中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (37): 7023-7026.doi: 10.3969/j.issn.1673-8225.2011.37.043

• 组织构建临床实践 clinical practice in tissue construction • 上一篇    下一篇

贵阳地区成人骨密度与骨质疏松症调查

冯小波1,王世伟2,刘文波1,黄  希2,廖永芳1,何桂群1,刘洪举1,胡志俊2   

  1. 1贵州省骨科医院,贵州省贵阳市 550007
    2 上海中医药大学附属龙华医院,上海市 200032
  • 收稿日期:2011-03-16 修回日期:2011-03-22 出版日期:2011-09-10 发布日期:2011-09-10
  • 通讯作者: 胡志俊,博士,副教授,主要从事中医药对骨退行性变的康复研究。上海中医药大学附属龙华医院,上海市 200032 unstoppablestone007@yahoo. com.cn
  • 作者简介:冯小波★,男,1977年生,硕士,主治医师,主要从事中医药防治骨与关节退行性疾病shiwei050515@ 126.com
  • 基金资助:

    上海市科学技术委员会2008年上海市参与西部开发科技合作项目(08495802000),贵阳地区成人骨密度变化规律的测定及骨质疏松症的中医辨证分型研究。

Bone mineral density in an adult population with osteoporosis from Guiyang area

Feng Xiao-Bo1, Wang Shi-wei2, Liu Wen-bo1, Huang Xi2, Liao Yong-fang1, He Gui-qun1, Liu Hong-ju1, Hu Zhi-jun2   

  1. 1Hospital of Orthopedics of Guizhou Province, Guiyang   550007, Guizhou Province, China
    2 Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
  • Received:2011-03-16 Revised:2011-03-22 Online:2011-09-10 Published:2011-09-10
  • Contact: Hu Zhi-jun, Doctor, Associate professor, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China unstoppablestone007@yahoo.com.cn
  • About author:Feng Xiao-bo★, Master, Attending physician, Hospital of Orthopedics of Guizhou Province, Guiyang 550007, Guizhou Province, China shiwei050515@126 com
  • Supported by:

    2008 Shanghai Science and Technology Cooperation Program regarding Western Area Development of Shanghai Committee of Science and Technology*

摘要:

背景:中国很多地方做过骨密度的变化规律及骨质疏松症的调查,但对于地处西部的贵阳地区,尚缺乏对的骨密度变化规律和骨质疏松症全面系统的随机调查。
目的:调查贵阳地区成人骨密度,为该地区骨质疏松的预防、诊断、治疗提供参考依据。
方法:2008/2011用双能X射线骨密度仪对贵阳地区共1 334例年龄为20~79岁的人群进行骨密度测定,测定部位包括腰椎1~4椎体、右股骨近端,以峰值骨密度减低2. 0 SD为诊断骨质疏松症标准,按性别、10岁一个年龄分组进行统计学分析。
结果与结论:贵阳地区男、女骨密度峰值均在20~29岁年龄组,女性50岁、男性60岁以后骨密度值明显降低。20~29岁的女性人群中出现骨质疏松症发病率和骨丢失率较高的异常现象。提示对于女性小于50岁和男性小于60岁,应加强普及骨质疏松预防知识,50岁以上的女性和60岁以上的男性还应同时采取相应干预措施,以减少骨质疏松症的发生,同时该调查为贵阳地区骨质疏松症的诊治提供了参考依据。

关键词: 贵阳地区, 骨密度, 骨质疏松症, 双能X线骨密度仪, 组织工程

Abstract:

BACKGROUND: Investigation regarding bone mineral density (BMD) change rule and osteoporosis in many areas of China has been much reported. However, studies regarding BMD change rule and osteoporosis in Guiyang area, China have been rarely reported.
OBJECTIVE: To investigate BMD in adult population in Guiyang area, China and provide the basis for prevention, diagnosis and treatment of osteoporosis.
METHODS: BMD was measured in 1 334 cases aged 20-79 years from Guiyang area using dual-energy X-ray absorptiometry during 2008-2011. The measurement sites included lumbar vertebrae 1 to 4 lumbar spine, right proximal femur. The peak BMD reduced by 2.0 SD was taken as the diagnosis for osteoporosis. Statistical analysis was performed based on 10-year age group according to gender.
RESULTS AND CONCLUSION: The peak BMDs of 60 men and 50 women from Guiyang area appeared in age group of 20-29. Female population aged 20-29 years showed a high incidence of osteoporosis and bone loss. These findings suggest that awareness of osteoporosis prevention should be enhanced for women before 50 years old and men before 60 years old, while for the subsequent years, relevant interventions should be taken to reduce osteoporosis incidence.

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