中国组织工程研究

中国组织工程研究 ›› 2022, Vol. 26 ›› Issue (15): 2412-2418.doi: 10.12307/2022.600

• 骨与关节综述 bone and joint review • 上一篇    下一篇

膝关节有限元分析的研究热点及趋势

李志帅1，2，张红倩3，李  丽1，2，韩新文1，2，冯  静3   

  1. 1青岛滨海学院附属医院，山东省青岛市   266404；2青岛滨海学院医学院，山东省青岛市   266555；3潍坊医学院康复医学院，山东省潍坊市   261053
  • 收稿日期:2021-07-21 修回日期:2021-09-13 接受日期:2021-10-26 出版日期:2022-05-28 发布日期:2022-01-06
  • 通讯作者: 李丽，博士，主治医师，青岛滨海学院附属医院康复医学科，山东省青岛市 266404
  • 作者简介:李志帅，女，1987年生，山东省潍坊市人，汉族，2015年上海交通大学毕业，硕士，主治医师，主要从事运动医学的研究。 张红倩，女，1994年生，贵州省安龙县人，汉族，潍坊医学院2019级在读硕士。
  • 基金资助:
    山东省医药卫生科技发展计划项目(202020011232)，项目负责人：李丽；山东省高等学校青创人才引育计划康复治疗学研究创新团队项目；山东省医药卫生科技发展计划项目(202020011222)，项目负责人：李志帅

Finite element analysis of the knee joint: research hotspots and trends

Li Zhishuai1, 2, Zhang Hongqian3, Li Li1, 2, Han Xinwen1, 2, Feng Jing3   

  1. 1The Affiliated Hospital of Qingdao Binhai University, Qingdao 266404, Shandong Province, China; 2Medical School of Qingdao Binhai University, Qingdao 266555, Shandong Province, China; 3School of Rehabilitation Medicine, Weifang Medical University, Weifang 261053, Shandong Province, China
  • Received:2021-07-21 Revised:2021-09-13 Accepted:2021-10-26 Online:2022-05-28 Published:2022-01-06
  • Contact: Li Li, MD, Attending physician, the Affiliated Hospital of Qingdao Binhai University, Qingdao 266404, Shandong Province, China; Medical School of Qingdao Binhai University, Qingdao 266555, Shandong Province, China
  • About author:Li Zhishuai, Master, Attending physician, the Affiliated Hospital of Qingdao Binhai University, Qingdao 266404, Shandong Province, China; Medical School of Qingdao Binhai University, Qingdao 266555, Shandong Province, China Zhang Hongqian, Master candidate, School of Rehabilitation Medicine, Weifang Medical University, Weifang 261053, Shandong Province, China Li Zhishuai and Zhang Hongqian contributed equally to this work.
  • Supported by:
    Medical and Health Science and Technology Development Project of Shandong Province, No. 202020011232 (to LL); Rehabilitation Therapeutics Research Innovation Team Project of College Youth Innovation Talent Introduction and Culture Plan of Shandong Province; Medical and Health Science and Technology Development Project of Shandong Province, No. 202020011222 (to LZS)

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摘要：

文题释义：
CiteSpace：是美国德雷克塞尔大学陈超美博士团队利用Java语言开发，具有“图”和“谱”的双重性质与特征，能够将一个知识领域的演进历程集中展现于引文网络图谱，并自动标识图谱上作为知识基础的引文节点文献和共引聚类所表征的研究前沿。
有限元分析：是一种理论生物力学的研究方法，其“标本”是建立的虚拟计算机模型，将工程系统的数学行为代入到模型中进行数值力学的分析，可以通过调整数据来改变模型或是力学加载情况，重新测得各组成结构的应力和位移变化，可获取全域性的信息。

