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文题释义：
细胞自噬：自噬是真核细胞中在进化上高度保守的分解代谢现象，用于降解回收细胞内生物大分子和细胞器，如错误折叠的蛋白质、衰老或受损的线粒体等，维持细胞的稳态和存活，被认为是Ⅱ型程序性细胞死亡。自噬可分为3种：大自噬、小自噬以及分子伴侣介导的自噬。
力学因素：力学因素是一种重要的应激刺激，细胞为了维持正常的增殖、分化以及其他生理功能，必须适应不断变化的力学环境，一旦出现适应不良的情况，就会表现出一些病理现象，许多疾病的发生就与其组织细胞对力学因素变化适应不良密切相关。异常的力学因素会导致组织细胞出现适应不良的病理现象，自噬也跟这些病理现象密切相关，在许多病变的组织细胞中都发现了自噬的异常表达，如肥大或者衰竭的心脏、出现退行性病变的关节软骨和椎间盘等。
.jpg)
文题释义：
细胞自噬：自噬是真核细胞中在进化上高度保守的分解代谢现象，用于降解回收细胞内生物大分子和细胞器，如错误折叠的蛋白质、衰老或受损的线粒体等，维持细胞的稳态和存活，被认为是Ⅱ型程序性细胞死亡。自噬可分为3种：大自噬、小自噬以及分子伴侣介导的自噬。
力学因素：力学因素是一种重要的应激刺激，细胞为了维持正常的增殖、分化以及其他生理功能，必须适应不断变化的力学环境，一旦出现适应不良的情况，就会表现出一些病理现象，许多疾病的发生就与其组织细胞对力学因素变化适应不良密切相关。异常的力学因素会导致组织细胞出现适应不良的病理现象，自噬也跟这些病理现象密切相关，在许多病变的组织细胞中都发现了自噬的异常表达，如肥大或者衰竭的心脏、出现退行性病变的关节软骨和椎间盘等。