中国组织工程研究

中国组织工程研究 ›› 2013, Vol. 17 ›› Issue (17): 3124-3131.doi: 10.3969/j.issn.2095-4344.2013.17.012

• 骨与关节图像与影像 bone and joint imaging • 上一篇    下一篇

MRI DWI序列显示健康志愿者骶髂关节成像的最佳b值

李贝贝1，任翠萍1，李 莹1，石晓莹1，任 仙2   

  1. 1郑州大学第一附属医院磁共振科，河南省郑州市 450052
    2郑州大学，河南省郑州市 450000
  • 收稿日期:2012-10-15 修回日期:2012-11-30 出版日期:2013-04-23 发布日期:2013-04-23
  • 通讯作者: 任翠萍，主任医师，教授，郑州大学第一附属医院磁共振科，河南省郑州市 450052 rcp810@sohu.com
  • 作者简介:李贝贝★，女，1988年生，河南省周口市太康县人，汉族，郑州大学在读硕士，主要从事骨骼肌肉系统MRI诊断的研究。 lixichunbaby@163.com
  • 基金资助:

    河南省科技攻关计划项目

Magnetic resonance diffusion weighted imaging sequence shows the best b value of sacroiliac joint imaging of healthy volunteers

Li Bei-bei1, Ren Cui-ping1, Li Ying1, Shi Xiao-ying1, Ren Xian2   

  1. 1 Department of Magnetic Resonance, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China
    2 Zhengzhou University, Zhengzhou 450000, Henan Province, China
  • Received:2012-10-15 Revised:2012-11-30 Online:2013-04-23 Published:2013-04-23
  • Contact: Ren Cui-ping, Chief physician, Professor, Department of Magnetic Resonance, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China rcp810@sohu.com
  • About author:Li Bei-bei★, Studying for master’s degree, Department of Magnetic Resonance, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China lixichunbaby@163.com

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摘要：

背景：MRI DWI序列是一种简单易行、特异性较强、敏感度较高且能早期诊断活动性骶髂关节炎、监测其活动性的检查方法之一，但DWI序列对骶髂关节显示的最佳b值尚无统一标准。
目的：通过比较10-20岁健康志愿者骶髂关节MRI不同b值时DWI及表观弥散系数差异，寻找MRI DWI序列显示骶髂关节的最佳b值。 
方法：随机选择21名10-20岁无骶髂关节疾病的健康志愿者作为研究对象，行骶髂关节轴位T1WI、STIR及DWI扫描(b值为0，300，600，900 s/mm2)，观察不同b值对骶髂关节的显示情况，对图像进行评价；同时，分别测量双侧骶髂关节的骶侧、髂侧关节旁骨髓的表观弥散系数，对不同b值双侧骶髂关节旁骨髓表观弥散系数进行统计学分析。  
结果与结论：21名健康志愿者42个骶髂关节在b值为300，600 s/mm2时，图像显示清晰，对比度好，能清晰显示骶髂关节关节。b值为900 s/mm2时，图像伪影较大，图像质量模糊，对比度差，无法完成表观弥散系数值的测量。b值为600 s/mm2时，双侧骶髂关节旁骨髓所测得的表观弥散系数值变化范围小，而b值为300 s/mm2时，表观弥散系数值差异性较大。结果显示600 s/mm2是MRI DWI序列显示骶髂关节的最适宜b值，不仅能清晰显示双侧骶髂关节，而且所测得关节旁骨髓的表观弥散系数值精确度较高。

关键词: 骨关节植入物, 骨与关节图像与影像, 10-20岁, 健康志愿者, 强直性脊柱炎, 骶髂关节, 磁共振成像, DWI, 表观弥散系数, b值, 对照研究, 省级基金

Abstract:

BACKGROUND: Magnetic resonance diffusion weighted imaging sequence is one of the inspection methods which is simple to operation, has strong specificity and high sensitive and can early diagnose the active sacroiliitis and monitoring the activities, but there is no standard of b values of sacroiliac joint displayed with diffusion weighted imaging sequence.
OBJECTIVE: To find the best b value displayed with magnetic resonance diffusion weighted imaging sequence through comparing the difference of diffusion weighted imaging and apparent diffusion coefficient between the healthy volunteers aged 10-20 years old under different b values of sacroiliac joint.
METHODS: Twenty-one healthy volunteers without sacroiliac joint diseases, aged 10-20 years old were collected for research. All the health volunteers were taken MRI scan with several sequences (T1WI, STIR, DWI: b=300 s/mm2, 600 s/mm2, 900 s/mm2). The sacroiliac joint displayed under different b values was observed, and the images were evaluated. Meanwhile, the apparent diffusion coefficient of the sacral side and iliac side joint surrounding bone marrow of bilateral sacroiliac joint was measured, and the statistical analysis of apparent diffusion coefficient of sacroiliac joint surrounding bone marrow was performed under different b values.
RESULTS AND CONCLUSION: Clear images with high contrast ratio of 21 healthy volunteers (42 sacroiliac joints) could clearly show the sacroiliac joints when the b values were 300 s/mm2 and 900 s/mm2. When the b value was 900 s/mm2, the images had larger image artifacts, fuzzy image quality and poor contrast ration that unable to complete the measurement of the apparent diffusion coefficient values. When the b value was 600 s/mm2, the change of apparent diffusion coefficient of sacroiliac joint surrounding bone marrow was small, while the b value was 300 s/mm2, the difference of apparent diffusion coefficient of sacroiliac joint was significant. The b value of 600 s/mm2 is the best b value for magnetic resonance diffusion weighted imaging sequence to display the sacroiliac joint which can clearly show the bilateral sacroiliac joint, and the apparent diffusion coefficient of bilateral sacroiliac joint surrounding bone marrow measured with the b value has higher accuracy.

Key words: bone and joint implants, photographs and images of bone and joint, 10-20 years old, healthy volunteer, ankylosing spondylitis, sacroiliac joint, magnetic resonance imaging, diffusion weighted imaging, apparent diffusion coefficient, b value, comparative study, provincial grants-supported paper

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