Chinese Journal of Tissue Engineering Research ›› 2020, Vol. 24 ›› Issue (16): 2614-2619.doi: 10.3969/j.issn.2095-4344.2293

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Network Meta-analysis of five common dressings in the treatment of pressure ulcer

Huang Ruina1, Huang Ruijia2, Niu Caili3, Wen Junmao4, Liu Wanjun4, Han Hui4, Tian Ting4, Wu Xiaowan4   

  1. 1Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen 518033, Guangdong Province, China; 2Department of Reproductive Medicine, the First Affiliated Hospital of Shantou University Medical College, Shantou 515031, Guangdong Province, China; 3Guangzhou University of Traditional Chinese Medicine Shenzhen Hospital, Shenzhen 518033, Guangdong Province, China; 4Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405, Guangdong Province, China
  • Received:2018-08-17 Revised:2018-08-18 Accepted:2018-10-10 Online:2020-06-08 Published:2020-03-28
  • Contact: Wu Xiaowan, Professor, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405, Guangdong Province, China
  • About author:Huang Ruina, Nurse, Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen 518033, Guangdong Province, China
  • Supported by:
    Guangdong Provincial Special Fund for Traditional Chinese Medicine Construction, No. 20181083

Abstract:

BACKGROUND: There are many kinds of dressings for external use in treating pressure ulcer. Selecting a kind of dressing which is convenient, safe and effective can effectively increase the healing rate of pressure ulcer. 

OBJECTIVE: To evaluate the effects of five common dressings on the treatment of pressure ulcer. 

METHODS: A systematic search of Embase, PubMed, VIP, Elsevier, WanFang and CNKI were carried out with an end-point of July 2018. Randomized controlled trials about the therapeutic effects of different dressings on pressure ulcer were collected. All data were screened, extracted and assessed by two researchers independently. The ADDIS 1.16.8 software was adopted for data analysis. 

RESULTS AND CONCLUSION: A total of 24 randomized control trials (1201 patients) which involved 5 kinds of dressings were included. The results of network Meta-analysis showed that the effect of hydrocolloid dressing and foam dressing were superior to aseptic gauze and vaseline gauze in treating pressure ulcer (P < 0.05). There was no difference in the therapeutic effect between the resting dressings (P > 0.05). Based on the probability ranking table, the therapeutic effects of five kinds of dressings in pressure ulcer were ranked as follows: hydrocolloid dressing > foam dressing > hydrogel dressing > sterile gauze > vaseline gauze. Hydrocolloid dressing and foam dressing were superior to the other dressings in the treatment of pressure ulcer.

Key words: pressure ulcer, dressing, hydrocolloid dressing, foam dressing, hydrogel dressing, network meta-analysis, biomaterial

CLC Number: