Embolization of dog’s bilateral internal iliac arteries with gelfoam powder

doi:10.3969/j.issn.2095-4344.2013.08.015

Abstract

Abstract:

BACKGROUND: Gelfoam has become the preferred embolization agent for preoperative embolism in the operation of sacral tumor, but the contribution of small gelfoam to embolization effectiveness and postoperative complications has not been definitely reported.
OBJECTIVE: To observe the changes in intraoperative bleeding and complications following embolization of dog’s bilateral internal iliac arteries with gelfoam powder.
METHODS: The bilateral internal iliac and median sacral arteries of fifteen dogs were embolized using gelfoam powder with a diameter of 50-150 μm. Then, the operation of sacral tumor was imitated to measure intraoperative bleeding at 1, 2, and 3 days after embolization, observing pathological alteration of pelvic organs.
RESULTS AND CONCLUSION: The mean intraoperative bleeding was higher at 3 days than at 1 and 2 days (P < 0.0.5), but it was no difference at 1 and 2 days (P > 0.05). When gelfoam power with a diameter of 50-150 μm was employed to embolize the bilateral internal iliac and median sacral arteries, the smallest embolized artery was arteriole whose diameter was about 50 μm, but embolized arteries were mainly arterioles with a diameter of 100-200 μm. The first-class branches of embolized bilateral internal iliac and median sacral arteries were reserved which were displayed on the digital subtraction angiography. In addition, pelvic organs had no obvious pathological alteration.

Key words: biomaterials, material biocompatibility, basic experiments of biomaterials, gelfoam powder, internal iliac artery, embolism, angiography, sacral tumor, provincial grants-supported paper, biomaterial photographs- containing paper

CLC Number:

R318

Wang Wei, Yin Zong-sheng, Li Ye-tian, Qin Kun-peng. Embolization of dog’s bilateral internal iliac arteries with gelfoam powder[J]. Chinese Journal of Tissue Engineering Research, 2013, 17(8): 1418-1422.

Figures/Tables 2

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