Effect of stent implantation and percutaneous transluminal angioplasty in the treatment of extracranial carotid artery stenosis

doi:10.3969/j.issn.2095-4344.2014.43.023

Abstract

Abstract:

BACKGROUND: Carotid artery stenting is a minimally invasive, safe, simple intervention, which is particularly meaningful to patients with carotid artery stenosis who exhibit poor physical basis and cannot tolerate open surgery.
OBJECTIVE: To explore the clinical effect of percutaneous transluminal angioplasty and stenting for treatment of extracranial carotid artery stenosis.
METHODS: Twenty-nine patients with extracranial carotid artery stenosis, including 19 males and 10 females, age ranging from 45-78 years, were enrolled and subjected to stenting and percutaneous angioplasty. American National Institutes of Health Stroke Scale, modified Rankin Scale and CT examination were tested before treatment and 24 hours after treatment. After 3-12 months follow-up, the coagulation indexes and B ultrasound of the carotid artery were reviewed.
RESULTS AND CONCLUSION: One patient exhibited the complete bifurcation occlusion of the right common carotid artery, and only the diameter of external carotid artery recovered 50.0%. The remaining patients were confirmed by angiograph that completely restored to normal levels, and the success rate was 97%. At 24 hours after treatment, all the 29 patients exhibit significant improvement in the diameter of lesioned carotid artery, scores on American National Institutes of Health Stroke Scale and modified Rankin Scale (P < 0.01, P < 0.05). During the 3-12 months follow-up, no cerebral infarction and transient cerebral ischemia occurred and carotid artery stenosis was improved in all patients. At 6 months after operation, one patient had restenosis, and the restenosis rate was 3%. Percutaneous angioplasty combined with biological material stenting for treatment of extracranial carotid artery stenosis can obtain good clinical effects.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

全文链接：

Key words: carotid stenosis, angioplasty, stents

CLC Number:

R318

Ma Ying, Liu Ye-song. Effect of stent implantation and percutaneous transluminal angioplasty in the treatment of extracranial carotid artery stenosis[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(43): 7023-7027.

Figures/Tables 2

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