中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (35): 6550-6554.doi: 10.3969/j.issn.2095-4344.2012.35.018

• 骨科植入物 orthopedic implant • 上一篇    下一篇

后路椎弓根钉置入复合纳米人工骨植骨治疗胸腰椎骨折

黄旗凯，李 明，胡 文   

  1. 解放军第二军医大学长海医院骨科，上海市 200433
  • 收稿日期:2012-01-04 修回日期:2012-02-11 出版日期:2012-08-26 发布日期:2012-08-26
  • 通讯作者: 李明，教授，主任医师，博士生导师，解放军第二军医大学长海医院骨科，上海市 200433 limingch@21.com
  • 作者简介:黄旗凯★，男，1979年生，江西省抚州市人，汉族，2009年解放军第二军医大学大学在读硕士，主要从事脊柱外科的研究。 huangqikai@126.com

Posterior pedicle screw fixation combined with nanotechnology bone graft for the treatment of thoracolumbar fracture

Huang Qi-kai, Li Ming, Hu Wen   

  1. Department of Orthopedics, Changhai Hospital, Second Military Medical University of Chiese PLA, Shanghai 200433, China
  • Received:2012-01-04 Revised:2012-02-11 Online:2012-08-26 Published:2012-08-26
  • Contact: Li Ming, Professor, Chief physician, Doctoral supervisor, Department of Orthopedics, Changhai Hospital, Second Military Medical University of Chiese PLA, Shanghai 200433, China limingch@21.com
  • About author:Huang Qi-kai★, Studying for master’s degree, Department of Orthopedics, Changhai Hospital, Second Military Medical University of Chiese PLA, Shanghai 200433, China huangqikai@126.com

PDF

596

被引次数

3

摘要：

背景：纳米人工骨最大优点为具有骨诱导活性和优异的成骨性能并且可任意塑型，不良反应低。
目的：观察后路固定结合伤椎椎弓根纳米人工骨植骨治疗胸腰椎骨折疗效。
方法：48例胸腰椎骨折患者均在入院3 d内行后路椎弓根系统固定结合伤椎植入纳米人工骨治疗，分析对比治疗前后Cobb角，伤椎前缘高度及随访植骨融合。
结果与结论：所有病例均获得9个月以上随访。患者植入纳米人工骨后7 d及末次随访时Cobb角及伤椎前缘高较术前均有显著改善(P < 0.05)，末次随访与植入纳米人工骨后7 d上述指标比较差异无显著性意义(P > 0.05)，所有病例植骨均愈合良好。结果表明，后路椎弓根螺钉系统固定结合伤椎纳米人工骨植骨治疗胸腰椎骨折对维持重建脊柱稳定性及维持矫正率效果好，植骨融合率高，愈合快。

关键词: 纳米人工骨, 胸腰椎骨折, 内固定, Cobb角, 植骨融合

Abstract:

BACKGROUND: Nanotechnology bone has the advantages of osteoinductive activity and excellent osteogenic property, and it can be shaping with less adverse reactions.
OBJECTIVE: To observe the effect of posterior pedicle screw fixation combined with nanotechnology bone graft on the treatment of thoracolumbar fractures.
METHODS: Forty-eight thoracolumbar fracture patients were treated with posterior pedicle screw fixation combined with nanotechnology bone graft within 3 days after in hospital, the Cobb angel, the anterior vertebral height and bone healing before and after treatment were analyzed and compared.
RESULTS AND CONCLUSION: All patients were followed-up for over 9 months. At 7 days after nanotechnology bone implantation and the last follow-up, the Cobb angel and the anterior vertebral height were significantly improved compared with the pre-operation (P < 0.05), while there was no significant difference of the indexes (P > 0.05). All injured vertebral bone was healed well. For the treatment of thoracolumbar fractures, posterior pedicle screw fixation combined with nanotechnology bone graft has a good effect in maintaining the stability and the correction efficiency of reconstructed spine with high fusion rate and short healing time.

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