无骨水泥渗漏，未出现脊髓和神经根损伤，并获得10-12个月随访。所有患者治疗后1周及治疗后3个月目测类比评分、椎体中柱高度均较治疗前明显改善(P < 0.05)，治疗后3个月时与治疗后1周目测类比评分、椎体中柱高度比较差异无显著性意义(P > 0.05)。结果表明椎体后凸成形中使用骨填充网袋治疗椎体后壁破损的骨质疏松性椎体骨折可有效防止骨水泥渗漏。


中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程


全文链接：

关键词: 生物材料, 骨生物材料, 经皮椎体后凸成形, 骨质疏松性椎体压缩性骨折, 骨水泥, 渗漏, 骨填充网袋

Abstract:

BACKGROUND: Percutaneous kyphoplasty for osteoporotic vertebral fractures with posterior vertebral wall breakage can relieve pain rapidly, but there is a risk of leakage of bone cement.
OBJECTIVE: To observe the effect of bone filling mesh container in percutaneous kyphoplasty for osteoporotic vertebral fractures with posterior vertebral wall breakage.
METHODS: Forty senile patients with osteoporotic vertebral compression fractures were enrolled, whose CT and MRI showed different degrees of posterior vertebral wall breakage, including 19 males (21 vertebral bodies) and 21 females (28 vertebral bodies), aged 50-87 years. These 40 patients were subjected to percutaneous kyphoplasty, and bone filling mesh container was used to deliver bone cement. Then, changes in visual analogue scale score, vertebral height and leakage of bone cement were observed in patients before and after treatment.
RESULTS AND CONCLUSION: The surgery was successful in all the 40 patients, and no pulmonary embolism, cement leakage, and spinal cord and nerve root injuries appeared. All the patients were followed for 10-12 months. The visual analogue scale scores and vertebral height were improved significantly at both 1 week and 3 months after treatment compared with those before treatment, but there was no difference in the visual analogue scale scores and vertebral height at 1 week and 3 months after treatment. These findings indicate that percutaneous kyphoplasty with bone filling mesh container is effective to prevent bone cement leakage.


中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程


全文链接：

Key words: kyphoplasty, osteoporotic fractures, biocompatible materials

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