中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (12): 2261-2264.doi: 10.3969/j.issn.1673-8225.2012.12.040

• 生物材料综述 biomaterial review • 上一篇    下一篇

不同材料周围动脉支架置入治疗动脉硬化闭塞症的研究与进展

吴田方，代远斌   

  1. 重庆医科大学附属第一医院血管外科，重庆市  400016
  • 收稿日期:2011-10-25 修回日期:2012-01-05 出版日期:2012-03-18 发布日期:2012-03-18
  • 通讯作者: 代远斌，主任医师，重庆医科大学附属第一医院血管外科，重庆市 400016 dyb630611@ 163.com
  • 作者简介:吴田方，男，1981年生，贵州省独山县人，布依族，2004年河北医科大学毕业，主要从事血管外科的研究。 15823984308@ 139.com

The research progress of different-material peripheral arterial stent placement in treating arteriosclerotic occlusive disease

Wu Tian-fang, Dai Yuan-bin   

  1. Department of Vascular Surgery, First Affiliated Hospital of Chongqing Medical University, Chongqing  400016, China
  • Received:2011-10-25 Revised:2012-01-05 Online:2012-03-18 Published:2012-03-18
  • Contact: author: Dai Yuan-bin, Chief physician, Department of Vascular Surgery, First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China dyb630611@ 163.com
  • About author:Wu Tian-fang, Department of Vascular Surgery, First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China 15823984308@ 139.com

PDF

489

被引次数

6

摘要：

背景：外周动脉支架治疗周围动脉硬化闭塞临床疗效好，但是目前没有一种完美的外周动脉支架，掌握各种支架的特点并灵活应用是取得良好疗效的关键。
目的：综述不同材料周围动脉支架置入治疗动脉硬化闭塞症的研究进展。
方法：应用计算机检索1968-01/2011-11 PubMed数据库相关文章，检索词为“stent”，并限定文章语言种类为English。共检索到文献107篇，最终纳入符合标准的文献40篇。
结果与结论：周围动脉支架置入治疗动脉硬化闭塞安全有效。支架材料主要有不锈钢支架、镍钛合金支架、钴基合金支架、钽金属支架、镁合金支架、高分子材料支架及多种材料复合支架。置入后支架内再狭窄是其主要并发症，支架断裂等并发症时有报道。支架置入后抗凝治疗已得到广泛认可。掌握各种支架的特点及适应证能提高支架的通畅率和减少支架置入后并发症。发展新型支架提高通畅率已成为将来研究方向。

关键词: 周围动脉, 支架置入, 动脉硬化闭塞症, 研究进展, 综述文献

Abstract:

BACKGROUND: The clinical effect of peripheral arterial stents in treating arteriosclerotic occlusive disease is good. But there is no perfect peripheral arterial stent up to now. To master the characteristics of various stents and flexible application is the key to good effect.
OBJECTIVE: To summarize the research progress of peripheral arterial stent placement in treating arteriosclerotic occlusive disease.
METHODS: A computer-based search was performed to retrieve PubMed from 1968-01 to 2011-11 using the keyword of “stent”. The language is restricted in English. Totally 107 articles were retrieved, and 40 articles met the requirement.
RESULTS AND CONCLUSION: Peripheral arterial stent placement in treating arteriosclerotic occlusive disease is safe and effective. The stent materials mainly include stainless steel, nickel titanium alloy, cobalt-based alloy, tantalum metal, magnesium alloy, high polymer material and variety of material compound stents. In-stent restenosis is the main complication. Postoperative complications such as stent fracture have been reported occasionally. Drug therapy has been widely accepted after stent implantation. To master the characteristics of various stents and indications can improve the patency rate and reduce the stent complication after stent placement. Development of new stents to improve patency rate has become the future research direction.

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