中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (48): 9051-9054.doi: 10.3969/j.issn.1673-8225.2011.48.030

• 骨与关节损伤基础实验 basic experiments of bone and joint injury • 上一篇    下一篇

体描箱评价脊柱侧弯幼儿的肺功能变化

丁  静，吴美思，赵德育，刘  娜   

  1. 南京医科大学附属南京儿童医院肺功能室，江苏省南京市  210008
  • 收稿日期:2011-03-18 修回日期:2011-08-11 出版日期:2011-11-26 发布日期:2011-11-26
  • 作者简介:丁静，女，1982年生，江苏省泰州市人，汉族，2005年东南大学医学院毕业，医师，主要从事小儿呼吸系统疾病与肺功能方面的研究。 dingjing10@sina.com

Pulmonary function changes in scoliosis children evaluated by bodyplethysmography

Ding Jing, Wu Mei-si, Zhao De-yu, Liu Na   

  1. Laboratory of Pulmonary Function, Affiliated Nanjing Children’s Hospital of Nanjing Medical University, Nanjing  210008, Jiangsu Province, China
  • Received:2011-03-18 Revised:2011-08-11 Online:2011-11-26 Published:2011-11-26
  • About author:Ding Jing, Physician, Laboratory of Pulmonary Function, Affiliated Nanjing Children’s Hospital of Nanjing Medical University, Nanjing 210008, Jiangsu Province, China dingjing10@sina.com

PDF

628

被引次数

12

摘要：

背景：肺功能检查是脊柱侧弯矫正前评价手术风险的重要手段，寻找一种简便、有效的检测肺功能评估方法是低龄儿童脊柱侧弯手术时机选择及治疗效果评价的迫切要求。
目的：应用体描箱评价脊柱侧弯幼儿的肺功能变化。
方法：纳入脊柱侧弯患儿31例，健康对照幼儿50例。采用德国耶格公司生产的婴儿体描箱进行肺功能指标检测，包括潮气量、分钟通气量、达峰容积比、达峰时间比、潮气呼气峰流速、25%，50%，75%潮气量时的潮气呼气流速、呼吸频率、功能残气量及有效气道阻力。
结果与结论：脊柱侧弯组患儿功能残气量明显低于健康组(P < 0.01)，有效气道阻力明显高于健康组(P < 0.01)，分钟通气量、潮气呼气峰流速及75%潮气量时的潮气呼气流速均明显低于健康组(P < 0.05)。提示功能残气量、有效气道阻力是体描箱测定的经典指标，脊柱侧弯患儿功能残气量明显减低，气道阻力明显增高。体描箱可作为检测低龄脊柱侧弯患儿肺功能的重要手段。

关键词: 体描箱, 脊柱侧弯, 肺功能, 功能残气量, 气道阻力

Abstract:

BACKGROUND: Pulmonary function test is the important method of evaluating the risk before scoliosis correction. In search of a convenient and effective method to estimate pulmonary function is the urgent demand of choosing surgical time and evaluating the therapeutic efficacy for scoliosis in children.
OBJECTIVE: To estimate the pulmonary function changes of scoliosis children with bodyplethysmography.
METHODS: Thirty-one children with scoliosis and fifty healthy children were enrolled in the study. The parameters included tidal volume (VT), minute volume (MV), ratio of volume to peak expiratory flow (PEF) to total expiratory volume (VPTEF/VE), ratio of time to PEF to total expiratory time (tPTEF/tE), tidal PEF, as well as tidal expiratory flow (TEF) at 25%, 50% and 75% VT, respiratory rate (RR), function capacity (FRCp), and effective resistance (Reff).
RESULTS AND CONCLUSION: In comparison with the healthy group, FRCp was obviously decreased in scoliosis children (P < 0.01), Reff was increased significantly (P < 0.01), MV, tidal PEF and TEF at 75% VT were increased. FRCp and Reff were classical indexes of bodyplethysmography. Reff was significantly increased and FRCp was significantly decreased in scoliosis children. Bodyplethysmography can be used as an important method in measuring pulmonary function of underage children with scoliosis.

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