Preparation of tissue engineering scaffolds using rapid prototyping

doi:10.3969/j.issn.2095-4344.2013.08.018

Abstract

Abstract:

BACKGROUND: Rapid Prototyping is a high-tech manufacturing technique based on material accumulation to be combined with computer, numerical control, laser and material technologies.
OBJECTIVE: To review the application of rapid prototyping in the preparation of tissue engineering scaffolds.
METHODS: The first author retrieved Wanfang, CNKI, and Elsevier Science Direct Online for articles about biomechanical ability and developmental prospect of scaffold materials, as well as the application of rapid prototyping in the preparation of scaffold materials.
RESULTS AND CONCLUSION: Rapid prototyping has become mature gradually in the preparation of tissue engineering scaffolds. This technology can not only overcome the difficulty in shaping and internal microstructural control, but also optimize the scaffold structure via the finite element analysis, achieving some special requirements such as the improvement of mechanical strength. However, due to the particularity of tissue organ, and xenophobic sex and cell adhesion conditions, it is pre-requisite to combine rapid prototyping technology with biodegradable materials with histocompatibility in order to make the cells proliferation and differentiation better, promote tissue regeneration, and repair tissue defects.

Key words: biomaterials, biomaterial review, tissue engineering scaffolds, rapid prototyping, structure, repair, review, the National Natural Science Foundation of China

CLC Number:

R318

Zhang Jian-ming, Zhang Xi-zheng, Li Rui-xin, Ren Ting-ting, Li Hao, Wang He-yan, Hao Qing-xin, Wan Zong-ming, Li Jian-yu, Liu Lu. Preparation of tissue engineering scaffolds using rapid prototyping[J]. Chinese Journal of Tissue Engineering Research, 2013, 17(8): 1435-1440.

Figures/Tables 8

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