中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (28): 5175-5180.doi: 10.3969/j.issn.2095-4344.2012.28.010

• 组织构建实验造模 experimental modeling in tissue construction • 上一篇    下一篇

构建卵巢肿瘤数字化盆腔解剖模型及三维可视化技术分析卵巢肿瘤的血供

李湘元1，何援利1，方驰华2，王雪峰1，彭冬先1，朱洪磊1，王显龙3   

  1. 南方医科大学珠江医院，1妇产科，2肝胆一科，3影像诊断科，广东省广州市 510282
  • 收稿日期:2012-04-01 修回日期:2012-06-18 出版日期:2012-07-08 发布日期:2012-07-08
  • 通讯作者: 何援利，硕士，主任医师，教授，博士生导师，南方医科大学珠江医院妇产科，广东省广州市 510280 hyl@gdvnet.com
  • 作者简介:李湘元★，女，1986年生，汉族，湖南省长沙市人，南方医科大学在读硕士，医师，主要从事妇科肿瘤三维可视化研究工作。 dlinkforever@163.com

Construction of a digital pelvic anatomy model and analysis of the blood supply of ovarian tumor by three-dimensional visualization system

Li Xiang-yuan1, He Yuan-li1, Fang Chi-hua2, Wang Xue-feng1, Peng Dong-xian1, Zhu Hong-lei1, Wang Xian-long3   

  1. 1Department of Obstetrics and Gynecology,
    2First Department of Hepatobiliary Surgery,
    3Department of Radiological Imaging, Zhujiang Hospital of Southern Medical University, Guangzhou 510282, Guangdong Province, China
  • Received:2012-04-01 Revised:2012-06-18 Online:2012-07-08 Published:2012-07-08
  • Contact: He Yuan-li, Master, Chief physician, Doctoral supervisor, Department of Obstetrics and Gynecology Zhujiang Hospital of Southern Medical University, Guangzhou 510282, Guangdong Province, China hyl@gdvnet.com
  • About author:Li Xiang-yuan★, Studying for master’s degree, Physician, Department of Obstetrics and Gynecology Zhujiang Hospital of Southern Medical University, Guangzhou 510282, Guangdong Province, China dlinkforever@163.com

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587

被引次数

7

摘要：

背景：卵巢肿瘤的影像学表现具有多样性和可变性，目前各种影像检查方法都不易对卵巢肿瘤做出确切的定性诊断。
目的：利用腹部医学图像三维可视化系统，对不同类型卵巢肿瘤患者的盆腔结构进行三维重建，获得数字化解剖模型，探索其在精确选择手术方式中的临床应用价值。
方法：收集卵巢肿瘤的65例住院患者的盆腔CT数据，根据治疗后病理结果分类，其中良性肿瘤组30例，恶性肿瘤组25例，交界性肿瘤组10例，应用腹部医学图像三维可视化系统对其的64排螺旋CT扫描数据进行三维重建，获得的卵巢肿瘤三维立体图，按照肿瘤内血管的分布、走行、分支情况等特点，将肿瘤内血流分布分为3型：①Ⅰ型为肿瘤周边可见弧形或短条状血管，肿瘤内部未见血管分布。②Ⅱ型除周边血管外，肿瘤内部可见稀疏的血管，血管分支简单，走行较平直。③Ⅲ型为肿瘤内部可见丰富的血管或血管网，血管走行迂曲、不规则且分支复杂，肿瘤周边亦可见血管包绕。
结果与结论：对肿瘤血供与卵巢肿瘤性质之间的关系进行分析，结果显示，各组血管类型分布与卵巢肿瘤性质存在相关性(χ2=43.93，P < 0.01)。良性肿瘤组以Ⅰ型血管为主，恶性肿瘤组以复杂型Ⅱ，Ⅲ型血管为主。交界性肿瘤大多在良性基础上衍变成为“低度恶性倾向”，交界性肿瘤组有8例肿瘤血管类型表现为复杂型Ⅱ，Ⅲ型。结果证实，实验成功构建了卵巢肿瘤患者数字化盆腔解剖模型，良性，恶性和交界性肿瘤血管类型存在差异。

关键词: 卵巢肿瘤, 成像, 三维, 良性肿瘤, 恶性肿瘤, 交界性肿瘤, 数字化图像影像技术

Abstract:

BACKGROUND: Imaging performance of ovarian tumor has diversity and variability. Therefore, accurate qualitative diagnosises cannot be obtained from the current imaging methods.
OBJECTIVE: To perform the three-dimensional reconstruction of the pelvis in patients with different types of ovarian tumor so as to obtain digital anatomical models and then to explore its value in surgical selection using medical image three-dimensional visualization system of the abdomen.
METHODS: Pelvic CT data of 65 hospitalized patients with ovarian tumor were collected and classified into benign tumor group (30 cases), malignant tumor group (25 cases) and borderline tumor group (10 cases) according to pathological results after treatment. The data obtained from 64-slice helical CT angiography were used for the three-dimensional reconstruction using the medical image three-dimensional visualization system to harvest three-dimensional virtual models of ovarian tumor. According to the vascular distribution, walking and branch in tumor, tumor blood flow was divided into type Ⅰ, type II and type Ⅲ. ①The tumor vessels of type Ⅰ were curved or short bar-shaped around the tumors, which could not be seen within the tumors. ②The tumor vessels of type Ⅱ were sparse in tumors besides around the tumors, and vascular branch was simple and straight. ③The tumor vessels of type Ⅲ were abundant or vascular network could be seen within the tumor. Besides, the vessels were tortuous, irregular and showed complex branches, and these also could be found around the tumors.
RESULTS AND CONCLUSION: By analyzing the relationship between tumor blood supply and ovarian tumor properties, we found that there was a correlation between the distribution of vascular type in each group and ovarian tumor properties (x2=43.93, υ=2, P < 0.01). The tumor vessels of typeⅠwere mainly found in the benign tumor group, and the tumor vessels of type Ⅱ or type Ⅲ were almost found in the malignant tumor group. In addition, eight cases in the borderline tumor group showed the tumor vessels of type Ⅱ and type Ⅲ. These results suggest that the digital pelvic anatomy model of patients with ovarian tumor was successfully established, and there were differences in vessel types among benign, malignant and borderline tumors.

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