中国组织工程研究 ›› 2022, Vol. 26 ›› Issue (33): 5283-5289.doi: 10.12307/2022.748

• 数字化骨科 digital orthopedics • 上一篇    下一篇

3D-CT指导单侧双通道内镜下定位L5、S1神经根及椎间隙

毕经纬,任佳彬,刘  鑫,孙  宁,李  瑞,李岳飞,孙兆忠   

  1. 滨州医学院附属医院脊柱外科,山东省滨州市   256603
  • 收稿日期:2021-11-11 接受日期:2021-12-24 出版日期:2022-11-28 发布日期:2022-03-30
  • 通讯作者: 孙兆忠,主任医师,滨州医学院附属医院脊柱外科,山东省滨州市 256603
  • 作者简介:毕经纬,男,1995年生,山东省济南市人,汉族,滨州医学院在读硕士,主要从事微创脊柱外科方面的研究。
  • 基金资助:
    国家重点研发计划资助项目(2017YFC0114002),子项目负责人:孙兆忠;山东省自然科学基金资助项目(ZR2017LH021),项目负责人:孙兆忠

3D-CT-guided unilateral biportal endoscopic localization of L5 and S1 nerve roots and intervertebral space

Bi Jingwei, Ren Jiabin, Liu Xin, Sun Ning, Li Rui, Li Yuefei, Sun Zhaozhong   

  1. Department of Spine Surgery, Affiliated Hospital of Binzhou Medical College, Binzhou 256603, Shandong Province, China
  • Received:2021-11-11 Accepted:2021-12-24 Online:2022-11-28 Published:2022-03-30
  • Contact: Sun Zhaozhong, Chief physician, Department of Spine Surgery, Affiliated Hospital of Binzhou Medical College, Binzhou 256603, Shandong Province, China
  • About author:Bi Jingwei, Master candidate, Department of Spine Surgery, Affiliated Hospital of Binzhou Medical College, Binzhou 256603, Shandong Province, China
  • Supported by:
    the Nation Key Research and Development Program, No. 2017yfc0114002 (to SZZ); the Natural Science Foundation of Shandong Province, No. zr2017lh021(to SZZ)

摘要:

文题释义:
单侧双通道内镜技术:是目前治疗腰椎管狭窄症的内镜技术之一,采用双通道分离式操作,镜头和器械互不干扰,自由活动度大,应用传统器械操作,该技术治疗腰椎管狭窄症有独特优势。
3D-CT测量:将患者腰椎CT原始数据导入MIMICS软件行数字化三维重建,在此基础上观测相关解剖学指标。

背景:单侧双通道内镜视角下能更直接、清晰地近距离辨识镜下组织结构特点,而间接的X射线透视等难以定位硬脊膜、神经根及椎间盘。
目的:探讨单侧双通道内镜下L5、S1神经根及椎间隙的毗邻关系,为单侧双通道内镜技术治疗腰椎管狭窄症提供理论依据。
方法:纳入符合标准的29例腰椎管狭窄症患者,行腰椎CT脊髓造影检查,图像导入Mimics 17.0软件建立三维模型,测量L4/5和L5S1节段相关参数:上位腰椎椎板下缘与下关节突基底部内侧缘交点(A点)分别至硬脊膜外侧缘(a1)、神经根起点上缘(a2)、上位腰椎下终板(a3)、下位腰(或骶)椎上终板的距离(a4);下位腰(或骶)椎椎板上缘与上关节突基底部内侧缘交点(B点)分别至硬脊膜外侧缘(b1)、神经根起点上缘(b2)、上位腰椎下终板(b3)、下位腰(或骶)椎上终板的距离(b4);上位腰椎下关节突内侧缘与下位腰(或骶)椎上关节突内侧缘交点(C点)分别至硬脊膜外侧缘(c1)、神经根起点上缘(c2)、上位腰椎下终板(c3)、下位腰(或骶)椎上终板的距离(c4);上位腰椎棘突侧方与椎板下缘交点(D点)至硬脊膜外侧缘的距离(d1);神经根起点上缘分别至上位腰椎下终板(n1)、下位腰(或骶)椎上终板的距离(n2)。观察A、B、C三点围成的三角形区域(C区)与神经根、椎间隙的位置关系。29例患者均行单侧双通道内镜下腰椎管减压术,采用疼痛目测类比评分、Oswestry功能障碍指数、日本骨科协会评分评估疗效。分析参数并临床验证其可靠性。
结果与结论:①同节段患侧与健侧各结构位置关系差异无显著性意义(P > 0.05),L4/5和L5S1不同节段A、B、C各点与硬脊膜外侧缘、椎间隙距离差异有显著性意义(P < 0.05)、与神经根起点上缘距离差异无显著性意义(P>0.05),L5、S1神经根起点上缘与相应节段椎间隙距离差异有显著性意义(P < 0.05);②L4/5、L5S1节段,A点投影绝大多数分别在L5上、下终板附近;AB连线投影均分别在硬脊膜外侧缘附近、硬脊膜外侧缘以外;③椎间隙水平在L4/5节段绝大多数在C区以上,A点之上;L5S1节段均在C区内,A点之下,C点水平绝大多数对应椎间隙;④神经根起点上缘L5绝大多数投影在L4/5椎间隙水平,S1均投影在L5S1椎间隙以上;⑤观测结果与术中所见相符合;⑥提示获取数据可指导单侧双通道内镜术中定位,单侧双通道内镜镜下显露恒定的各骨性标志点,在L4/5节段,A点以上即为椎间隙,探查并取出突出的椎间盘,在椎间隙水平找到L5神经根起点,沿神经走行对神经根管减压;在L5S1节段,C点位于椎间隙水平,自该水平探查椎间盘,自A点稍上开窗找到S1神经根起点并向外下对神经减压;通过各标志点定位椎间隙、神经根位置,并明确开窗减压范围,使修复过程更安全、精准、有效、高效。
缩略语:退行性腰椎管狭窄症:lumbar spinal stenosis,LSS;单侧双通道内镜:unilateral biportal endoscopic,UBE

