中国组织工程研究

中国组织工程研究 ›› 2025, Vol. 29 ›› Issue (11): 2394-2401.doi: 10.12307/2025.354

• 组织构建综述 tissue construction review • 上一篇    下一篇

运动对大学生肠道菌群影响的系统综述

刘昭志1，2，黄  丽1，2，田浩冬1，2，李  岚1，2，陈  晓3，陶云飞1，2，彭  莉1，2   

  1. 西南大学，1体育学院，2体育学院国家体育总局体质评价与运动机能监控重点实验室，重庆市  400715；3山东中医药大学健康学院，山东省济南市  250000
  • 收稿日期:2024-03-22 接受日期:2024-05-18 出版日期:2025-04-18 发布日期:2024-08-12
  • 通讯作者: 彭莉，博士，教授，博士生导师，西南大学，体育学院，体育学院国家体育总局体质评价与运动机能监控重点实验室，重庆市 400715
  • 作者简介:刘昭志，男，2000年生，汉族，西南大学体育学院在读硕士，主要从事慢性病运动防治的研究。
  • 基金资助:
    国家社科基金项目(21BTY092)，项目负责人：彭莉；重庆市体育局一般项目(B202206)，项目负责人：黄丽

Effects of exercise intervention on intestinal flora in college students: a systematic review

Liu Zhaozhi1, 2, Huang Li1, 2, Tian Haodong1, 2, Li Lan1, 2, Chen Xiao3, Tao Yunfei1, 2, Peng Li1, 2     

  1. 1School of Physical Education, 2Key Laboratory of Physical Fitness Evaluation and Exercise Performance Monitoring of the General Administration of Sport of China, School of Physical Education, Southwest University, Chongqing 400715, China; 3School of Health, Shandong University of Traditional Chinese Medicine, Jinan 250000, Shandong Province, China
  • Received:2024-03-22 Accepted:2024-05-18 Online:2025-04-18 Published:2024-08-12
  • Contact: Peng Li, PhD, Professor, Doctoral supervisor, School of Physical Education, Southwest University, Chongqing 400715, China; Key Laboratory of Physical Fitness Evaluation and Exercise Performance Monitoring of the General Administration of Sport of China, School of Physical Education, Southwest University, Chongqing 400715, China
  • About author:Liu Zhaozhi, Master candidate, School of Physical Education, Southwest University, Chongqing 400715, China; Key Laboratory of Physical Fitness Evaluation and Exercise Performance Monitoring of the General Administration of Sport of China, School of Physical Education, Southwest University, Chongqing 400715, China
  • Supported by:
    National Social Science Foundation of China, No. 21BTY092 (to PL); General Project of Chongqing Administration of Sport, No. B202206 (to HL)

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摘要：


文题释义：
运动：是指为了达到增强体质、预防疾病、促进健康等目标而进行的各种体育活动，包括有氧运动、高强度间歇训练以及民族传统健身运动等各种形式。通过定期的运动锻炼，可对人体身心健康产生良好影响，从而提升整体生活质量。随着研究深入，运动科学与其他领域相交叉，旨在更好地了解运动促进健康的内部机制。
肠道菌群：是指生存在人体肠道中的微生物群落。这些微生物在免疫调节、新陈代谢以及神经调节等生理过程中扮演着关键角色，与人体健康密切相关。肠道菌群被认为是未来疾病治疗的重要靶点，其菌群组成变化反映着宿主的健康水平。与此同时，它还参与宿主碳水化合物代谢、氨基酸代谢以及蛋白质消化吸收等多种功能，是人体的重要“器官”。

背景：运动对肠道菌群的调节与人体健康密切相关，但肠道菌群涉及多方面因素影响，国内外研究尚缺乏有关运动对大学生肠道菌群影响的较为一致的证据。
目的：探讨运动对大学生肠道菌群多样性和物种组成的影响。
方法：通过系统检索PubMed、Web of Science、Embase、Medline、Cochrane Library、中国知网、万方、维普数据库，筛选后纳入8篇实证研究，对其采用半定量的方法进行分析。
结果与结论：①在运动改变大学生肠道菌群物种多样性方面，高强度间歇训练和太极拳运动均能显著提升大学生肠道菌群的物种多样性，而有氧运动对大学生肠道菌群多样性的提升效果不显著；②在运动影响肠道菌群物种组成方面，3种运动方式均能显著改变大学生肠道中菌群的组成结构，可以提高瘤胃球菌、普氏粪杆菌、布劳提亚菌等有益菌的丰度，降低埃希氏菌属等有害菌的丰度；相较于高强度间歇训练，有氧运动和太极拳运动引起了更多有益菌丰度的提升；③除肠道菌群特征的变化外，运动还可以改善大学生体成分、心肺功能以及执行功能等，这些健康效益与运动引起的菌群变化密切相关，这些菌群可通过代谢调节、屏障功能以及神经调节对机体产生健康效益；④虽然目前已有研究证实了运动与肠道菌群存在关联，但运动影响肠道菌群的机制尚未明确，同时定位与宿主健康相关的菌群是未来以肠道菌群为治疗靶点的关键，这些均值得学者进一步关注和探究。
https://orcid.org/0009-0001-5304-4571( 刘昭志 )；https://orcid.org/0000-0001-8097-9260( 彭莉 )


中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

关键词: 运动干预, 大学生, 肠道菌群, 菌群多样性, 物种组成

Abstract: BACKGROUND: The regulation of intestinal flora by exercise is closely related to human health, but intestinal flora involves many factors. Existing studies have lacked consistent evidence on the effect of exercise on the intestinal flora of college students.
OBJECTIVE: To explore the effects of exercise on intestinal flora diversity and species composition of college students. 
METHODS: Through systematic search of PubMed, Web of Science, Embase, Medline, Cochrane Library, CNKI, WanFang Database and VIP database, eight empirical studies were selected and included, and semi-quantitative analysis was performed on them. 
RESULTS AND CONCLUSION: In terms of the species diversity of the intestinal flora, both high-intensity interval training and Tai Chi exercise significantly enhance the species diversity of intestinal flora in college students, while aerobic exercise does not have a significant effect on the enhancement of intestinal flora diversity in college students. In terms of the species composition of the intestinal flora, all three exercise modalities significantly alter the compositional structure of the intestinal flora in college students, which can increase the abundance of beneficial bacteria such as Ruminalococcus, Faecalis prevotelli, Blautia, and decrease the abundance of harmful bacteria such as Escherichia spp. Compared with high-intensity interval training, aerobic and Tai Chi exercise causes more elevated abundance of beneficial bacteria. In addition to changes in intestinal flora characteristics, exercise improves body composition, cardiorespiratory function, and executive function in college students, and these health benefits are closely linked to exercise-induced changes in intestinal flora that can produce health benefits for the body through metabolic regulation, barrier function, and neuromodulation. Although studies have confirmed the association between exercise and intestinal flora, the mechanism by which exercise affects intestinal flora has not yet been clarified, and at the same time, localizing the flora related to the host health is the key to targeting intestinal flora as a therapeutic target in the future, all of which are worthy of further attention and investigation.

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

Key words: exercise intervention, college students, intestinal flora, bacterial diversity, species composition

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