中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (50): 9447-.doi: 10.3969/j.issn.1673-8225.2010.50.034

• 组织构建学术探讨 • 上一篇    下一篇

心肌顿抑及运动的影响

陶小平1,2,苏全生3,李新建2   

  1. 1绍兴文理学院体育学院,浙江省绍兴市  312000; 2北京体育大学研究生院,北京市  100084;3成都体育学院医学系,四川省成都市  610041
  • 出版日期:2010-12-10 发布日期:2010-12-10
  • 通讯作者: 苏全生,博士,教授,成都体育学院医学系,四川省成都市 610041 bsutxp@sina.com
  • 作者简介:陶小平☆,男,1980年生,湖南省衡阳人,汉族,北京体育大学在读博士,讲师,主要从事运动人体科学和运动训练学的研究。 bsutxp@sina.com
  • 基金资助:

    论文属四川省科技厅项目(项目编号:2009J00001)部分研究成果,项目名称:中医药消除运动型疲劳的应用基础研究。

Effects of sports on myocardial stunning

Tao Xiao-ping 1,2, Su Quan-sheng 3, Li Xin-jian2   

  1. 1 Physical Education College, Shaoxing University, Shaoxing  312000, Zhejiang Province, China; 2 Graduate College of Beijing University of Physical Education, Beijing  100084, China; 3 Department of Medicine, Chengdu Sport University, Chengdu  610041, Sichuan Province, China
  • Online:2010-12-10 Published:2010-12-10
  • Contact: Su Quan-sheng, Doctor, Professor, Department of Medicine, Chengdu Sport University, Chengdu 610041, Sichuan Province, China bsutxp@sina.com
  • About author:Tao Xiao-ping☆, Studying for doctorate, Lecturer, Physical Education College, Shaoxing University, Shaoxing 312000, Zhejiang Province, China; Graduate College of Beijing University of Physical Education, Beijing 100084, China bsutxp@sina.com
  • Supported by:

    the Program of Sichuan Science and Technology Bureau, No.2009J00001*

摘要:

背景:随着体育科研领域研究的深入,运动对心脏的影响日益受到体育科研人员的关注和重视。
目的:系统综述心肌顿抑的研究历程、机制以及运动对顿抑心肌的影响。
方法:由第一作者检索PubMed数据库及维普数据库(1980-01/2010-01)的相关文章。英文检索词为“myocardial stunning; exercises;ischemia-reperfusion”,中文检索词为“心肌顿抑;运动;缺血再灌注”。计算机初步检索到83篇文献按纳入和排除标准筛选出36篇文献,从心肌顿抑的定义、特点、分类、机制以及运动对心肌顿抑影响等几方面出发进行归纳总结。
结果与结论:心肌顿抑在临床医学研究中越来越深入,心肌顿抑的定义、特点以及分类都很明确,并且也开始从分子生物学层面探索心肌顿抑的可能机制,然而剧烈运动持续时间过长,可引起运动员心肌灌流不足,导致心功降低和心肌损伤,由此可见,某种条件下,运动员可能出现心肌顿抑现象。

关键词: 心肌顿抑, 运动, 缺血再灌注, 能量代谢, 自由基

Abstract:

BACKGROUND: With the development with sports research, the effect of sports on heart has aroused increasing attention. 
OBJECTIVE: To systematic review myocardial stunning studies process, mechanism, and the relationship between exercise and myocardial stunning.
METHODS: This study was retrieved by the first author with the key words of “myocardial stunning, exercises, ischemia-reperfusion” in both English and Chinese (1980-01/2010-01) from PubMed databaseand Vip database. Totally 83 documents were initially searched by computer. A total of 36 articles were selected according to inclusive and exclusive criteria, and the papers were summarized from the aspects of definition, characteristics, classification, mechanism and effect on myocardial stunning.
RESULTS AND CONCLUSION: Myocardial stunning was clinical studied more and more deeply, the definition, characteristics and categories of myocardial stunning are clarified, and also began to explore the myocardial stunning possible mechanism in molecular biology level. However, long duration, vigorous exercise caused exercise athletes perfusion defect leading to reduced cardiac function and myocardial injury, the exercise myocardial stunning phenomenon should be possible.

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