中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (35): 6484-6488.doi: 10.3969/j.issn.2095-4344.2012.35.005

• 数字化骨科 digital orthopedics • 上一篇    下一篇

戴用口腔矫治器后阻塞性睡眠呼吸暂停低通气综合征患者舌骨力学的有限元分析

姜 伟,曲爱丽,王春秀,刘 旦,宿友亮   

  1. 宁夏大学机械工程学院,宁夏回族自治区银川市 750021
  • 收稿日期:2011-12-04 修回日期:2012-02-24 出版日期:2012-08-26 发布日期:2012-08-26
  • 通讯作者: 王春秀,硕士,教授,宁夏大学机械工程学院,宁夏回族自治区银川市750021 1024557979@qq.com
  • 作者简介:姜伟★,男,1983年生,内蒙古自治区阿拉善左旗人,汉族,宁夏大学机械工程学院在读硕士,主要从事机械制造及自动化专业方面的研究。 359025744@qq.com

Finite element analysis on hyoid bone mechanics in obstructive sleep apnea hypopnea syndrome patient inserted with oral appliance

Jiang Wei, Qu Ai-li, Wang Chun-xiu, Liu Dan, Su You-liang   

  1. School of Mechanical Engineering of Ningxia University, Yinchuan 750021, Ningxia Hui Autonomous Region, China
  • Received:2011-12-04 Revised:2012-02-24 Online:2012-08-26 Published:2012-08-26
  • Contact: Wang Chun-xiu, Master, Professor, School of Mechanical Engineering of Ningxia University, Yinchuan 750021, Ningxia Hui Autonomous Region, China 1024557979@qq.com
  • About author:Jiang Wei★, Studying for master’s degree, School of Mechanical Engineering of Ningxia University, Yinchuan 750021, Ningxia Hui Autonomous Region, China 359025744@qq.com

摘要:

背景:采用三维有限元对下颌骨、气道、舌骨等共同建模进行研究的报道较少。
目的:通过建立下颌骨、气道、舌骨以及周围肌肉组织的模型,模拟戴用矫治器使下颌前伸改变气道形态的状况,在下颌骨上进行前伸加载,分析舌骨的生物力学表现。
方法:选取1名确诊为阻塞性睡眠呼吸暂停低通气综合征的男性患者,螺旋CT扫描眼眶下缘至甲状软骨图像,导入Mimics10.01软件分别提取各组织,Imageware10再对得到的文件点云进行处理,由ANSYS 10.0等软件生成三维有限元模型。在下颌骨上分别加载2,4,6,8 mm的前伸量,观察舌骨的生物力学表现。
结果与结论:上气道的应力主要集中在软腭及口咽部,舌骨上的应力主要集中在与下颌、气道相连的肌肉处。随着下颌前伸量加大,应力大小随伸长量增加而增大,舌骨随着肌肉的牵拉主要沿前上方移动。结果说明三维有限元法能够建立具有较高几何相似性及力学相似性的模型,是阻塞性睡眠呼吸暂停低通气综合征病理研究方法的扩充。

关键词: 口腔矫治器, 阻塞性睡眠呼吸暂停低通气综合征, 舌骨, 三维有限元, 下颌前伸

Abstract:

BACKGROUND: The researches on the modeling establishment of mandibular, airway and hyoid bone by three-dimensional finite element are rare.
OBJECTIVE: To establish the model of mandible, airway as well as hyoid bone and surrounding muscular tissues in order to change the upper airway structure by simulating the situation of oral appliance inserted in obstructive sleep apnea hypopnea syndrome patient. And to study the biomechanical performance of hyoid bone by load forward displacement on mandibular.
METHODS: One male obstructive sleep apnea hypopnea syndrome patient was chosen. Spiral CT scanning technology was used to obtain CT images from the lower edge of the orbit to the thyroid cartilage. The different organizations were segmented out in Mimics10.01 software. Then the point cloud from Mimics10.01 software was processed in Imageware10 software. Finally, a three-dimensional finite element model was constructed in ANSYS10.0 software. Then, 2, 4, 6 and 8 mm forward displacements of mandibula were placed. The biomechanical performance of hyoid bone was observed.
RESULTS AND CONCLUSION: The results show that the stress on the upper airway was mainly concentrated in the soft palate and oropharynx. The stress on the hyoid bone was focused on muscles which connect the lower jaw and airway. As the size of the mandibular advanced continuously the stress was increased. The hyoid bone mainly moved along forward and upward as the muscles pulled it. The way of three-dimensional finite element analysis can build a model with a high geometrical and mechanical similarity. It extends the methods to research obstructive sleep apnea hypopnea syndrome pathology.

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