Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (34): 5552-5558.doi: 10.3969/j.issn.2095-4344.2015.34.027

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Self-fixating mesh and sutured mesh in open inguinal hernia repair: a Meta-analysis

Wang Jia-sheng, Yang Lei, Kang Xiao-lan, Chen Yong   

  1. People’s Hospital of Dazu District, Chongqing 402360, China
  • Online:2015-08-20 Published:2015-08-20
  • Contact: Chen Yong, Associate chief physician, People’s Hospital of Dazu District, Chongqing 402360, China
  • About author:Wang Jia-sheng, Master, People’s Hospital of Dazu District, Chongqing 402360, China

Abstract:

BACKGROUND: It remains controversial in term of therapeutic efficacy of self-fixating mesh and sutured mesh in inguinal hernia repair.

OBJECTIVE: To compare the therapeutic effects of self-fixating mesh and sutured mesh in open inguinal hernia repair with Meta-analysis.

METHODS: Comprehensive electronic search strategies were developed using the following electronic databases: Cochrane library, PubMed, EMBASE, Medline, Ovid, CNKI, Wanfang and FMJS. The Literature published before December 2014 was searched. Perspective randomized controlled trials about comparing self-fixating mesh and sutured mesh in open inguinal hernia repair were included. A data-extraction sheet was developed based on the preset standards. The data from eligible studies were pooled through Meta-analysis.

RESULTS AND CONCLUSION: Nine trials with a total of 2 100 inguinal hernia patients met the inclusion criteria, including 1 033 cases of self-fixing mesh and 1 067 cases of sutured mesh. The Meta-analysis showed that no significant differences were found between the two groups in the recurrence rate, seroma, hematoma, wound infection, pain, foreign body sensations (P > 0.05), but the duration of operation was less in the self-fixing mesh group than the sutured mesh group (P < 0.05). According to limited evidence, there are some findings as follows: self-fixating mesh is equivalent to sutured mesh in the therapeutic effects on open inguinal hernia repair. Because of the limits of samples and literature quality, more large-sample and high-quality trials are required to make a definite clinical evidence to use self-fixating mesh for groin hernia repair.

中国组织工程研究杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松组织工程

Key words: Hernia, Inguinal, Meta-Analysis, Evidence-Based Medicine

CLC Number: