中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (34): 6403-6406.doi: 10.3969/j.issn.1673-8225.2011.34.033

• 生物材料综述 biomaterial review • 上一篇    下一篇

涂层材料及技术在医学临床领域的应用

庞  瑜1,张国浩2,程丑夫1   

  1. 1湖南中医药大学第一附属医院,湖南省长沙市  410007
    2佛山市顺德区均安医院内一科,广东省佛山市  528329
  • 收稿日期:2011-02-11 修回日期:2011-05-10 出版日期:2011-08-20 发布日期:2011-08-20
  • 通讯作者: 程丑夫,主任医师,教授,湖南中医药大学第一附属医院,湖南省长沙市 410007
  • 作者简介:庞瑜,女,1982年生,重庆市人,汉族,2011年湖南中医药大学毕业,上海中医药大学附属龙华医院,医师,主要从事心血管疾病中医药防治的研究。 blue99284841@163.com

Coating materials and technologies in clinic

Pang Yu1, Zhang Guo-hao2, Cheng Chou-fu1   

  1. 1First Affiliated Hospital, Hunan University of Traditional Chinese Medicine, Changsha  410007, Hunan Province, China
    2First Department of Internal Medicine, Jun’an Hospital of Shunde District, Foshan  528329, Guangdong Province, China
  • Received:2011-02-11 Revised:2011-05-10 Online:2011-08-20 Published:2011-08-20
  • Contact: Cheng Chou-fu, Chief physician, Professor, First Affiliated Hospital, Hunan University of Traditional Chinese Medicine, Changsha 410007, Hunan Province, China
  • About author:Pang Yu, Studying for doctorate, Physician, First Affiliated Hospital, Hunan University of Traditional Chinese Medicine, Changsha 410007, Hunan Province, China blue99284841@163.com

摘要:

背景:涂层材料及技术已在人们的生产生活中广泛应用,在医学领域里也得到了蓬勃发展。
目的:综述涂层材料及技术在医学领域中的应用进展。
方法:应用计算机检索2000-01/2010-12万方数据库相关文章,检索词“涂层,医学,应用”,并限定文章语言种类为中文。同时计算机检索2000-01/2010-12 PubMed数据库相关文章,检索词“coating,medicine,application”,并限定文章语言种类为English。共检索到文献614篇,最终纳入符合标准的文献30篇。
结果与结论:涂层技术在生活的方方面面都有应用,在医学领域里的应用也日渐蓬勃,目前研制出了很多生物相容性好排斥反应小的涂层材料并应用于临床。文章分别从口腔、体外循环、骨科等领域对涂层支架进行介绍,发现开发新的涂层药物,寻找更加合理有效的药物组合,可能会使药物涂层支架的治疗作用产生质的飞跃。

关键词: 涂层, 医学, 应用, 生物活性涂层材料, 综述文献

Abstract:

BACKGROUND: Coating materials and production technology in people's lives have been widely used, as well as in the medical field has also been booming.
OBJECTIVE: To review the applications coating materials and technology applications in the medical field.
METHODS: We searched from January 2000 to December 2010 Wanfanga database for related articles, and the key words were "coating, medicine, application", and the language was limited to Chinese. A total of 506 documents retrieved. PubMed database was also searched from January 2000 to December 2010 for related articles, the key words were "coating, medicine, application" and the language was limited to English. 108 documents were retrieved. Finally, 30 papers were included in result analysis.
RESULTS AND CONCLUSION: The coating technology has been applied in all aspects of life. Its application in the medical field has become more prosperous, and has developed a lot of coating materials with good biocompatibility and less rejection applied in clinical area. This paper introduces different coating stents in the stomatology, cardiopulmonary bypass, orthopedics in order to develop new coating materials and more rational and effective drug combinations, based on which drug-eluting stent treatment may produce a qualitative leap.

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