Abstract:

BACKGROUND: Synthetic patch as an important substitute to pelvic tissue can replace damaged pelvic fascia tissue, and has been widely used in the pelvic floor reconstruction.
OBJECTIVE: To observe the efficacy and complications of pelvic floor reconstruction with mesh, and to explore its safety and effectiveness.
METHODS: Forty-five pelvic organ prolapse female patients were divided into two groups according to patient’s willingness: experimental group, pelvic floor reconstruction with mesh (n=25); control group, transvaginal hysterectomy combined with vaginal wall repair (n=20). Perioperative conditions were recorded, and uterine prolapse staging, complications, pelvic floor function, pelvic discomfort, as well as an objective cure rate were evaluated in the two groups during the follow-up.
RESULTS AND CONCLUSION: Compared with the control group, the experimental group was characterized as shorter operative time, less amount of bleeding, milder infections, and faster recovery (All P < 0.05). At 6 months of follow-up, the score on uterine prolapse staging was higher in the experimental group than the control group; at 12 months, the scores on pelvic floor function and pelvic discomfort as well as the incidence of complications were significantly lower in the experimental group (P < 0.05), but the objective cure rate was higher compared with the control group (P < 0.05). These findings suggest that pelvic floor reconstruction with mesh for pelvic organ prolapsed can reduce the operative time and blood loss and promote postoperative recovery. Meanwhile, it can significantly improve pelvic floor function, pelvic discomfort, postoperative complications, the rate of exposure, and the objective cure rate, which is safe and effective during the short-term follow-up.

Key words: Polypropylenes, Pelvic Organ Prolapse, Pelvic Floor