关键词: 有氧运动, SD大鼠, 无氧运动, 肌浆网, Na⁺ , K⁺ -ATP酶, Ca ²⁺ -ATP酶

Abstract:

BACKGROUND: Na⁺ , K+-ATPase and Ca ²⁺-ATPase play an important role in substances transportation, energy conversion and information transfer. The sarcoplasmic reticulum plays a key role in muscle excitation contraction coupling, which closely relates to exercise-induced muscular fatigue.
OBJECTIVE: To establish SD rat models of aerobic exercise and anaerobic exercise, and to observe the effects of exercise training at different work intensities on the activity of Na⁺, K⁺ -ATPase and Ca ²⁺ -ATPase in skeletal muscle sarcoplasmic reticulum.
METHODS: According to BEDFORD TG standards, motion models were established using treadmill running with different work intensities. The aerobic exercise group applied incremental exercise, the anaerobic exercise group treated with high-speed interval training, and rats in control group lived in the cages quietly. All the animals were killed immediately when the exercise training completed. Then the skeletal muscle sarcoplasmic reticulum were isolated by ultracentrifugation to measure their Na⁺ , K⁺ -ATPase and Ca ²⁺-ATPase activities. 
RESULTS AND CONCLUSION: The activity of Na⁺, K⁺ -ATPase and Ca ²⁺-ATPase increased significantly after 4 weeks’ training (P < 0.05). By 6 weeks’ training, Na⁺ , K⁺-ATPase and Ca ²⁺-ATPase’s activity were increased only in the anaerobic exercise group (P < 0.05), which were decreased in the anaerobic exercise group (P < 0.05). The present findings demonstrated that, aerobic exercise can protect the activity of Na⁺ , K⁺-ATPase and Ca ²⁺ -ATPase of skeletal muscle sarcoplasmic reticulum, but it needs some time to adapt.