中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (47): 8881-8884.doi: 10.3969/j.issn.1673-8225.2010.47.035

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

人工材料聚丙烯补片在修补腹壁切口疝中的应用

郭盛旗   

  1. 河南省获嘉县徐营镇卫生院普外科,河南省新乡市     453832
  • 出版日期:2010-11-19 发布日期:2010-11-19
  • 作者简介:郭盛旗,男,1965年生,河南省获嘉县人,汉族,1996年新乡医学院毕业,主治医师,主要从事普外科方面的研究。 guoshengqi88@163.com

Application of polypropylene patch in repair of abdominal wall incisional hernia

Guo Sheng-qi     

  1. Department of General Surgery, Public Health Center of Xuying Town, Huojia County, Xinxiang   453832, Henan Province, China
  • Online:2010-11-19 Published:2010-11-19
  • About author:Guo Sheng-qi, Attending physician, Department of General Surgery, Public Health Center of Xuying Town, Huojia County, Xinxiang 453832, Henan Province, China guoshengqi88@163.com

摘要:

背景:如何修补腹壁巨大缺损是临床经常遇到的难题,曾有许多学者尝试各种材料进行修补,但临床效果不是很满意。
目的:检索文献综合分析人工聚丙烯补片在修补腹壁切口疝中的应用效果。
方法:应用计算机检索检索Pubmed 数据库(http://www.ncbi.nlm.nih.gov/pubmed/)及万方数据库(http://www. wanfangdata.com.cn)1991-01/2009-12的相关文献,在标题和摘要中以“补片,外科手术,腹壁切口疝”或“patch,surgery,incisional hernia”为检索词进行检索。选择与人工材料聚丙烯补片在修补腹壁切口疝中的应用相关,同一领域文献则选择近期发表或发表在权威杂志文章。最终纳入符合标准的文献28篇。
结果与结论:临床常需要借助合适的材料来修复巨大的腹壁缺损,以维持腹壁的肌张力和外形。聚丙烯补片具有良好的生物相容性,置入体内后不会导致创口感染、排异反应及其他并发症,具有较理想的预防游离腹直肌皮瓣术后切口疝发生的作用,同时也增强了腹壁强度。临床研究表明其组织相容性良好,无排异反应,具有一定抗感染能力,是理想的疝修补材料。提示应用人工合成材料进行疝修补,操作简便、损伤小、恢复快、复发率低,并发症少。但提高修补技术,选择并研制抗张力强度大、炎症反应轻、顺应性高的补片仍是该领域研究的重点。

关键词: 切口疝, 腹壁, 无张力修补, 聚丙烯补片, 生物相容性

Abstract:

BACKGROUND: How to repair large defects in abdominal wall is a frequently encountered clinical problem, many scholars have tried to repair using a variety of materials, but the clinical effect is not very satisfactory.
OBJECTIVE: To comprehensively analyze the literatures about the application of artificial polypropylene patch to repair the abdominal wall incisional hernia.
METHODS: A computer-based search of Pubmed database (http://www.ncbi.nlm.nih.gov/pubmed/) and Wanfang database (http://www.wanfangdata.com.cn) between January 1991 and December 2009 was performed, by screening “patch, surgery, incisional hernia” in English and in Chinese as key words to search the titles and abstracts. Articles related to the artificial material polypropylene patch in repair of abdominal incisional hernia were selected, those recently published literatures or published in the authority journal were preferred in the same field. Eventually 28 articles met the criteria were involved.
RESULTS AND CONCLUSION: The large abdominal wall defects often require clinical use of appropriate materials, in order to maintain muscle tension and shape of the abdominal wall. Polypropylene patch has good biocompatibility, and no wound infection, rejection and other complications occur after implantation, the patch is effective to prevent postoperative incisional hernia of free transverse rectus abdominis myocutaneous flap, while enhancing abdominal walll strength. Clinical studies have shown its good tissue compatibility, no rejection, certain resistance to infection, is the ideal material of hernia repair. Hernia repair using artificially synthetic materials is easy to operate, with less damage, quick recovery, low recurrence rate and few complications. The key of related study should focus on the increase of repair techniques, selection and development of the patch with great resistant to tensile strength, mild inflammation, and high compliance.

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