https://orcid.org/0000-0002-2696-0419 (毕经纬)

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱;骨折;内固定;数字化骨科;组织工程

关键词: 腰椎, 椎管狭窄, 单侧双通道内镜, 数字化骨科, 三维重建, 形态学参数

Abstract: BACKGROUND: Unilateral biportal endoscopy can more directly and clearly identify tissue structure characteristics at close range, while indirect X-ray fluoroscopy is difficult to locate the dura mater, nerve roots and intervertebral disc.
OBJECTIVE: To investigate the relationship between L5 and S1 nerve roots and intervertebral space under unilateral biportal endoscopy, and to provide theoretical basis for the treatment of lumbar spinal stenosis with unilateral biportal endoscopy.
METHODS: Totally 29 patients with lumbar spinal stenosis underwent lumbar CT myelography. The images were imported into Mimics 17.0 software to establish a three-dimensional model. The relevant parameters of L4/5 and L5S1 levels were measured: The distance from the intersection of the lower edge of upper lumbar lamina and the medial edge of the base of the lower articular process (point A) to the lateral edge of the dural membrane (a1), the upper edge of the starting nerve root (a2), the lower endplate of upper lumbar spine (a3), and the upper endplate of lower lumbar (or sacral) vertebrae (a4); the distance from the intersection of the upper edge of the lower lumbar (or sacral) vertebral lamina and the medial edge of the base of the superior articular process (point B) to the lateral edge of the dural membrane (b1), the upper edge of the nerve root origin (b2), the lower endplate of the upper lumbar spine (b3), and the upper endplate of the lower lumbar (or sacral) vertebral body (b4); the distance from the intersection point of the medial edge of the inferior articular process of the upper lumbar spine to the medial edge of the inferior lumbar (or sacral) superior articular process (point C) to the lateral edge of the dural membrane (c1), the upper edge of the nerve root origin (c2), the lower endplate of the upper lumbar spine (c3), and the upper endplate of the lower lumbar (or sacral) vertebral body (c4); the distance from the intersection of the upper lumbar spinous process and the lower edge of the lamina (point D) to the lateral edge of the dural membrane (d1); the distance from the upper edge of the nerve root to the upper endplate of the lumbar spine (n1) and the upper endplate of the lumbar spine (or sacral) (n2). The position relationship between the triangle area (C area) surrounded by A, B and C and nerve roots and intervertebral space was observed. All 29 patients underwent unilateral biportal endoscopic lumbar decompression, and were evaluated by visual analogue pain score, Oswestry disability index, and Japanese Orthopaedic Association evaluation score. The parameters were analyzed and their reliability was verified clinically. 
RESULTS AND CONCLUSION: (1) There was no significant difference in the relationship between the affected side and the healthy side in the same segment (P > 0.05). There were significant differences between A, B and C of L4/5 and L5S1 and the distance between the lateral dural edge and intervertebral space (P < 0.05) and had no significant difference with the distance from the upper edge of nerve root origin (P > 0.05). The distance between the upper edge of L5 and S1 nerve root and the intervertebral space of the corresponding segment was significantly different (P < 0.05). (2) In L4/5 and L5S1 segments, the projection of point A was mostly near the upper and lower endplates of L5. AB line projection was located near and outside the lateral edge of the dural membrane. (3) The level of intervertebral space in L4/5 segment was mostly above C area, above point A; L5S1 segments were all in region C, below point A, and most of them corresponded to the intervertebral space at the level of point C. (4) Most of L5 at the upper edge of nerve root origin was projected at the level of L4/5 intervertebral space, while S1 was projected above L5S1 intervertebral space. (5) The observed results were consistent with the intraoperative findings. (6) The obtained data can guide the positioning of unilateral biportal endoscopy, and the constant bone markers are exposed under unilateral biportal endoscopy microscope. At the L4/5 segment, above point A is the intervertebral space. The herniated disc is explored and removed, and the starting point of L5 nerve root is found at the intervertebral space level, and the nerve root canal is decompressed along the nerve alignment. At L5S1, point C was located at the intervertebral space level, and the disc was explored from this level. A window was opened slightly above point A to find the origin of S1 nerve root and decompress the nerve outward and downward. The location of intervertebral space and nerve root was determined by each marker point, and the scope of decompression was determined to make the operation more safe, accurate, effective, and efficient.

Key words: lumbar spine, spinal stenosis, unilateral biportal endoscopic technique, digital orthopedics, three-dimensional reconstruction, morphological parameter

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