中国组织工程研究 ›› 2017, Vol. 21 ›› Issue (3): 428-432.doi: 10.3969/j.issn.2095-4344.2017.03.019

• 骨与关节综述 bone and joint review • 上一篇    下一篇

3D打印技术在整形外科的研究及应用进展

何雪锋,熊爱兵   

  1. 西南医科大学附属医院整形烧伤外科,四川省泸州市   646000
  • 修回日期:2016-12-20 出版日期:2017-01-28 发布日期:2017-03-14
  • 通讯作者: 熊爱兵,教授,主任医师,硕士生导师,西南医科大学附属医院整形烧伤外科,四川省泸州市 646000
  • 作者简介:何雪锋,男,1991年生,四川省阆中市人,汉族,西南医科大学在读硕士,主要从事烧伤创面修复及整形重建的研究。

Application and research progress of three-dimensional printing in the field of orthopaedics   

He Xue-feng, Xiong Ai-bing   

  1. Department of Burn and Plastic Surgery, Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
  • Revised:2016-12-20 Online:2017-01-28 Published:2017-03-14
  • Contact: Xiong Ai-bing, Professor, Chief physician, Master’s supervisor, Department of Burn and Plastic Surgery, Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
  • About author:He Xue-feng, Studying for master’s degree, Department of Burn and Plastic Surgery, Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China

摘要:

文章快速阅读

 
 
文题释义
3D打印技术:3D打印技术诞生于20世纪80年代,是将计算机三维数字成像技术和多层次连续打印技术相结合的一种新兴应用技术,通过三维扫描、计算机辅助设计三维数字化模型,并对模型进行分层和数控编程,形成文件输入打印机,最终通过分层加工、叠加成型的方式,逐层增加材料来生成3D 实体模型。
再生医学:再生医学是一门研究如何促进创伤与组织器官缺损生理性修复,以及如何进行组织器官再生与功能重建的学科。目前实现组织器官再生的主要方法有3种:通过移植细胞悬浮体或聚合体来替代受损组织;实验室生产的能够替代天然组织的生物化人工组织或器官的植入;通过药物手段,对损伤组织部分进行再生诱导。
 
摘要
背景:3D生物打印利用组织工程及干细胞研究的成果,以活细胞及其他细胞活性成分作为打印原料,最终实现生物活性组织的打印和制作。
目的:对3D打印技术目前在整形外科的应用及研究进展作一综述。
方法:由第一作者检索从2007至2016 年PubMed 、Ovid、中国知网等数据库收录的关于3D打印技术在整形外科应用及研究进展的文献。英文检索词为“three-dimensional printing,3D printing, plastic and reconstructive surgery,orthopaedic, organ printing”,中文检索词为“3D打印,整形外科,修复重建,器官打印”,按纳入、排除标准筛选最终纳入44 篇文献进行分析、总结。

结果与结论:3D打印目前在颅颌面骨重建、耳鼻再造、皮肤打印及乳房重建等方面的应用较为广泛,特别在制作骨替代品及个性化假肢、假体方面技术已相当成熟。3D打印技术经历了从假体制作到生物活性打印的发展过程,最终有望进入器官打印阶段,彻底解决自体或同种异体移植所存在的局限。 

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程
ORCID: 0000-0002-5306-9920(何雪锋)

关键词: 骨科植入物, 骨植入物, 3D 打印技术, 整形外科, 骨软骨再生, 皮肤再生, 乳房重建, 个性化假体

Abstract:

BACKGROUND: Three-dimensional (3D) biological printing uses tissue engineering and stem cell research results, and takes living cells and other cell active ingredients as printing materials, finally realizing biological tissue printing and production. 

OBJECTIVE: To review the application and research progress of 3D printing in the field of orthopaedics.
METHODS: A computer-based search of PubMed, Ovid, and CNKI databases was performed for relevant literatures about application and research progress of 3D printing in the field of orthopaedics, all of which were published from 2007 to 2016. “three-dimensional printing, 3D printing, plastic and reconstructive surgery, orthopaedic, organ printing” were used as keywords during the searching process. According to inclusion and exclusion criteria, 44 articles were included for further analysis and summary.
RESULTS AND CONCLUSION: 3D printing was mainly applied into craniomaxillofacial reconstruction, nose, ear and cartilage reconstruction, breast reconstruction, and skin printing. Its application in bone and prosthetic fabrication was quite mature. Based on the development of 3D printing from prosthetic fabrication to bioactive printing, organ printing will eventually become reality to completely solve the autologous or allograft transplantation limitations. 

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程

Key words: 3D Printing, Regenerative Medicine, Tissue Engineering

中图分类号: