Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (12): 1904-1908.doi: 10.3969/j.issn.2095-4344.2015.12.019

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Silicone materials for breast augmentation influence the state of human oral mucosa cells

Ding Yan-mei   

  1. Department of Stomatology, Tianshui Hospital of Integrative Medicine, Tianshui 741020, Gansu Province, China
  • Revised:2015-02-05 Online:2015-03-19 Published:2015-03-19
  • About author:Ding Yan-mei, Attending physician, Department of Stomatology, Tianshui Hospital of Integrative Medicine, Tianshui 741020, Gansu Province, China

Abstract:

BACKGROUND: Previous studies have shown that the survival state of oral mucosal cells directly is directly affected by the nutritional status of the body, therefore, it may be a good indicator of the surgical nutritional status. But whether this index also influences surgical trauma stimulus is still unclear.
OBJECTIVE: To observe the effect of breast augmentation with silicone implants on the survival status of oral mucosal cells.
METHODS: Thirty-two female patients scheduled for breast augmentation with silicone implants, including 13 cases of reproductive history and 19 cases of non-reproductive history, aged 23-45 years old. Sub-G1 peak method and Ki-67 were used to detect the proliferation and apoptosis rates of oral mucosa cells before and after breast augmentation with silicone implants for statistical comparisons.
RESULTS AND CONCLUSION: All the 32 cases successfully completed breast augmentation with silicone implants, and no serious adverse events occurred perioperatively. The oral mucosa cell apoptosis and proliferation rates were (27.3±6.2)% and (27.8±5.8)% before breast augmentation, and (27.8±5.8)% and (20.2±7.7)% after breast augmentation. There was no difference before and after breast augmentation (P > 0.05). These findings indicate that the proliferation and apoptosis of human oral mucosa cells cannot be significantly by breast augmentation-related trauma, and the survival state of oral mucosa cells has some value to assess the nutritional state of breast augmentation recipients.


中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程


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Key words: Silica Gel, Cell Proliferation, Apoptosis

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