Hematopoietic stem cell transplantation: psychological characteristics and psychological support in recipients

doi:10.3969/j.issn.2095-4344.2015.06.028

Abstract

Abstract:

BACKGROUND: Hematopoietic stem cell transplantation is the main treatment for leukemia, lymphoma and other blood diseases, but there are various negative factors during the transplantation process that have important implications for the success of hematopoietic stem cell transplantation.
OBJECTIVE: To analyze the psychological characteristics of patients undergoing hematopoietic stem cell transplantation and to focus on the implementation effects of psychological intervention.
METHODS: From January 2012 to December 2013, totally 92 patients were admitted at the Hematopoietic Stem Cell Transplantation Center, the majority of whom had received autologous peripheral blood stem cell transplantation. Fifty-five of 92 patients were subjected to allogeneic stem cell transplantation, including 48 cases of relative sources and 7 of unrelated peripheral blood stem cell transplantation. Bone marrow suppression and composite grafting were carried out in some patients. According to the characteristics of negative factors at the different stages of stem cell transplantation, targeted interventional measures were performed, including psychological supports, prevention, observation and treatment of complications, and whole environmental protection programs.
RESULTS AND CONCLUSION: Hematopoietic stem cell transplantation was successfully implemented in all patients who had good compliance behaviors (medication, diet, and daily schedule), and had no the following adverse events: psychological stress, out of emotional control, destroying objects. No significant difference was found in the incidence of complications, the incidence of adverse events, and patient satisfaction rate during 2012-2013 (P > 0.05). Because the hematopoietic stem cell transplantation has strong specificity, patients need to strictly comply with the treatment path, stay long in laminar flow wards longer, and bear a greater psychological and physiological burden, whose behaviors are severely restricted. We should strictly implement aseptic standards, strengthen ward management and provide good guidance and support for patients, so as to reduce post-transplantation complications and ensure the successful completion of hematopoietic stem cell transplantation.

中国组织工程研究杂志出版内容重点：干细胞；骨髓干细胞；造血干细胞；脂肪干细胞；肿瘤干细胞；胚胎干细胞；脐带脐血干细胞；干细胞诱导；干细胞分化；组织工程

全文链接：

Key words: Hematopoietic Stem Cell Transplantation, Infection, Psychology

CLC Number:

R318

Zhao Yan-jie. Hematopoietic stem cell transplantation: psychological characteristics and psychological support in recipients[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(6): 980-984.

Figures/Tables 1

References

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