中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (47): 8919-8922.doi: 10.3969/j.issn.1673-8225.2011.47.045

• 生物材料临床实践 clinical practice of biomaterials • 上一篇    下一篇

脱细胞真皮基质补片治疗小儿肛瘘

王丽亚，董彦清，张鹏举，宫颖新，刘  锋，牛会忠，刘春义   

  1. 河北省儿童医院普外科，河北省石家庄市  050000
  • 收稿日期:2011-05-19 修回日期:2011-06-22 出版日期:2011-11-19 发布日期:2011-11-19
  • 通讯作者: 董彦清，主治医师，河北省儿童医院普外科，河北省石家庄市 050000
  • 作者简介:王丽亚★，女，1957年生，河北省石家庄市人，汉族，硕士生导师,硕士，主任医师，主要从事小儿外科研究。 ddy_rareman@ sohu.com

Acellular dermal matrix patch for treatment of pediatric anal fistula

Wang Li-ya, Dong Yan-qing, Zhang Peng-ju, Gong Ying-xin, Liu Feng, Niu Hui-zhong, Liu Chun-yi   

  1. Department of General Surgery, Hebei Provincial Children Hospital, Shijiazhuang  050000, Hebei Province, China
  • Received:2011-05-19 Revised:2011-06-22 Online:2011-11-19 Published:2011-11-19
  • Contact: Dong Yan-qing, Attending physician, Department of General Surgery, Hebei Provincial Children Hospital, Shijiazhuang 050000, Hebei Province, China
  • About author:Wang Ya-li★, Master, Master’s supervisor, Chief physician, Department of General Surgery, Hebei Provincial Children Hospital, Shijiazhuang 050000, Hebei Province, China ddy_rareman@ sohu.com

PDF

487

被引次数

7

摘要：

背景：采用异体脱细胞真皮基质材料填塞治疗成人低位肛瘘具有较好的临床效果。
目的：探讨脱细胞异体真皮基质补片修补小儿肛瘘的可行性以及方法。
方法：将138例肛瘘患儿随机分为2组，用可吸收线将脱细胞异体真皮基质生物补片固定在直肠黏膜下，A组双层缝合封闭内口，B组不游离、缝合内口。
结果与结论：随访观察6个月，所有病例肛周无红肿，外观无异常，外口硬结消失，内口愈合良好，无肛门狭窄及肛门外形改变。两组在修复后均有部分患儿出现瘘口出流便，但未经特殊处理，症状均自行消失，痊愈。A组术后瘘口漏便患儿人数较B组多(P < 0.01)，出现时间较B组早(P < 0.05)，但总体愈合时间无差异。说明手术中仅固定补片于内口，而不游离、缝合内口即可达到满意疗效。

关键词: 脱细胞异体真皮基质, 小儿肛瘘, 补片, 修复, 生物材料

Abstract:

BACKGROUND: Allogenous acellular dermal matrix patches have a good clinical effect on adult anal fistula.
OBJECTIVE: To investigate the feasibility and approach of allogenous acellular dermal matrix patches in repair of pediatric anal fistula.
METHODS: Totally 138 cases of pediatric anal fistula were randomized into two groups to receive allogenous acellular dermal matrix patch suture: group A, double-layer suture closure; group B, non-free suture.
RESULTS AND CONCLUSION: All the cases were followed for 6 months. There were no perianal swelling, abnormal appearance, induration, anal stenosis and anal shape change. After repair, some children presented with reuben from the fistula that was healed without treatment. The number of children with reuben from the fistula in group A was higher than that of group B (P < 0.01), and the appearance time was also earlier in group A (P < 0.05). Allogenous acellular dermal matrix patch has a good effect on pediatric anal fistula.

中图分类号: