中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (19): 3560-3567.doi: 10.3969/j.issn.1673-8225.2012.19.029

• 干细胞学术探讨 stem cell academic discussion • 上一篇    下一篇

干细胞移植治疗脑卒中的研究与应用

高素娟，熊  杰   

  1. 武警后勤学院附属医院，天津市  300162
  • 收稿日期:2012-01-25 修回日期:2012-03-01 出版日期:2012-05-06 发布日期:2012-05-06
  • 通讯作者: 熊杰，博士，主任医师，武警后勤学院附属医院，天津市 300162
  • 作者简介:高素娟，女，1975年生，河北省行唐县人，汉族，1996年武警医学院毕业，主要从事偏瘫康复研究。907316114@qq.com

Stem cells in the treatment of stroke 

Gao Su-juan, Xiong Jie   

  1. Affiliated Hospital of Armed Police Logistics College, Tianjin  300162, China
  • Received:2012-01-25 Revised:2012-03-01 Online:2012-05-06 Published:2012-05-06
  • Contact: Xiong Jie, Doctor, Chief physician, Affiliated Hospital of Armed Police Logistics College, Tianjin 300162, China
  • About author:Gao Su-juan, Affiliated Hospital of Armed Police Logistics College, Tianjin 300162, China 907316114@qq.com

PDF

388

摘要：

背景：目前脑卒中尚无有效的根治方法。随着人们对神经系统再生与干细胞的认识逐渐加深, 干细胞移植有望成为治疗脑卒中的新手段。 
目的：利用Scopus数据库文献检索和深度分析功能，对干细胞移植治疗脑卒中研究的近6年文献资料进行多角度的探讨分析。
设计：文献计量学分析。
资料提取：由第一作者以“neural stem cells (干细胞)，stroke (脑卒中)，cell transplantation (细胞移植)”为关键词检索Scopus数据库2006-01/2011-12的相关文献，并将分析结果及资料导出，以文字和图表的形式进行统计和计量分析，描述其分布特征。
入选标准：纳入标准：检索干细胞移植治疗脑卒中研究相关的文献。文献类型包括研究原著、综述、会议记录及摘要、快报文章、编辑素材。排除标准：与文章目的无关的文献，大于6年较陈旧的文献，未发表的文章。
主要数据判定指标：发表文献的国家地区分布、作者分布、机构分布、来源期刊、文献被引情况。
结果：Scopus数据库2006/2011收录的文献中共检索到1 045篇干细胞移植治疗脑卒中研究相关的文献，研究原著以517篇位居首位，其中有15篇可以确定为经典文献。在时间分布上，文献数量2006/2011总体呈上升趋势，来源出版物呈分散情况。目前已发表文献中以美国为主，占全球相关领域发稿量的39.8%。中国在过去6年间在数据库中收录文章总量中排在第2名，共发表88篇相关文章，占全球相关文章的8.4%。 
结论：通过文献计量学方法对来源于Scopus数据库关于干细胞移植治疗脑卒中的研究文献进行分析，可为了解该领域的概貌、现状和研究者进一步确定该领域研究的热点难点提供有价值的参考。
关键词：干细胞；脑卒中；脑梗死；细胞移植；文献计量学
doi:10.3969/j.issn.1673-8225.2012.19.029

关键词: 干细胞, 脑卒中, 脑梗死, 细胞移植, 文献计量学

Abstract:

BACKGROUND: Currently, there is lack of effective treating method for stroke. Stem cell transplantation provides a new approach for the treatment of stroke.
OBJECTIVE: To multivariately analyze the literature on stem cells transplantation for the treatment of stroke through Scopus database.
DESIGN: Bibliometric analysis.
DATA RETRIEVAL: A retrieval was performed for the literature of stem cells transplantation for treating stroke during 2006-01 and 2011-12 in Scopus. The retrieval results were analyzed, and the trends were described.
SELECTIVE CRITERIA: Articles on stem cells transplantation for the treatment of stroke include the following types: (1)Peer-reviewed original paper; (2) reviews; (3) meeting notes and abstracts; (4) proceeding papers; (5) editorial materials; (6) letters. Exclusive criteria: (1)Articles unrelated the study of stem cells transplantation for the treatment of stroke. (2)Articles published before 2006.
MAIN OUTCOME MEASUREMENTS: Country distribution, author distribution, institutional information, journal distribution, as well as citation frequency.
RESULTS: A total of 1 045 literatures on stem cells transplantation for the treatment of stroke were retrieved in Scopus database, in which most of paper were published as original articles (n=517). Fifteen articles were identified as classic literatures. The overall number of literature had an upward trend from 2006 to 2011. Currently, United States published most literatures, accounting for 39.8% of all the literatures. Followed by China, which published 88 literatures and accounting for 8.4% of all the published literatures. 
CONCLUSION: This paper provides a valuable reference for researchers to understand the overview and present situation of this field. 

中图分类号: