中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (49): 9303-9306.doi: 10.3969/j.issn.1673-8225.2011.49.043

• 干细胞学术探讨 stem cell academic discussion • 上一篇    下一篇

胚胎干细胞研究的伦理和心理学问题

董效信1，任晓敏2，董雅妮3   

  1. 1解放军济南军区青岛第二疗养院心理科，山东省青岛市  266071
    2中国石油化工股份有限公司青岛安全工程研究院健康监护中心，山东省青岛市  266071
    3美国哥伦比亚大学
  • 收稿日期:2011-10-29 修回日期:2011-11-12 出版日期:2011-12-03 发布日期:2011-12-03
  • 作者简介:董效信，男，1959年生，主任医师，主要从事医学心理学的研究。 Qddxx2002@yahoo.com.cn

Ethical and psychologial issues of embryonic stem cell researches

Dong Xiao-xin1, Ren Xiao-min2, Dong Ya-ni3   

  1. 1Department of Psychology, Jinan Second Qingdao Sanatorium, Jinan Military Area Command of Chinese PLA, Qingdao  266071, Shandong Province, China
    2Health Care Center, Qingdao Safety Engineering Institute, China Petrochemical Corporation or Sinopec Group, Qingdao  266071, Shandong Province, China
    3Columbia University, New York, NY 10027, USA
  • Received:2011-10-29 Revised:2011-11-12 Online:2011-12-03 Published:2011-12-03
  • About author:Dong Xiao-xin, Chief physician, Department of Psychology, Jinan Second Qingdao Sanatorium, Jinan Military Area Command of Chinese PLA, Qingdao 266071, Shandong Province, China Qddxx2002@yahoo.com.cn

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摘要：

背景：胚胎干细胞研究具有重要的医学价值，在基因治疗、组织工程学、药学等许多领域都具有广泛的应用，使人们看到了治疗疾病的新希望，而其相关研究成果也引发了许多伦理和心理学问题。
目的：综述目前胚胎干细胞研究中的伦理和心理学问题。
方法：应用计算机检索2001-01/2010-12 PubMed数据库、维普数据库及万方数据库有关干细胞研究产生的伦理和心理学问题相关文献，英文检索词“embryonic stem cells，morality，psychological”，中文检索词“胚胎干细胞，伦理学，心理学”。检索文献量总计122篇，最终纳入符合标准的文献33篇。
结果与结论：胚胎干细胞究中伦理学问题的焦点主要包括：干细胞来源的伦理学问题，干细胞“克隆”的伦理学问题，干细胞与生命的伦理学问题，干细胞研究存在和需要解决的问题及干细胞研究中伦理学规范问题。干细胞研究中的心理学问题主要是人们对干细胞研究特别是“克隆”技术的认识。相关研究多涉及造血干细胞移植患者的心理变化。胚胎干细胞的研究目前已取得了突破性成果，给医疗、卫生健康等方面带来了革命性影响。

关键词: 伦理学, 心理学, 胚胎, 干细胞, 综述文献

Abstract:

BACKGROUND: Embryonic stem cell research has important medical value and is widely used in fields of gene therapy, tissue engineering and pharmacy, these research achievements can provide a new hope for treatment of diseases, however, causes many ethical and psychological issues.
OBJECTIVE: To summarize the ethical and psychological issues in current studies regarding the embryonic stem cells.
METHODS: A computer-based retrieval was performed in PubMed database, VIP database and Wanfang database from January 2001 to December 2010, for documents regarding the ethical and psychological issues in stem cell researches. The key words were "embryonic stem cells, morality, psychological" in English, and "embryonic stem cells, ethics, psychology" in Chinese. Totally 122 papers were screened out and 33 of them were ultimately included in the analysis.
RESULTS AND CONCLUSION: The ethical issues of embryonic stem cell researches include the source of stem cells, stem cell cloning, stem cells and life, the existing problems of stem cell research and the related ethical specifications. The psychological issues of stem cell research mainly focus on the understanding of stem cell research, especially cloning technology. A number of researches are involved in the psychological changes of patients after hematopoietic stem cells transplantation. We have made a breakthrough in field of embryonic stem cell research, thus bring a revolutionary impact on the medical and health issues.

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