中国组织工程研究

中国组织工程研究 ›› 2026, Vol. 30 ›› Issue (23): 6040-6050.doi: 10.12307/2026.312

• 组织工程相关大数据分析 Big data analysis in tissue engineering • 上一篇    下一篇

骨质疏松性椎体压缩骨折：研究现状与发展趋势的可视化分析

曲泊霖1，次仁伦珠2，郭锦阳1，3，孟寒露4，丁冠翔1，5，桑洪鹏1   

  1. 1赤峰学院附属医院，内蒙古自治区赤峰市   024000；2山南市人民医院，西藏自治区山南市   856000；3内蒙古民族大学，内蒙古自治区通辽市 028000；4通辽市人民医院，内蒙古自治区通辽市   028000；5内蒙古科技大学包头医学院，内蒙古自治区包头市   014000
  • 收稿日期:2025-04-22 接受日期:2025-06-05 出版日期:2026-08-18 发布日期:2025-12-31
  • 通讯作者: 桑洪鹏，主任医师，赤峰学院附属医院，内蒙古自治区赤峰市 024000
  • 作者简介:曲泊霖，男，1988年生，内蒙古自治区赤峰市人，汉族，硕士，主治医师，主要从事与脊柱疾病诊疗相关的临床及基础性研究。
  • 基金资助:
    山南市科技计划项目(SNSBJKJJHXM2023015)，项目名称：金天格胶囊治疗高原地区骨质疏松性桡骨远端骨折的应用研究，项目负责人：次仁伦珠；内蒙古医学科学院公立医院科研联合基金项目(2024GLLH1015)，项目名称：颈后路单开门椎板成形术最佳开门参数确定及验证的临床与基础研究，项目负责人：桑洪鹏；赤峰市自然科学科研课题项目(SZR2022144)，项目名称：骨质疏松性椎体压缩性骨折椎体强化术后再骨折特点及危险因素研究，项目负责人：桑洪鹏

Osteoporotic vertebral compression fractures: a visual analysis of current status and emerging trends

Qu Bolin1, Ciren Lunzhu2, Guo Jinyang1, 3, Meng Hanlu4, Ding Guanxiang1, 5, Sang Hongpeng1   

  1. 1Affiliated Hospital of Chifeng University, Chifeng 024000, Inner Mongolia Autonomous Region, China; 2Shannan People's Hospital, Shannan 856000, Tibet Autonomous Region, China; 3Inner Mongolia Minzu University, Tongliao 028000, Inner Mongolia Autonomous Region, China; 4Tongliao People’s Hospital, Tongliao 028000, Inner Mongolia Autonomous Region, China; 5Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou 014000, Inner Mongolia Autonomous Region, China
  • Received:2025-04-22 Accepted:2025-06-05 Online:2026-08-18 Published:2025-12-31
  • Contact: Sang Hongpeng, Chief physician, Affiliated Hospital of Chifeng University, Chifeng 024000, Inner Mongolia Autonomous Region, China
  • About author:Qu Bolin, MS, Attending physician, Affiliated Hospital of Chifeng University, Chifeng 024000, Inner Mongolia Autonomous Region, China
  • Supported by:
    Shannan Science and Technology Program Project, No. SNSBJKJJHXM2023015 (to CL); Public Hospital Scientific Research Joint Fund Project of Inner Mongolia Academy of Medical Sciences, No. 2024GLLH1015 (to SHP); Chifeng Natural Science Research Project, No. SZR2022144 (to SHP)

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摘要：



文题释义：
骨质疏松性椎体压缩骨折：指因原发性骨质疏松症引起脊柱椎体骨密度或骨质量降低，进而导致骨强度不足，在轻微创伤或无明显创伤时椎体发生压缩性骨折，主要表现为腰背部疼痛，伴或不伴下肢神经症状。椎体骨折后患者活动量减少，导致骨质疏松症进一步加重，增加脊柱再次骨折或其他部位骨折的风险。
文献计量学：是一种定量分析学术文献的方法，通过对文献的数量、分布和被引情况等进行统计和分析，揭示文献的分布规律、发展趋势及学术影响力，为科研管理、学科评估、政策制定等提供科学依据。文献计量学广泛应用于科研评价、学术影响力分析、科研合作网络构建、热点领域识别等。

