中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (51): 9671-9674.doi: 10.3969/j.issn.1673-8225.2010.51.040

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

肩关节骨损伤与人工材料修复　

冯  艳   

  1. 郑州大学体育系，河南省郑州市     450001
  • 出版日期:2010-12-17 发布日期:2010-12-17
  • 作者简介:冯艳★，女，1979年生，河南省濮阳市人，汉族，2007年北京体育大学毕业，硕士，讲师，主要从事运动训练与体育康复保健学研究。 sqh@hpu.edu.cn

Shoulder joint bone injury repaired with artificial materials

Feng Yan   

  1. Department of Physical Education, Zhengzhou University, Zhengzhou   450001, Henan Province, China
  • Online:2010-12-17 Published:2010-12-17
  • About author:Feng Yan★, Master, Lecturer, Department of Physical Education, Zhengzhou University, Zhengzhou 450001, Henan Province, China sqh@hpu.edu.cn

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摘要：

目的：对肩关节骨损伤生物力学特点进行探讨，并对肩关节骨损伤后人工生物材料干预下的治疗手段与机制进行分类与归纳。
方法：作者应用计算机检索PubMed数据库(http://www.ncbi.nlm.nih.gov/PubMed)及CNKI数据库(www.cnki.net/index.htm)，在标题和摘要中以“肩关节，骨折，生物材料，治疗”或“shoulder joint, fracture, biological materials, treatment”为检索词进行检索。选择与肩关节生物力学特点、肩关节损伤及人工生物材料治疗相关的文献，同一领域文献则选择近期发表或发表在权威杂志文章。
结果：共纳入24篇文献进一步归纳分析。肩关节是人体活动范围最大也是最为灵活的关节，体操运动在上肢支撑过程中，由于受力的突发性或暴力作用下，肩关节骨损伤较为常见。目前严重的肩关节损伤修复技术大多以肩关节假体置换为主，随着现代医学水平的进步与发展，人工生物工程逐步运用于运动医学领域，人工生物材料在骨损伤治疗过程中的运用也逐步成熟与多样化，但在肩关节骨折修复措施中较为鲜见。
结论：肩关节假体设计过程中，其目的都是为了尽可能低恢复肩关节损伤前的生理结构和功能作用。所以，假体设计所需的基本参数都应通过解剖学手段的不断深入研究来获得，同时假体的发展也可推动形态学的研究和进步，为骨形态学和表面修饰的发展和深入研究起到了相应的推进作用。另外，目前研究人员在骨修复材料的选择、处理以及材料表面修饰等多方面的尝试已取得了较好的效果。随着细胞生物学和分子生物学方法和技术的进步，以及基因疗法等方法的运用，肩关节骨损伤修复的研究必将进入崭新阶段，也为肩关节骨折修复人工材料的妥善运用提供了更为崭新的研究方向。

关键词: 人工材料, 肩关节, 力学特点, 骨损伤, 治疗

Abstract:

OBJECTIVE: To investigate the biomechanical characteristics of shoulder joint bone injury, to classify and summarize the treatment approach and mechanism underlying artificial biomate4rial intervention after shoulder joint bone injury.
METHODS: A computer-based online search of PubMed database (http://www.ncbi.nlm.nih.gov/PubMed) and CNKI database (www.cnki.net / index.htm) was performed using key words of “shoulder joint, fracture, biological materials, treatment” to search the title and abstracts. Studies related to the biomechanical characteristics of should joint, shoulder joint injury and treatment of artificial biomaterials were included, and those recently published or published in the authority journals were preferred in the same field.
RESULTS: A total of 24 studies were involved in analysis. Shoulder joint is the most flexible joint with the largest movement range, Shoulder joint bone injury is common in gymnastics due to sudden force or violence in the process of upper extremity supporting. Present repair technology for serious shoulder injury is mostly shoulder prosthesis, with the advanced modern medicine, artificial biological engineering has been gradually applied to the field of sports medicine, artificial biomaterials are becoming mature and diversified in bone injury treatment, but rarely reported in the shoulder joint fracture repair.
CONCLUSION: In the shoulder joint prosthesis design process, the goal is to restore the physiological structure and function of shoulder joint before injury. Therefore, the basic parameters that prosthesis design requires should be obtained by means of continuous in-depth study of anatomy, while the development of prosthesis can also promote morphology research and progress, plays a promoting role in development and in-depth study of bone morphology and surface modification. In addition, researchers have achieved good results in bone repair material selection, processing and surface modification. With the cell biology and molecular biology methods and technology advance, as well as the use of gene therapy, researches on shoulder joint bone injury repair will enter a new phase, and offer a new research direction for the proper use of artificial materials for should joint fracture repair.

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