背景：有限元分析以其可视化、无创性等特点在膝关节中的应用日益广泛，国际上对该领域的研究逐年递增，有限元模型成果丰硕，且逐渐多元化。但对于膝关节有限元分析的研究现状、热点、趋势较为缺乏。
目的：利用可视化分析方法探索近10年有限元技术应用于膝关节的研究现状、热点及趋势。
方法：以Web of Science核心合集为数据来源，检索2011-2020年以有限元分析与膝关节为主题的相关文献，运用citespace5.7.R2软件对有限元分析在膝关节应用的相关研究进行科学知识图谱分析和文献梳理。
结果与结论：①去重后共纳入1 026篇文献，近10年该领域发文量及被引频次逐年增长，被引频次总计达11 088次。②共256种期刊发表了该领域相关文章，收录期刊研究领域集中于生物物理学、工程学、计算机科学、矫形外科学，其中发文量最高的期刊为《JOURNAL OF BIOMECHANICS》。③共有62个国家、328个机构、342个作者发表该领域的相关研究，发文数量排名前3的国家依次是美国、中国、英格兰；发文量前3个机构为韩国的延世大学、韩国延世Sarang医院、东芬兰大学，其中KYOUNGTAK KANG教授团队发文量最多。④关键词分析表明，有限元分析在膝关节应用研究内容主要集中在关节软骨、骨关节炎、膝关节置换、半月板切除、生物力学及组件研究等方面，近4年来膝关节损伤修复、单髁置换、轴线不对称等方向成为研究前沿。⑤膝关节有限元分析的相关研究方向在10年来由最初的基础实验研究，逐渐向以临床决策为导向的科研角度发展，研究内容从模型的建立、优化和验证等方面转向对手术假体、入路及修复材料等方面的研究，而对材料/假体性能、辅助膝关节置换/移植等修复技术发展的研究将成为该领域今后的发展趋势。

https://orcid.org/0000-0003-0551-824X (李志帅)

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

关键词: 有限元分析, 有限元模型, 膝关节, citespace, 可视化分析, 生物力学, 置换, 修复

Abstract: BACKGROUND: Finite element analysis has been widely used in the knee joint due to its visualization and noninvasion. International research in this field has been increasing year by year, and the finite element analysis model has achieved fruitful results and gradually diversified. However, less is reported on the research status, hot spots and trends of finite element analysis of the knee joint.
OBJECTIVE: To analyze the current research status, hot spots and trends of finite element technology used in the knee joint in recent 10 years using visual analysis method.
METHODS: The core collection of Web of Science was used as the data source to search for relevant literature on the subject of finite element analysis and knee joints from 2011 to 2020. CiteSpace.5.7.R2 software was used to conduct scientific knowledge map analysis and literature review on the research related to the application of finite element technology in the knee joint. 
RESULTS AND CONCLUSION: After deduplication, a total of 1 026 articles were included. In the past 10 years, the number of published papers and citation  frequency in this field has increased year by year, with a total of 11 088 citations. A total of 256 journals have published articles related to this field. The research fields of the included journals are concentrated in biophysics, engineering, computer science, and orthopedic surgery. JOURNAL OF BIOMECHANICS published the most papers in this field. A total of 328 institutions and 342 authors from 62 countries have published related studies. The top three countries with the most publications are the United States, China, and England in sequence. The top three institutions with the most publications are Yonsei University and Yonsei Sarang Hospital in South Korea, and the University of Eastern Finland. Professor Kyoungtak Kang’s team has the largest number of publications. Key word analysis shows that the finite element analysis in knee joint research mainly focuses on articular cartilage, osteoarthritis, knee replacement, meniscus resection, biomechanics, component research, etc. In the past 4 years, knee revision, unicompartmental knee arthroplasty, and malalignment have become frontier issues. The research direction has gradually developed from the initial experimental research to the clinical decision-oriented research in the past 10 years. The research content has shifted from the establishment, optimization, and verification of models to the exploration of surgical prostheses, surgical approaches, and repair materials. Research on the development of materials/prosthesis performance, auxiliary knee arthroplasty/implantation and other repair technologies will become the future development trend in this field.

Key words: finite element analysis, finite element model, knee joint, citespace, visual analysis, biomechanics, replacement, revision

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