Hydrophilic acrylic intraocular lens: biocompatibility and complications following implantation

doi:10.3969/j.issn.2095-4344.2015.34.026

Abstract

Abstract:

BACKGROUND: Hydrophilic acrylic materials with good biocompatibility have been widely used in clinic. However, there are some problems about the biocompatibility and safety of hydrophilic acrylic intraocular lens after long-term clinical application.

OBJECTIVE: To discuss the biocompatibility and stability issues and corresponding processing methods after hydrophilic acrylic intraocular lens implantation.

METHODS: A computer-based search of Wanfang and PubMed database was performed for articles related to clinical application of hydrophilic acrylic intraocular lens published from 2005 to 2014. The keywords were “hydrophilic acrylic，intraocular lens” in Chinese and English, respectively. A total of 618 articles were initially retrieved, and finally 35 articles were included in result analysis.

RESULTS AND CONCLUSION: As the hydrophilic acrylic intraocular lens is foldable, a small incision is required for implantation and the operation is simple that cause less damage to the patients. In addition, the hydrophilic acrylic intraocular lens has poor bacterial and inflammatory cell adhesion, which leads to a low probability of infective endophthalmitis after implantation. But there is a high incidence of posterior capsule opacification as well as some refractive errors and visual quality problems after implantation. Taken together, to solve these problems depends on the continuous improvements and updates of intraocular lens materials and designs.

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

Key words: Phakic Intraocular Lenses, Methylmethacrylates, Histocompatibility, Biocompatible Materials

CLC Number:

:R318

Wei Fen, Ai Ming. Hydrophilic acrylic intraocular lens: biocompatibility and complications following implantation[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(34): 5547-5551.

Figures/Tables 2

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