Early analgesic effect of cocktail periarticular injection versus femoral nerve block in total knee arthroplasty: a single-center randomized double-blind control

doi:10.3969/j.issn.2095-4344.2909

Abstract

Abstract:

BACKGROUND: It has been controversial whether the early analgesic effect and patient satisfaction of cocktail periarticular injection in total knee arthroplasty are better than femoral nerve block.

OBJECTIVE: To compare the early clinical effect with cocktail periarticular injection and femoral nerve block in total knee arthroplasty.

METHODS: From March to December 2019, 70 cases with chronic knee osteoarthritis were collected from Affiliated Hospital of Xuzhou Medical University. The patients were randomly divided into two groups. In the observation group (n=35), patients received total knee arthroplasty. Cocktail solution was injected into the posterior capsule, bilateral collateral ligament areas, and the subcutaneous tissue of the incision. After the incision was closed, cocktail solution was injected into the drainage tube. In the control group (n=35), patients received total knee arthroplasty. The femoral nerve block was performed after the incision was closed. Postoperative visual analogue scale scores for pain, knee active activity and analgesic satisfaction of patients were assessed within 14 days after surgery. The study was approved by ethics committee of Affiliated Hospital of Xuzhou Medical University.

RESULTS AND CONCLUSION: (1) At 2, 3 and 5 days postoperatively, the visual analogue scale pain scores of the observation group were significantly lower than those of the control group (P < 0.05); there was no significant difference at other time points (P > 0.05). (2) The knee flexion of observation group was statistically greater than control group at 2 and 3 days postoperatively (P < 0.05); there was no significant difference at other time points (P > 0.05). (3) Totally 23 of 35 patients in the observation group were satisfied with the analgesic effect and 10 of the 35 patients in the control group were satisfied with the analgesic effect. The differences between the groups were significant (P < 0.05). (4) Acute analgesia was observed 20 times in the observation group after operation, and 36 times in the control group. (5) The results showed that cocktail periarticular injection analgesia was superior to femoral nerve block analgesia in knee arthroplasty, which could improve the active motion and satisfaction of the knee in the early postoperative period. It was conducive to the early postoperative recovery of the knee.

Key words: bone, prosthesis, implants, knee arthroplasty, femoral nerve, block, analgesia, cocktail

CLC Number:

Zhang Ye, Feng Shuo, Zhang Yu, Sun Jianning, Shi Sifeng, Chen Xiangyang. Early analgesic effect of cocktail periarticular injection versus femoral nerve block in total knee arthroplasty: a single-center randomized double-blind control[J]. Chinese Journal of Tissue Engineering Research, 2020, 24(36): 5800-5805.

Figures/Tables 6

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