中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (42): 7935-7938.doi: 10.3969/j.issn.1673-8225.2010.42.035

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

网状平片生物补片在腹股沟疝修复中的应用

郭盛旗   

  1. 河南省获嘉县徐营镇卫生院普外科,河南省新乡市 453832 
  • 出版日期:2010-10-15 发布日期:2010-10-15
  • 作者简介:郭盛旗,男,1965年生,河南省获嘉县人,汉族,1996年新乡医学院毕业,主治医师,主要从事普外科方面的研究。 GUOSHENGQI88@163.com

Mesh plain biological patch in inguinal hernia repair

Gao Sheng-qi   

  1. Department of General Surgery, Public Health Center of Xuying Town, Huojia County, Xinxiang   453832, Henan Province, China
  • Online:2010-10-15 Published:2010-10-15
  • About author:Guo Sheng-qi, Attending physician, Department of General Surgery, Public Health Center of Xuying Town, Huojia County, Xinxiang 453832, Henan Province, China GUOSHENGQI88@163.com

摘要:

目的:探讨网状平片生物补片在腹股沟疝修复中的应用。
方法:应用计算机检索PubMed数据库(http://www.ncbi.nlm.nih.gov/PubMed)及CNKI数据库(www.cnki.net/index.htm),在标题和摘要中以“补片,外科手术,腹股沟疝”或“patch,Surgery,Inguinal hernia”为检索词进行检索。选择文章与检索关键词材料学特点、生物相容性及其应用效果相关,同一领域文献则选择近期发表或发表在权威杂志文章。共纳入25篇文献。
结果:根据疝修补材料的化学成分和生物学特性,可以将疝修补材料分为不可吸收材料、可吸收材料、复合型修补材料及生物型材料。不可吸收性材料在修补材料中所占比重较大,并有金属和非金属之分。这些材料都表现出良好的生物相容性,具有抗张力强度大,耐受力强,植入体内无明显异物感等优点。无张力疝修补术所使用的补片能够刺激周围组织发生快速的成纤维细胞反应,恢复并加强修补部位的组织强度,较之以往以改变腹股沟管解剖结构为前提的各种张力性缝合修补术更合理、更可靠,杜绝了疝复发的解剖学基础。临床研究表明平面补片组织相溶性良好,无排异反应,具有一定抗感染能力,是理想的腹股沟疝修补材料。
结论:应用网状平片行无张力疝修补术治疗腹股沟疝是一种较好的术式,具有手术安全、复发率低,创伤小,并发症少等优点。

关键词: 腹股沟, 疝, 无张力修补, 外科手术, 补片

Abstract:

OBJECTIVE: To investigate the application of biological mesh plain patch in the repair of inguinal hernia.
METHODS: A computer search of PubMed database (http://www.ncbi.nlm.nih.gov/PubMed) and CNKI database (www.cnki.net/index.htm) was performed by screening “patches, surgery, inguinal hernia" in English and in Chinese as key words in the titles and summaries. Articles related to the material science characteristics, biocompatibility and application effect were included, those published recently or published in the authority journal were preferred in the same field. Totally 25 literatures were involved.
RESULTS: According to chemical compositions and biological characteristics, hernia repair materials can be divided into unabsorbable materials, absorbable materials, composite repair materials and bio-based materials. Unabsorbable materials are predominant in the repair materials, and include metal and nonmetal materials. These materials have good biocompatibility, great tensile strength, strong tolerance, no foreign body sensation after implantation. Tension-free hernia repair patch can stimulate the rapid fibroblast response of surrounding tissues, restore and enhance the tissue strength in repair parts, it is more reasonable and more reliable than all kinds of tension suture repair, which takes the altered anatomical structure of the inguinal canal as the prerequisite, and prevents the anatomical basis of hernia recurrence. Clinical research shows that plain patch has well histocompatibility, no rejection, and certain resistance to infection, it is the ideal material of inguinal hernia repair.
CONCLUSION: Tension-free repair treatment of inguinal hernia using mesh plain patch is a good surgical approach, with surgical safety, low recurrence rate, little trauma, and few complications.

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