背景：目前文献多集中于多种手术方式治疗骨质疏松性椎体压缩骨折临床效果及手术安全性的比较，缺乏关于骨质疏松性椎体压缩骨折治疗与预后研究现状、研究热点及未来发展趋势的研究报道。
目的：通过文献计量学方法分析骨质疏松性椎体压缩骨折领域的研究现状、热点及发展趋势。
方法：在Web of Science核心数据库中检索1994-2023年期间发表的骨质疏松性椎体压缩骨折治疗及预后相关英文文献，采用CiteSpace与VOSviewer 对出版物数量、国家/地区分布、研究机构、期刊来源、作者贡献、关键词频率、研究热点及最具影响力文献进行文献计量学与可视化分析，探讨骨质疏松性椎体压缩骨折领域的研究热点及发展趋势。
结果与结论：研究纳入2 275篇文献，骨质疏松性椎体压缩骨折全球研究发表量逐年增加，2022年发文量最多，共发表文章215篇。文献涵盖全球68个国家/地区，其中中国共发表644篇文献，位居首位，苏州大学是发表论文最多的机构，共计90篇。《European Spine Journal》(n=146)是发文量最多的期刊，《Spine》的被引频次(n=1 923)、篇均被引次数(58.5)及H指数(45)均处于首位，发文量(n=106)位列第2。Yang, Huilin是发文量最多的作者(n=65)，法国医生Galibert, P的被引频次最高(n=300)。研究热点早期主要集中在“vertebroplasty(椎体成形术)”“balloon kyphoplasty(球囊扩张椎体成形术)”“polymethylmethacrylate(聚甲基丙烯酸甲酯)”等，中期则转向“surgical management(手术治疗)”“nonoperative treatment(非手术治疗)”等，近年来研究重点进一步扩展到“safety(安全性)”“risk factors(危险因素)”等，并将继续作为未来研究的趋势获得持续关注。
https://orcid.org/0000-0002-8127-1202 (曲泊霖) 


中国组织工程研究杂志出版内容重点：干细胞；骨髓干细胞；造血干细胞；脂肪干细胞；肿瘤干细胞；胚胎干细胞；脐带脐血干细胞；干细胞诱导；干细胞分化；组织工程

关键词: 文献计量学, 可视化分析, 骨质疏松性椎体压缩骨折, 治疗, 预后, VOSviewer, CiteSpace

Abstract: BACKGROUND: Current literature primarily focuses on comparing the clinical efficacy and surgical safety of various operative approaches for osteoporotic vertebral compression fractures, while there is a notable lack of research addressing the current status, hotspots, and future trends in the treatment and prognosis of osteoporotic vertebral compression fractures.
OBJECTIVE: To analyze the current status, hotspots and trends of research on osteoporotic vertebral compression fractures by bibliometric methods.
METHODS: English articles related to the treatment and prognosis of osteoporotic vertebral compression fractures published between 1994 and 2023 were retrieved from the Web of Science Core Collection. Bibliometric and visualization analyses were conducted using CiteSpace and VOSviewer to evaluate publication volume, geographic distribution, institutional contributions, journal rankings, author productivity, keyword co-occurrence, research hotspots, and citation impact, thereby exploring the hotspots and trends of research on osteoporotic vertebral compression fractures.
RESULTS AND CONCLUSION: A total of 2 275 publications were analyzed. Global research output of osteoporotic vertebral compression fractures demonstrated a steady upward trajectory, peaking in 2022 with 215 publications. Contributions spanned 68 countries/regions, with China leading in productivity (644 publications). Soochow University emerged as the most prolific institution (90 publications). European Spine Journal ranked first in publication volume (n=146), while Spine exhibited the highest citation count (n=1 923), citations per article (58.5), and H-index (45), ranked second in publication volume (n=106). Yang Huilin (China) was the most productive author (n=65), whereas Galibert P (France) received the highest citation count (n=300). Research themes evolved dynamically: early-stage focus centered on “vertebroplasty,” “balloon kyphoplasty,” and “polymethylmethacrylate (PMMA)”; mid-term shifts emphasized “surgical management” and “nonoperative treatment”; and recent expansion prioritized “safety” and “risk factors,” which will continue to gain sustained attention as a trend for future research.


Key words: bibliometrics, visual analysis, osteoporotic vertebral compression fractures, treatment, prognosis, VOSviewer, CiteSpace

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