中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (16): 2949-2952.doi: 10.3969/j.issn.1673-8225.2011.16.023

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

滤膜材料及微滤技术的应用

许亚夫1，邹大江2，熊  俊1   

  1. 赣南医学院，1资产管理处，2信息工程学院，江西省赣州市  341000
  • 收稿日期:2011-01-04 修回日期:2011-03-14 出版日期:2011-04-16 发布日期:2013-11-11
  • 作者简介:许亚夫，男，1958年生，广东省汕头市人，2007年江西广播电视大学毕业，实验师，主要从事生物材料、实验材料、仪器设备保养维护等方面的研究。 songtao0601@yahoo.com.cn

Microfiltration membrane materials and techniques

Xu Ya-fu1, Zou Da-jiang2, Xiong Jun1   

  1. 1Asset Management Office, 2College of Information Engineering Gannan Medical College, Ganzhou  341000, Jiangxi Province, China
  • Received:2011-01-04 Revised:2011-03-14 Online:2011-04-16 Published:2013-11-11
  • About author:Xu Ya-fu, Experimentalist, Asset Management Office, Gannan Medical College, Ganzhou 341000, Jiangxi Province, China songtao0601@yahoo.com.cn

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918

被引次数

48

摘要：

背景：近年来，随着生物材料学的发展，微孔滤膜在其应用过程中，已逐步取代或提升了很多传统的过滤工艺，成为现代工业，尤其是高、精、尖端技术产业，如电子、生物制药、科学研究及质量检测等领域中保证产品质量不可缺少的重要手段之一，现代生物技术和制药工业发展的挑战加速了膜技术的进步。
目的：综述微滤技术的分离原理、特点、种类，介绍国内外滤膜材料的研究进展及其在各个领域中的应用。
方法：由第一作者于2011-03进行检索。检索中国全文期刊数据库(http://www.cnki.net/index.htm)及Pubmed数据库 (http://www.ncbi.nlm.nih.gov/sites/entrez/)1994-01/2010-12有关微滤技术、微滤材料的文章，检索词为“微滤技术，微滤膜，微孔滤膜”，文章语言种类为中文和英文，排除重复性研究。计算机初检得到60篇文章，阅读标题和摘要进行初筛，保留其中的20篇归纳总结，其中中文文献19篇，英文文献1篇。
结果与结论：微滤又称微孔过滤，它属于精密过滤，能够过滤微米级或纳米级的微粒和细菌。基本原理是筛分过程，依据膜孔径(或截留分子质量)的不同，可分为微滤膜、超滤膜、纳滤膜及反渗透膜。目前膜分离技术在各个方面的应用研究很活跃，但膜的污染、堵塞，原料液的黏度高，使膜通量衰减严重，无法继续分离，影响了膜分离在实际操作中迅速应用发展。要实现生物制品提纯的规模性应用，还要取决于相关方面的发展，如膜污染机制研究，对性能优良、抗污染膜材料的研究。将来多种类型的膜分离技术在生化产品应用中协同发展，取长补短，超滤、纳滤、微滤技术联用，实行多级分离是其发展趋势。

关键词: 微滤技术, 微孔滤膜, 生物材料, 膜分离技术, 过滤

Abstract:

BACKGROUND: In recent years, with the development of biomaterials, microfiltration membrane has been gradually instead of various traditional filtering techniques and become a indispensable way to ensure product quality in modern industry, especially high-grade, advanced technology industries, such as electronics, pharmaceuticals, scientific research and quality testing. The development of modern biotechnology and the pharmaceutical industry accelerates the development of membrane technology.
OBJECTIVE: To review the separation principle, characteristics, and types of microfiltration membranes and to introduce the development and application of microfiltration membrane in various fields.
METHODS: A retrieve of CNKI and PubMed were performed by the fist author to search articles about microfiltration membrane materials and techniques published from January 1994 to December 2010 by using the keywords of “microfiltration technique, microfiltration membrane, biomaterial” in Chinese and English. Repetitive articles were removed. Among 60 retrieved articles, 27 were included in result analysis, including 25 Chinese articles and 2 English.
RESULTS AND CONCLUSION: Microfiltration, also known as microporous filtration, belongs to delicate filtration, which can filter micron or nanoparticles and bacteria. The basic principle is based on different membrane pore size or molecular mass trapped, and the membranes can be classified as microfiltration membrane, ultrafiltration membrane, nanofiltration membrane and reverse osmosis membrane. Currently, the microfiltration technique is popular in every field, but membrane fouling, plugging, high viscosity of liquid material influence the rapid development of microfiltration membrane. The key to achieve the large-scale application of biological product purification depends on the studies on the mechanism of membrane fouling and anti-pollution film materials, and so on. In the future, a cooperative development among a variety of membrane separation techniques, such as ultrafiltration, nanofiltration and microfiltration will be realized, and the implementation of multi-stage separation is the developmental trend.

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