中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (44): 8303-8306.doi: 10.3969/j.issn.1673-8225.2010.44.033

• 器官移植学术探讨 academic discussion of organ transplantation • 上一篇    下一篇

肝移植后肺部感染的因素及防治策略

丁利民，时  军   

  1. 江西省人民医院，江西省南昌市    330006
  • 出版日期:2010-10-29 发布日期:2010-10-29
  • 通讯作者: 时军，博士，教授，硕士生导师，主任医师，江西省人民医院，江西省南昌市 330006 shijun6207@163.com
  • 作者简介:丁利民★，男，1983年生，江西省崇仁县人，汉族，南昌大学医学院在读硕士，主要从事器官移植及普通外科的研究。 dinglimin1203@163.com

Factors and control strategies for pulmonary infection following liver transplantation

Ding Li-min, Shi Jun   

  1. Jiangxi Provincial People’s Hospital, Nanchang  330006, Jiangxi Province, China
  • Online:2010-10-29 Published:2010-10-29
  • Contact: Shi Jun, Doctor, Professor, Master’s supervisor, Chief physician, Jiangxi Provincial People’s Hospital, Nanchang 330006, Jiangxi Province, China shijun6207@163.com
  • About author:Ding Li-min★, Studying for master’s degree, Jiangxi Provincial People’s Hospital, Nanchang 330006, Jiangxi Province, China dinglimin1203@163.com

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摘要：

背景：尽管肝移植已经取得了很大进展，但移植后感染仍是威胁生命的主要问题，其中肺部感染是肝移植患者最常见的感染性并发症，也是导致移植后患者死亡的主要原因之一。
目的：就近年来肝移植后肺部感染的临床研究做一综述，为肝移植后肺部感染的治疗提供临床参考意见。
方法：由第一作者检索1995/2009 SPRINGER数据库 (http://springer.lib.tsinghua.edu.cn/home/main.mpx)及中国期刊全文数据库(http://dlib.cnki.net/kns50/)有关肝移植后肺部感染的易感因素、常见病原体、预防及治疗措施的文献，英文检索词为“liver transplantation，pulmonary infection，treatment”，中文检索词为“肝移植，肺部感染，治疗”。排除重复性研究。
结果与结论：计算机初检得到217 篇文献，最终纳入29篇文献进一步分析。结果提示肝移植后肺部感染的合理预防、早期诊断和及时处理，对于提高肝移植效果至关重要。肝移植临床医生应根据本地区、本单位致病微生物流行病学特点及实际医疗条件结合每个患者的具体情况，及时修正诊断与治疗，制定合理的预防与治疗方案。
　

关键词: 肝移植, 肺部感染, 易感因素, 预防, 治疗

Abstract:

BACKGROUND: Liver transplantation has gained remarkable development, but infection after transplantation is the main reason which threatens the patient’s life. Pulmonary infection is the most common infectious complications after liver transplantation, which is one of the important reasons that cause the death of the patient.
OBJECTIVE: Based on the overview of progress regarding the clinical research of pulmonary infection after liver transplantation for the past few years, to provide the clinical advices for further research on treating the pulmonary infection after liver transplantation.
METHODS: The databases of SPRINGER (http://springer.lib.tsinghua.edu.cn/home/main.mpx) and CNKI (http://dlib.cnki.net/kns50/) were retrieved by the first author with key words of “liver transplantation, pulmonary infection, treatment” in both Chinese and English from 1995 to 2009. The repetitive studies were excluded.
RESULTS AND CONCLUSION: Total 217 articles were gotten by computers according to criteria, 29 articles of which were included in the final analysis. The results demonstrated that, reasonable prevention, early diagnosis and timely treatment of pulmonary infection play an important role in elevating outcomes of liver transplantation. The clinical doctor should modify diagnosis and treatment for patients according to characteristics of pathogenic microorganism epidemiology in local area combine with individuals, more importantly, constitute schemes of prevention and treatment reasonably based on practice medicine conditions.

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