中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (37): 6913-6916.doi: 10.3969/j.issn.1673-8225.2010.37.017

• 组织构建实验造模 experimental modeling in tissue construction • 上一篇    下一篇

间歇性低氧训练复合运动训练模型大鼠的造血功能

汝铁林1，郝选明2   

  1. 1 西安科技大学体育部，陕西省西安市  710054；2 华南师范大学体育科学学院，广东省广州市  510631
  • 出版日期:2010-09-10 发布日期:2010-09-10
  • 作者简介:汝铁林★，男，1976年生，陕西省韩城市人，汉族，2010年西安体育学院毕业，硕士，讲师，主要从事运动人体科学方面的研究。 rtl_7608@yeah.net

Hematopoietic function of model rats under intermittent hypoxic training and exercise

Ru Tie-lin1, Hao Xuan-ming2   

  1. 1 Department of Physical Education, Xi’an University of Science and Technology, Xi’an 710054, Shaanxi Province, China; 2 College of Sports Science, South China Normal University, Guangzhou   510631, Guangdong Province, China
  • Online:2010-09-10 Published:2010-09-10
  • About author:Ru Tie-lin★, Master, Lecturer, Department of Physical Education, Xi’an University of Science and Technology, Xi’an 710054, Shaanxi Province, China rtl_7608@yeah.net

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460

被引次数

2

摘要：

背景：已有的研究显示低氧训练能够通过改善血液学指标提高有氧运动能力，但对于不同间歇低氧训练模式对血液学指标影响的研究较少。
目的：研究间歇性低氧训练对大鼠造血功能的影响。
方法：将雄性SD大鼠96只随机分为4组：低氧组和运动组分别进行间歇性低氧训练和游泳训练；低氧+运动组间歇性低氧训练和游泳训练同时进行；对照组自由活动和摄食。各组进行正式训练4周，分别于正式训练1，2，3，4周训练结束后24 h，取尾静脉血，检测大鼠血红蛋白、红细胞、及红细胞压积水平。 
结果与结论：经过4周训练后，3种干预模式对大鼠血常规指标都有不同程度的影响，但低氧+运动组大鼠血红蛋白、红细胞、及红细胞压积指标改善最为显著。提示间歇性低氧训练复合运动训练在改善大鼠造血功能方面优于单独间歇性低氧训练或运动训练。

关键词: 间歇性低氧训练, 运动训练, 血红蛋白, 红细胞计数, 红细胞压积, 造血功能

Abstract:

BACKGROUND: Previous studies have demonstrated that hypoxic training can promote aerobic capacity by improving hematological indexes, but the effects of different intermittent hypoxic training models on hematological indexes are rarely reported.
OBJECTIVE: To investigate the effect of intermittent hypoxic training on hematopoietic function in rats.
METHODS: A total of 96 SD rats were randomly divided into 4 groups: intermittent hypoxic training group, swimming group, intermittent hypoxic training + swimming group, and control group. Intermittent hypoxic training group and swimming group underwent intermittent hypoxic training and swimming training respectively; intermittent hypoxic training and swimming training were carried out simultaneously in intermittent hypoxic training +swimming group; control group underwent freely moving and feeding. All groups underwent formal training for 4 weeks. Twenty-four hours after 1-, 2-, 3-, 4- week formal training, blood sample from tail vein was collected to detect hemoglobin, red blood corpuscle, and hematocrit levels.
RESULTS AND CONCLUSION: After 4-week training, three types of intervention models have different effects on routine blood indexes; however, hemoglobin, red blood corpuscle, and hematocrit levels changed most significantly in intermittent hypoxic training + swimming group. It is indicated that intermittent hypoxic training and exercise are superior to intermittent hypoxic training or exercise training in case of improving hematopoietic function of rats.

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