中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (50): 9370-.doi: 10.3969/j.issn.1673-8225.2010.50.015

• 组织构建基础实验 • 上一篇    下一篇

减阻牵张快速牙齿移动的组织学变化

祁涛1，卢嘉静2，葛振林1，苏少晨3，杨彩霞1   

  1. 1兰州大学口腔医学院，甘肃省兰州市  730000；2泰州职业技术学院口腔系，江苏省泰州市  225300；3兰州大学第二医院，甘肃省兰州市 730000
  • 出版日期:2010-12-10 发布日期:2010-12-10
  • 通讯作者: 葛振林，副教授，兰州大学口腔医学院，甘肃省兰州市 730000 gezhl@lzu.edu.cn
  • 作者简介:祁涛★，男，1981年生，甘肃省酒泉市人，汉族，兰州大学口腔医学院在读硕士，主要从事口腔正畸学临床与基础方面的研究。 qit07@sohu.com
  • 基金资助:

    甘肃省自然科学基金项目(0710RJZA029)；兰州大学医学科研基金项目(LZUYX200705)。

Histological changes of periodontal ligament during rapid tooth movement through reducing resistance and distraction 

Qi Tao1, Lu Jia-jing2, Ge Zhen-lin1, Su Shao-chen3, Yang Cai-xia1   

  1. 1 School of Stomatology, Lanzhou University, Lanzhou  730000, Gansu Province, China; 2 Department of Stomatology, Taizhou Polytechnic College, Taizhou  225300, Jiangsu Province, China; 3 Department of Stomatology, Second Hospital of Lanzhou University, Lanzhou  730000, China
  • Online:2010-12-10 Published:2010-12-10
  • Contact: Ge Zhen-lin, Associate professor, School of Stomatology, Lanzhou University, Lanzhou 730000, Gansu Province, China gezhl@lzu.edu.cn
  • About author:Qi Tao★, Studying for master’s degree, School of Stomatology, Lanzhou University, Lanzhou 730000, Gansu Province, China qit07@sohu.com
  • Supported by:

     the Natural Science Foundation of Gansu Province, No. 0710RJZA029*; Science and Technology Foundation of Medical Department of Lanzhou University, No. LZUYX200705*

PDF

409

被引次数

5

摘要：

背景：采用降低牙移动路径上的骨阻力和强持续牵张力能快速移动正畸牙，缩短正畸疗程，但移动牙组织变化规律目前尚不清楚。

目的：观察减阻牵张法快速移动牙齿的牙周组织学变化。 

方法：采用自身对照设计，以犬一侧下颌为实验侧，另一侧为对照侧，拔除下颌第二前磨牙，实验侧采用减阻牵张法，对照侧采取传统正畸方法，远移第一前磨牙。加力后2周，测量移动牙及支抗牙移动距离；加力后1，2，4，12 周观察牙周膜、牙槽骨的组织学变化。

结果与结论：加力后1~4周，实验侧和对照侧移动牙张力侧均表现为牙周膜增宽，成骨活跃，牙槽骨表面有新骨生成；压力侧均表现为牙周膜缩窄，破骨细胞活跃，牙槽骨有明显吸收，牙骨质也有不同程度吸收；但是，实验侧成骨细胞和破骨细胞出现均早于对照侧，牙槽骨及牙骨质吸收程度较对照侧严重。12周时，实验侧和对照侧牙周组织表现无明显差别。而加力2周，实验侧牙齿移动距离明显大于对照侧(P < 0.05)。说明减阻牵张法可以快速移动牙齿；与传统正畸牙移动相比，两者牙周组织的改建只存在时间及程度的差异，不存在质的差别。

关键词: 减阻牵张, 快速移动牙齿, 组织学, 牙周膜, 成骨细胞, 破骨细胞

Abstract:

BACKGROUND: Rapid movement of orthodontic tooth can be achieved with the method of reducing resistance and distraction. However, the histological changes of the periodontal ligament during orthodontic tooth movement are not yet very clear.
OBJECTIVE: To observe the histological changes of periodontal ligament during rapid tooth movement through reducing resistance and distraction.
METHODS: A self-control design was employed. The second premolars on both sides were extracted and one side was randomly selected as experimental side and the other as control side. The first premoalrs were distalized respectively using the method of reducing resistance and distraction on the experimental side and traditional methods on the control side. The distance of the tooth movement was measured at the end of 2nd week after the activation. The animals were sacrificed at 1, 2, 4 and 12 weeks after the activation. The periodontal ligament histological changes of moving tooth were observed by a light microscope.
RESULTS AND CONCLUSIONS: The method of reducing resistance and distraction accelerated the periodontal ligament remodeling and alveolar bone absorbing (pressure side), new born growing (tension side). There was no significantly difference between the pressure side and the tension side of experimental moved teeth and control moved teeth at 12 weeks groups. The average distal movements of moved teeth by the experimental side were significantly greater than control side at 2 weeks (P < 0.05). There was no difference in quality but in quantity on the histological reactions of the tooth moved by traditional method and by the method of reducing resistance and distraction, the latter could accelerated tooth movement than the former.

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