中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (3): 547-550.doi: 10.3969/j.issn.1673-8225.2012.03.038

• 生物材料临床实践 clinical practice of biomaterials • 上一篇    下一篇

Willis环周围窄颈动脉瘤与栓塞材料选择的相关性*

史  跃1，黄玉杰2，蔡廷江3，王安明1，高从敬1   

  1. 解放军第九七医院，1介入放射科，3神经外科，江苏省徐州市　221004 ；2南京大学医学院附属鼓楼医院神经外科，江苏省南京市　210008
  • 收稿日期:2011-06-30 修回日期:2011-07-30 出版日期:2012-01-15 发布日期:2012-01-15
  • 通讯作者: 黄玉杰，主任医师，南京大学医学院附属鼓楼医院神经外科，江苏省南京市　210008 huangyujie2000@163.com
  • 作者简介:史跃，男，1966年生，江苏省徐州市人，1989年第一军医大学毕业，副主任医师，主要从事微创介入治疗的研究。 shiyue66@ 126.com
  • 基金资助:

    军队“十一五”医学科学研究计划课题(项目编号2006-MA46)，课题名称：DSA对缺血性脑血管疾病的早期诊断及介入治疗应用研究

Correlation between narrow carotid artery aneurysm around Willis ring and selection of embolic materials

Shi Yue1, Huang Yu-jie2, Cai Ting-jiang3, Wang An-ming1, Gao Cong-jing1   

  1. 1Department of Interventional Radiology, the 97th Hospital of Chinese PLA, Xuzhou  221004, Jiangsu Province, China; 2Department of  Neurosurgery, Drum Tower Hospital, Medical School of Nanjing University, Nanjing  210008, Jiangsu Province, China; 3Department of Neurosurgery, the 97th Hospital of Chinese PLA, Xuzhou  221004, Jiangsu Province, China
  • Received:2011-06-30 Revised:2011-07-30 Online:2012-01-15 Published:2012-01-15
  • Contact: Huang Yu-jie, Chief physician, Department of Neurosurgery, Drum Tower Hospital, Medical School of Nanjing University, Nanjing 210008, Jiangsu Province, China huangyujie2000@ 163.com
  • About author:Shi Yue, Associate chief physician, Department of Interventional Radiology, the 97th Hospital of Chinese PLA, Xuzhou 221004, Jiangsu Province, China shiyue66@126.com
  • Supported by:

    the Medical Science Research Plan during the Military Eleventh Five-year Plan Period, No. 2006-MA46*

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摘要：

背景：随着影像学设备与栓塞材料的不断发展，颅内动脉瘤的血管内栓塞治疗也成为治疗方法之一。
目的：探讨Willis环周围窄颈动脉瘤的形态学特点与栓塞材料选择及血管内栓塞治疗的关系。
方法：用双源CT血管成像检查筛选患者，采用Seldinger技术行全脑血管造影，根据动脉瘤的不同解剖学形态选用合适的弹簧圈进行介入栓塞治疗。
结果与结论：31例患者共36枚动脉瘤均成功栓塞，完全栓塞31枚、占86.11%，大部分栓塞5枚、占13.89%；随访6~12个月，所有患者均未发生再出血或脑血栓形成；动脉瘤的栓塞程度不仅与动脉瘤的形态有关，而且与栓塞材料直接相关。故认为根据不同的形态学特点选用合适的弹簧圈进行血管内栓塞治疗，是一种安全有效的方法。

关键词: 弹簧圈, Willis环, 窄颈动脉瘤, 介入治疗, 脑血栓

Abstract:

BACKGROUND: With the continuous development of the imaging equipments and embolic materials, intracranial aneurysm endovascular embolization has become a treatment method.
OBJECTIVE: To investigate the relationship of the morphological features of narrow carotid artery aneurysm around the Willis ring with the embolic material selection and endovascular embolization treatment.
METHODS: Dual-source CT angiography screening examination was performed in patients undergoing Seldinger technique of cerebral angiography with digital signature algorithm, according to the different anatomical forms of aneurysm, the appropriate choice of coil was conducted for embolization.
RESULTS AND CONCLUSION: Thirty-one patients with 36 aneurysms were successfully embolized, complete thrombosis in 31, accounting for 86.11%, the majority of embolization in 5, accounting for 13.89%. After a follow-up of 6 to 12 months, all patients did not present with re-bleeding or thrombosis. Aneurysm embolization was not only related to the aneurysm shape, but also related to embolic materials. Therefore, to choose appropriate endovascular coil according to the morphological characteristics is a safe and effective method.

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