Stress relaxation properties of fetal umbilical cord vein grafts

doi:10.3969/j.issn.2095-4344.2013.16.015

Abstract

Abstract:

BACKGROUND: Human umbilical cord vein can serve as a good substitute for arterial grafts. Compliance of graft materials is a key problem during the transplantation expect for the matching between the umbilical cord vein and host’s artery.
OBJECTIVE: To detect the stress relaxation properties of fetal umbilical vein samples proximal and distal to the placenta.
METHODS: Fetal umbilical vein samples at the gestational age of 38-40 were taken from spontaneous delivery parturient women aged 22-28 years. Ten proximal placenta segments and 10 distal placenta segments were taken and placed on the electronic universal testing machine to do the stress relaxation test at (36.5±0.5) ℃. The strain was applied to the samples at a strain increases speed of 0.1%/s, and the setting time was 7 200 seconds. Totally 100 data were collected; and then, the normalized analysis method was employed to calculate the normalized stress relaxation equation.
RESULTS AND CONCLUSION: The stress at 7 200 seconds was decreased by 0.275 MPa in the proximal placenta segment group and 0.203 MPa in the distal placenta segment group. There was a significant difference between the two segment samples (P < 0.05). The stress relaxation curves of the two groups were changed with logarithmic relationship, and the proximal placenta segment and the distal placenta segment of fetal umbilical cord vein had different stress relaxation properties.

Key words: biomaterials, extracellular matrix materials, fetus, umbilical cord vein, proximal placenta segment, distal placenta segment, stress relaxation, contrast analysis

CLC Number:

:R318

Xu Dong-hui, Li Dong-yuan, Li Xin-ying, Ding Yue-hong. Stress relaxation properties of fetal umbilical cord vein grafts[J]. Chinese Journal of Tissue Engineering Research, 2013, 17(16): 2956-2960.

Figures/Tables 4

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