中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (18): 3349-3356.doi: 10.3969/j.issn.1673-8225.2012.18.027

• 器官移植学术探讨 academic discussion of organ transplantation • 上一篇    下一篇

环孢素A在肾移植中的应用：基于Scopus数据库的文献分析

彭  玲   

  1. 郑州大学第二附属医院药剂科，河南省郑州市  450014
  • 收稿日期:2012-01-27 修回日期:2012-03-20 出版日期:2012-04-29 发布日期:2012-04-29
  • 作者简介:彭玲，女，1973年生，河南省息县人，汉族，2002年郑州大学毕业，主管药师，主要从事医院药学方面的研究。p5300230@yahoo.com.cn

The application of cyclosporin A for renal transplantation: The analysis of literature based on Scopus database  

Peng Ling   

  1. Department of Pharmacy, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou450014, China
  • Received:2012-01-27 Revised:2012-03-20 Online:2012-04-29 Published:2012-04-29
  • About author:Peng Ling, Pharmacist in charge, Department of Pharmacy, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, Henan Provine China p5300230@yahoo.com.cn

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摘要：

背景：环孢素A作为免疫抑制剂，已被广泛应用于肾移植后患者，并大大提高了肾移植的存活率。
目的：利用Scopus数据库文献检索和深度分析功能，对于环孢素A在肾移植应用中的文献资料趋势进行多层次探讨分析。
设计：文献计量学分析。
资料提取：以“kidney(肾)，transplant/ transplantation(移植)，immunosuppressive agents/ immunosuppression (免疫抑制剂)，cyclosporin A/CsA(环孢素A)”为关键词，检索Scopus数据库2001-01/2010-12的相关文献，并将分析结果及资料导出，以文字和图表的形式进行统计和计量分析，描述其分布特征。
入选标准：纳入标准：检索与环孢素A在肾移植应用中的相关文献。文献类型包括：①研究原著。②综述。③会议记录。④快报。⑤调查。⑥编辑素材。⑦信件。排除标准：①与文章目的无关的文献。②大于10年较陈旧的文献。③未发表的文章。④重复研究的文献。
主要数据判定指标：以出版时间、国家地区分布、机构分布、文献的类型、来源期刊、学科类别、发表文献的作者分布、文献被引情况进行相关分析。
结果：Scopus数据库2001/2010收录的文献中共检索到4 425篇环孢素A在肾移植应用中的相关文献，研究原著以2 824篇位居首位，其中有7篇可以确定为经典文献，文献数量在时间分布上2001/2005呈上升趋势，2006/2010呈下降趋势，Transplantation Proceedings《移植学会会报》杂志发表文献量最多，929篇，占全部文献的20.99%。
结论：通过文献计量学方法对来源于Scopus数据库关于环孢素A在肾移植应用中的文献进行分析，可为了解该领域的现状、趋势和研究者进一步确定热点难点提供有价值的参考。
 

关键词: 环孢素A, 肾, 移植, 免疫抑制剂, 文献计量, SCI

Abstract:

BACKGROUND: Cyclosporine A as immunosuppressive agents has been widely used in kidney transplant patients, and greatly increased the survival rate of kidney transplantation.
OBJECTIVE: To multivariately analyze the literature on the application of cyclosporin A for renal transplantation through Scopus database and its analysis tool.
DESIGN: Bibliometric analysis.
DATA RETRIEVAL: A retrieval was performed for the literature of the application of cyclosporin A for renal transplantation, including kidney, transplant/transplantation, immunosuppressive agents/immunosuppression, cyclosporin A/CsA during 2001-01 and 2010-12 in Scopus database. The retrieval results were analyzed, and the trends were described in words and graphics.
SELECTIVE CRITERIA: Articles on the application of cyclosporin A for renal transplantation including the following types: (1)Peer-reviewed original paper; (2)Reviews; (3)Conference Papers; (4)Letters; (5)Short Survey; (6)Editorial materials; (7)Note. Exclusive criteria were included (1)Articles unrelated to the study of the application of cyclosporin A for renal transplantation. (2)Articles published before 2001. (3)Articles which were not published on journals. (4)Articles which were duplication research.
MAIN OUTCOME MEASUREMENTS: The literatures were analyzed by publication year, national distribution, institutional information, journal distribution, discipline distribution, authors and citation frequency.
RESULTS: A total of 4 425 literatures on the application of cyclosporin A for renal transplantation were retrieved in Scopus database, in which most of paper were published as original articles. Seven articles were identified as classic literature. The overall number of literature had an upward trend from 2001 to 2005, and a downward trend from 2006 to 2010. Transplantation Proceedings published most papers in this field (n=929, 20.99%).
CONCLUSION: This paper provides a valuable reference for researchers to understand the overview and present situation of this field in order to set further research.

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