中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (16): 3025-3028.doi: 10.3969/j.issn.1673-8225.2012.16.039

• 生物材料临床实践 clinical practice of biomaterials • 上一篇    下一篇

聚乳酸防粘连膜在肌腱修复中的应用★

徐海栋，赵建宁，卢俊浩，刘金龙，陈  勇   

  1. 解放军南京军区南京总医院骨科，江苏省南京市  210002
  • 收稿日期:2011-10-01 修回日期:2011-12-07 出版日期:2012-04-15 发布日期:2012-04-15
  • 通讯作者: 陈勇，硕士，副主任医师，副教授，解放军南京军区南京总医院骨科，江苏省南京市 210002 13813889089@ 139.com
  • 作者简介:徐海栋★，男，1980年生，安徽省安庆市人，汉族，2009年解放军第二军医大学毕业，硕士，主治医师，讲师，主要从事脊柱外科与生物材料的研究。xuhaidong1980@163.com

Application of poly (D, L-lactic acid) absorbable medical film in tendon repair

Xu Hai-dong, Zhao Jian-ning, Lu Jun-hao, Liu Jin-long, Chen Yong   

  1. Department of Orthopedics, Nanjing General Hospital of Nanjing Military Command, Nanjing  210002, Jiangsu Province, China
  • Received:2011-10-01 Revised:2011-12-07 Online:2012-04-15 Published:2012-04-15
  • Contact: Chen Yong, Master, Associate chief physician, Associate professor, Department of Orthopedics, Nanjing General Hospital of Nanjing Military Command, Nanjing 210002, Jiangsu Province, China 13813889089@139.com
  • About author:Xu Hai-dong★, Master, Attending physician, Lecturer, Department of Orthopedics, Nanjing General Hospital of Nanjing Military Command, Nanjing 210002, Jiangsu Province, China xuhaidong1980@163.com

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摘要：

背景：如何使肌腱修复后少发生或不发生粘连，尽快实现其滑动功能又不影响肌腱本身的愈合？
目的：观察聚乳酸防粘连膜在肌腱损伤修复后的防粘连效果。
方法：选择解放军南京军区南京总医院骨科收治的手部屈伸肌腱断裂患者60例(共95根肌腱)，随机分为2组。生物防粘连膜组采用弘健医用膜包裹吻合口1.5~2.0 cm；对照组不使用生物防粘连膜。修复后6个月屈肌腱采用TAM系统评定，伸肌腱采用Miller分级法评定，比较其综合优良率。
结果与结论：修复后均随访达半年以上，生物防粘连膜组综合优良率为90%(45/50)，高于对照组综合优良率67%(30/45)   (P < 0.05)。提示聚乳酸防粘连膜临床应用简单便捷，有效降低了肌腱修复后粘连的形成，临床疗效肯定。
 

关键词: 聚乳酸, 肌腱修复, 肌腱粘连, 疗效, 肌腱功能

Abstract:

BACKGROUND: The present studies are focused on how to reduce or eliminate adhesion after tendon repair to fulfill sliding function soon without affecting the healing of tendon.
OBJECTIVE: To observe the anti-adhesion effects of poly (D, L-lactic acid) (PDLLA) absorbable medical film on tendon repair.
METHODS: Sixty patients with flexor tendon and stretch tendon rupture (95 tendons) in hand selected from Nanjing General Hospital of Nanjing Military Region were randomly divided into two groups. Anastomosis 1.5-2.0 cm was wrapped by using Hongjian medical membrane in anti-adhesion biomembrance group, while control group did not use biological absorbable medical film. At 6 months after repair, flexor tendon and stretch tendon were detected by using total active movement system and Miller classification respectively for the comparison of comprehensive good rate.
RESULTS AND CONCLUSION: The comprehensive good rate in the anti-adhesion biomembrance group (90%, 45/50) was higher than that in the control group (67%, 30/45) during over 6-month follow-up after repair. It is indicated that the clinical application of PDLLA absorbable medical film is easy and convenient to reduce postoperative adhesion effectively after tendon repair, and its clinical effects are confirmed.
 

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