中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (20): 3730-3733.doi: 10.3969/j.issn.1673-8225.2010.20.028

• 组织构建细胞学实验 cytology experiments in tissue construction • 上一篇    下一篇

实验动物臂丛神经的拉伸力学特性

沈 哲1，孙长江2，冯铁键3，马洪顺4   

  1. 1深圳市第二人民医院骨科，广东省深圳市518053；
    2吉林大学中日联谊医院，吉林省长春市  130031；
    3吉林大学南岭校区医院，吉林省长春市  130022；
    4吉林大学南岭校区工程力学系，吉林省长春市  130022
  • 出版日期:2010-05-14 发布日期:2010-05-14
  • 通讯作者: 马洪顺，教授，吉林大学南岭校区工程力学系，吉林省长春市 130022 mahs@jlu.edu.cn
  • 作者简介:沈 哲，男，1973年生，汉族，吉林省长春市人，2008年吉林大学毕业，博士，主治医师，主要从事骨科临床与生物力学研究。 mahs@jlu.edu.cn

Tensile mechanical properties of the brachial plexus of experimental animals

Shen Zhe1, Sun Chang-jiang2, Feng Tie-jian3, Ma Hong-shun4   

  1. 1 Department of  Orthopaedics, Shenzhen Second People’s Hospital, Shenzhen  518053, Guangdong Province, China;
    2China-Japan Union Hospital of Jilin University, Changchun  130031, Jilin Province, China;  
    3Nanling Campus Hospital of Jilin University, Changchun  130022, Jilin Province, China;
    4Department of Engineering Mechanics, Nanling Campus of Jilin University, Changchun  130022, Jilin Province, China
  • Online:2010-05-14 Published:2010-05-14
  • Contact: Ma Hong-shun, Professor, Department of Engineering Mechanics, Nanling Campus of Jilin University, Changchun 130022, Jilin Province, China mahs@jlu.edu.cn
  • About author:Shen Zhe, Doctor, Attending physician, Department of Orthopaedics, Shenzhen Second people’s Hospital, Shenzhen 518053, Guangdong Province, China

PDF

560

被引次数

24

摘要：

背景：臂丛神经损伤缝合吻接术有必要了解臂丛神经拉伸力学特性。

目的：对大鼠臂丛神经进行拉伸实验，观察其臂丛神经的拉伸力学特性，为临床提供拉伸力学特性参数。

方法：取SD大鼠C6~7臂丛神经40个，随机分为正常对照组20个，模拟臂丛神经损伤吻接组20个，对模拟臂丛神经损伤吻接组以手术刀在标本中间切开再缝合吻接离断标本。在电子万能试验机上以5 mm/min的实验速度对2组标本进行拉伸实验，以多项式用最小二乘法处理实验数据。拉伸实验速度为5 mm/min。观察大鼠臂丛神经拉伸最大载荷、最大位移、最大应变、最大应力和应力-应变曲线。

结果与结论：模拟臂丛神经损伤吻接组大鼠臂丛神经拉伸最大载荷为(1.050±0.135) N、最大位移为(3.090±0.356) mm、最大应变为(61.860±7.252)%、最大应力为(5.095±0.647) GPa，正常对照组最大载荷、最大应力大于模拟丛神经损伤吻接组(P < 0.05)。模拟臂丛神经损伤吻接组最大位移和最大应变大于正常对照组(P < 0.05)。拉伸应力-应变曲线是以指数关系变化的。结果显示2组臂丛神经标本具有不同的拉伸力学特性。

关键词: 臂丛神经, 拉伸实验, 最大载荷, 最大位移, 最大应变, 最大应力, 大鼠, 神经组织工程

Abstract:

BACKGROUND: It is necessary to understand the brachial plexus stretch mechanical properties for the brachial plexus injuries suture anastomosis technique.

OBJECTIVE: The brachial plexus of laboratory animals was performed tensile experiment to observe the tensile mechanical properties, which can provide the tensile mechanical properties parameters for the clinic.

METHODS: A total of 40 C6-7 brachial plexus of rats were obtained and randomly divided into the normal control group (n = 20) and analog brachial plexus injury anastomosis group (n = 20). The middle of the specimen was cut off from the broken suture by hand-cut way to the analog brachial plexus injury anastomosis. Tensile test with the speed of 5 mm/min was performed, and the experimental data was treated by using the polynomial and Least-squares method. The tensile maximum load, maximum displacement, maximum strain, maximum stress, and stress-strain curve were observed.

RESULTS AND CONCLUSION: The tensile maximum load of the analog brachial plexus injury anastomosis group was (1.050±0.135) N, maximum displacement was (3.090±0.356) mm, maximum strain was (61.860±7.252)%, and maximum stress was (5.095±0.647) MPa. The tensile maximum load and the maximum stress of the normal control group were greater than those of the analog brachial plexus injury anastomosis group (P < 0.05), but the maximum displacement and maximum strain were smaller than the analog brachial plexus injury anastomosis group (P < 0.05). The tensile stress-strain curve is changed in exponential relationship. The results demonstrated that the two groups of brachial plexus tensile specimens have different mechanical properties.

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